Description overdue on 06/06/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

1 tablet: Amoxicillin   500 mg of amoxicillin in the form of trihydrate and Clavulanic acid   125 mg of potassium clavulanate .

As additional substances: microcrystalline cellulose, calcium stearate, sodium krohmalglikolat, silica.

The composition of the shell: hydroxymethyl cellulose, lactose, titanium dioxide, macrogol.

Product form

The coated tablets in a blister of 7 pieces.

Pharmacological action

Amoxicillin   is a semisynthetic antibiotic, it has a wide range of activity against microorganisms. Sensitive to beta-lactamase, therefore collapses under its influence and activity against bacteria, producing the substance.

Clavulanic Acid   inactivate beta-lactamase. Her presence in the formulation retains Amoxicillin   from degradation by the enzyme, and thereby, the spectrum of action Amoxil K 625 expands and allows use against resistant microorganisms amoxicillin .

Amoxil 625 K exhibits bactericidal activity against most species of bacteria (both aerobic and anaerobic). These include widespread pathogens Diphtheria . aurococcus , Enterococci, Staphylococcus epidermidis, streptococci pneumonia, Clostridium, Escherichia coli . gardnerella . Helicobacter , Neisser gonorrhea . Salmonella and Shigella , Vibrio cholerae, Chlamydia and treponemy .

Pharmacodynamics and pharmacokinetics

All components of the preparation is completely soluble in aqueous solutions and are well absorbed in the stomach. When taken before meals improves absorption.

The maximum level of the drug in the blood occurs within 60 minutes of exposure. Receiving simultaneously Probenecid may slow excretion Amoxicillin   excreted.

The drug is widely distributed in tissues and interstitial fluid. It does not accumulate.

Both components may be identified in breast milk and pass through the placenta. However, the harmful effects on the fetus have been identified.

The bulk of the renal elimination half-life of about 6 hours.

Indications

What kind of pills - Amoxil 625 K? Tablets useful in the treatment of infections caused by susceptible organisms:

• Otolaryngology - otitis . sinusitis . tonsillitis ;
• respiratory system - pneumonia, pneumonia . bronchitis ;
• soft tissue infections - wounds abscesses Burns;
• dentoalveolar abscesses;
• osteomyelitis ;
• infections of the urinary - pyelonephritis . cystitis . urethritis ;
• sepsis   of different origin.

Contraindications

Individual intolerance to beta-lactam antibiotics (penicillins and cephalosporins). Having a history liver dysfunction   or jaundice That are associated with Amoksilom TO 625.

Side effects

Infectious lesions: candidiasis   skin and mucous membranes.

The immune system: angioedema , Serum sickness, allergic vasculitis . anaphylactic shock .

Blood system: thrombocytopenia .   leukopenia Increase the duration of bleeding, agranulocytosis . anemia .

CNS: seizures (renal impairment), dizziness, headache.

Digestive system: nausea . vomiting . diarrhea . colitis .

The system of the liver and zhelchevyvedeniya: increase in liver enzymes, cholestatic jaundice . hepatitis . These effects are reversible.

Skin: hives . itch . erythema   polymorphic nature, Stevens . exfoliative dermatitis . toxic epidermal necrolysis .

Urinary system: crystalluria Interstitial nephritis .

Instructions for use (method and dosage)

In the treatment of infections of the middle and mild children after 12 years and adults use one tablet twice a day. Tablets are chewed and not swallowed whole. If necessary, it can be divided in half.

Tablets are recommended to take at the beginning of a meal to reduce the side effects from the digestive organs.

The course of treatment is not more than 14 days.

With impaired renal function, a dose given clearance creatinine .

Overdose

The signs are the symptoms of disorders of the digestive system, as well as changes in water and electrolyte balance. Use symptomatically.

Cooperation

Probenecid reduces the excretion Amoxicillin   kidney and leads to an increase in its blood level, however undesirable simultaneous reception.

Application to allopurinol   increases the possibility of allergic reactions in the skin.

Amoxil 625 By the effect of oral contraceptives   decreases.

In the case of treatment anitikoagulyantami , Requires constant monitoring of blood coagulation.

Terms of sale

Prescription.

Storage conditions

Temperature not exceeding 25 ° C.

Shelf life

2 years.

Cautions

For instructions on Amoxil 625 warns of the need for pre-treatment to ensure that there are no allergy to penicillin or cephalosporins.

If you suspect kissing disease   the drug is not prescribed.

If abnormal liver function used with caution.

To reduce the likelihood of crystalluria   should in the course of treatment to maintain a balance between the urine derived and drink fluids.

Analogs

Augmentin . Amoxiclav . Flemoklav Soljutab .

Babies

Not indicated for children under 12 years.

During pregnancy and lactation

Recommended avoided during pregnancy . If necessary, the drug should be weighed against the benefits to the mother and the risk to the fetus.

During lactation To use Amoxil 625 possible. The harmful effects for the child, with the exception of hypersensitivity, have been identified.

Reviews

Most reviews of the preparation are to treat respiratory and ENT. The drug is widely used, patients say they are very good at helping bronchitis. In the treatment of rapidly decreases cough Decreases temperature , Improves the general condition. Many reviews say that the recovery is faster.

Price Amoxil By 625 where to buy

The cost in Ukraine ranges from 42 to 59 UAH. per pack of 14 tablets.

In Moscow, the price of Amoxil 625 K on average 290 rubles.