Description overdue on 02/07/2014
- Latin name: Amosin
- ATC code: J01CA04
- Active substance: Amoxicillin (Amoxicillin)
- Manufacturer: Synthesis of (Russian)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Amosin. Indications for use drugs
- Contraindications
- Side effects
- Amosin, instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Reviews
- Price, where to buy
Composition
The preparation includes Amoxicillin as the active substance and excipients such as a dextrose . sodium glutamate monohydrate , Sodium phosphate dibasic, polyvinylpyrrolidone (povidone), disodium EDTA (Trilon B), and vanillin Sucrose and food flavoring.
Product form
Antibiotic Amosin produced in the form powder . granules . suspension As well as in the form of solution for intramuscular and intravenous administration .
Pharmacological action
Antibiotic Amosin is antimicrobial, which has a strong bactericidal effect.
Pharmacodynamics and pharmacokinetics
After receiving the tablet is almost completely absorbed in the digestive tract quickly. On the absorption of the drug meal has no effect. At high concentrations of active drug can be detected in plasma, bronchial secretions, sputum, urine, lung tissues of female sex organs, the gallbladder and intestinal mucosa.
Often when metabolism amoxicillin forms inactive metabolites . In 50-70% of amoxicillin appears unchanged in the urine - by tubular excretion (80%) and glomerular filtration rate (20%). Also, using the bile - 20%.
Amosin. Indications for use drugs
What are the indications for use Amosina? First of all, this medicine is used for bacterial infections, which are caused by susceptible pathogens. It can be an infection of the respiratory tract, the genitourinary system, upper respiratory tract, skin and soft tissue, abdominal infections and infections of the digestive tract.
Amosin used in leptospirosis . meningitis . Listeriosis . sepsis . gonorrhea . Lyme disease . Indications Amosina quite extensive. It can also be used for prevention endocarditis and surgical infection.
Contraindications
As contraindications may be complications such as Lymphocytic Leukemia , Infections of the gastrointestinal tract, accompanied by vomiting and diarrhea . allergic diathesis , Respiratory viral infections, hay fever .
If the drug is used in combination with metronidazole , There may be diseases of the nervous system, increased sensitivity to derivatives nitroimidazole .
Side effects
Many are interested in not only from what Amosin pills, but what he may have side effects.
Allergic reactions - Erythema, angioedema, urticaria, rhinitis, pain in the joints, in rare cases - anaphylactic shock . Patients who suffer from chronic diseases or low resistance of the organism may develop superinfections .
If taking the drug for a long time and at high doses, it can lead to dizziness . confusion . ataxia . depression . convulsions .
In combination with metronidazole possible vomiting . nausea . constipation . diarrhea . anorexia . stomatitis . glostit .
When combined with clavulanic acid you may receive cholestatic jaundice . hepatitis In rare cases - toxic epidermal necrolysis . erythema multiforme . exfoliative dermatitis .
Amosin, instructions for use (method and dosage)
This antibacterial drug is intended for oral administration. Tablets Amosin taken regardless of mealtime. They can grind and divide. The duration of treatment and the dose determined by the physician, it is recommended to take the drug at regular intervals.
Children's version of the application - usually for children aged 10 years and adults, body weight over 40 kg, it is recommended to take the drug three times a day 500 mg. In case of severe treatment dose can be increased up to 1000 mg. Children aged 5 to 10 years should receive Amosin 250 mg thrice a day. The average duration of treatment is 5-12 days. Usually, treatment is continued for another 2-3 days after the disappearance of symptoms.
Instructions for use Amosina in special cases:
- If you have an acute form of uncomplicated gonorrhea , The drug must be taken one per day in a dose of 3000 mg.
- In the presence of gastrointestinal disease or gynecological diseases of bacterial etiology Amosin must be taken three times a day at 1500-2000 mg or four times daily 1000-1500 mg.
- Patients who suffer from renal failure, need to change the multiplicity of the drug, while maintaining its dosage. The recommended dose is usually taken at intervals of 12 hours.
- For children who take the drug for prevention, it is recommended to start with half the adult dose.
- During pregnancy It should be especially careful with this medication. It is necessary to consult with your doctor and weigh the potential benefits to themselves and the potential risk to the fetus.
- For children specific instructions for use is not - the drug should be taken according to the dosing regimen. If there is an option to combine with metronidazole , The patients who are younger than 18 years, taking this medicine is not necessary.
- With sore throat also often recommend taking Amosin. Since the most common cause of angina are different kinds of bacterial infections.
Overdose
You must correctly understand from what Amosin help, and in some cases it is harmful. Of course, drug overdose unpleasant and dangerous to health. In the case of receiving higher doses of the drug may develop in patients vomiting . nausea . diarrhea , Epigastric pain, possible disruption of water and electrolyte balance.
In case of overdose, the patient should wash the stomach and assign enterosorbentnye funds . In the case of symptoms of overdose Symptomatic treatment is necessary. It is also advisable to be the appointment of laxatives and performing procedures that maintain water and electrolyte balance.
Cooperation
In combination with Glucosamine . antacids , Laxatives, aminoglycosides and food may decrease the absorption of the drug.
With the simultaneous acceptance Amoxicillin and ascorbic acid Conversely enhanced absorption of the drug. The same occurs in the case of a combination with antibacterial antibiotics.
Women who combine with Amosin combined contraceptive , Should take additional Contraceptives , for example, barrier .
If concomitant use of NSAIDs increased plasma concentrations of Amoxicillin .
In the case of simultaneous application of medications with allopurinol possible development of allergic skin reactions.
Terms of sale
The drug Amosin available on medical prescription.
Storage conditions
The drug should be stored in a place protected from light and moisture, at temperature not more than 25 ° C.
Shelf life
Shelf life is 2 years.
Analogs of the drug
Amoxil
Ekobol
Ospamoks
Ampioks
Amoxicillin
Ampicillin
Flemoksin soljutab
Analogs - is the same pharmacological preparations groups that possess the same or exactly the same effect. Amosina they have the following:
- Amoxicillin
- Flemoksin Soljutab
- Ekobol
- Amoksisara
- Hikontsil
- Danemoks
- Gryunamoks
- Gonoform
- Ospamoks
Reviews Amosine
If you have not yet decided whether or not you buy the drug, reviews Amosine help you evaluate it and make a decision. Reviews generally positive, many write that for quite a reasonable price this drug has a rapid action - in the shortest possible time it is able to remove the corresponding symptoms and accelerate the treatment of the disease. An important factor is also the fact that during the treatment the patients did not cause any discomfort.
Price Amosina where to buy
Price in Russia is about 50 rubles. Price Amosina 500 mg equals approximately 70 rubles.