Description overdue on 05/06/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Amoxil (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

1 tablet contains Amoxicillin   250 or 500 mg of amoxicillin trihydrate .

Additional ingredients are: calcium stearate, sodium krohmalglikolat, povidone.

Product form

Tablets are white with a yellow tinge to 10 pcs. in blister.

Pharmacological action

Antibiotic It refers to the group aminopenicillins , Has a broad spectrum of action. Inhibiting cell wall synthesis, provides   bactericidal   effect. Active respect staphylococci . streptococci , Corynebacteria Diphtheria , Enterococci, E.   and Haemophilus sticks , Neisseria gonorrhea   and meningitis . Proteus . Salmonella   and Shigella; and anaerobes - clostridia , Peptostreptokokki and peptokokki.

Together with the application metronidazole   It shows efficacy against Helicobacter pylori . Microorganisms capable of producing penitsillinazou It is resistant to the drug.

Amoxil relatively inactive mycoplasmas . mycobacteria . mushrooms . Rickettsia . Plasmodium . amoebas . Virus And Pseudomonas aeruginosa and Proteus.

Pharmacodynamics and pharmacokinetics

The drug is well absorbed after oral administration. Maximum concentration in the blood occurs within 2 hours. The half-life of 90 minutes. The bulk of the excreted by the kidneys unchanged.

Indications

Amoxil tablets, from what are they? They are used to treat infections of organs and systems, which are caused by microorganisms sensitive to the drug:

• gastrointestinal tract;
• the respiratory system;
• skin and soft tissues;
• sexual and urinary systems.

For the treatment of gastrointestinal diseases caused by Helicobacter , A combination with metronidazole   or clarithromycin .

Contraindications

• idiosyncrasy of the drug as well as other antibiotics penicillin. With increased sensitivity to cephalosporin   antibiotics should be aware of the likelihood of cross-allergy nature;
• Lymphocytic Leukemia   and kissing disease ;
• children under 1 year;
• lactation.

Side effects

An allergic reaction in the form itching . hives . fever . hyperemia . Stevens . hyperkeratosis . epidermal necrolysis . eczema , Bullous dermatitis . angioedema . vasculitis . serum sickness . anaphylactic shock .

Digestive tract : Loss of appetite, nausea, dry mouth, vomiting, diarrhea, flatulence , Colitis, change indicators of liver enzymes upward, hepatitis, jaundice.

Nervous system : Insomnia, anxiety, loss of consciousness, dizziness . hyperkinesis , headache. With the defeat of renal function may be convulsions.

Forming Organs :   thrombocytopenia . leukopenia . hemolytic anemia Increase in prothrombin index.

The urinary system : Interstitial jade .

Among other reactions can occur superinfection candidiasis   mucous membranes, weakness, false-positive reactions to certain Glucose   and urobilinogen in the urine.

Instructions for use Amoxil (method and dosage)

Apply pills prescribed by a doctor, regardless of the meal.

Dosage in diseases of middle and low severity:

• adults and children after 10 years - 500-750 mg 2 times a day;
• children 3 to 10 years, 750 mg per day in 3 divided doses;
• from 1 to 3 250 mg twice a day.

In the case of chronic recurrent disease and in severe adults take 3 grams per day; Children - 60 mg / kg body weight, divided into 3 doses.

The daily dose for adults is a maximum of 6

The treatment was continued for 3 days after cessation of symptoms. Infections of mild to moderate severity include treatment of about 1 week. In the case of infection with streptococcus beta -hemolytic treatment is not less than 10 days.

For the treatment of acute uncomplicated gonorrhea   administered once 3, in combination with Probenecid   in an amount of 1 g

At a stomach ulcer for eradication Helicobacter pylori   Instructions on Amoxil 500 mg results in the scheme, which should be used in combination with other drugs:

• Amoxil 2 grams per day in two divided doses in combination with clarithromycin   500 mg twice daily and omeprazole   at a dose of 40 mg per day.
• Amoxil 2 grams per day, metronidazole   400 mg three times a day omeprazole   40 mg per day.

The treatment course is 1 week.

In renal failure designate considering glomerular filtration rate and level in clearance creatinine .

Overdose

In case of excess doses of symptoms of nausea and vomiting, diarrhea, disturbance of water and electrolyte balance.

For the treatment of stomach washed, use saline laxatives, activated carbon , Symptomatic treatment.

Cooperation

Amoxil pills when taken with oral contraceptives may decrease the effect of contraceptives and increase the chance of bleeding.

Increased absorption Digoxin   and increased toxicity Methotrexate .

In an application with Probenecid, phenylbutazone, sulfinperazonom, Indomethacin   and acetylsalicylic acid   Amoxil excretion by the kidneys is slowed down.

Drugs that have a bacteriostatic effect ( chloramphenicol . macrolides . tetracycline ), Neutralized the effect Amoxil.

The combined use of allopurinol   increase the likelihood of allergic skin reactions.

The simultaneous appointment antacids   reduces the absorption of Amoxil.

Combination with anticoagulants   It increases the likelihood of bleeding, so you need to control the rate of prothrombin time.

Diarrhea   reduces the absorption of the drug.

In pregnant women the drug reduces the concentration Estradiol   in urine.

Terms of sale

Prescription.

Storage conditions

The temperature is not above 25 ° C.

Shelf life

4 years.

Cautions

Should exclude the possibility of developing an allergy to the cephalosporin antibiotics and penicillin prior to treatment.

Repeated and prolonged use leads to the development of resistance and superinfection.

Vomiting and diarrhea reduces the absorption of the drug, in these conditions it should not be given.

Use with caution in patients with asthma   and allergic diathesis .

The drug in high doses causes the development of crystalluria Therefore necessary for preventing reception of a sufficient amount of liquid.

The drug can change the color of tooth enamel in children, so you need to monitor compliance with the hygiene of teeth and mouth.

If anaphylactic shock is carried out artificial respiration is administered epinephrine , Used antihistamines . glucocorticoids   and oxygen .

Analogs Amoxil

Ospamoks . Flemoksin Soljutab . Ampioks . Amoxicillin

Babies

Is contraindicated in children under 1 year.

During pregnancy and lactation

If necessary, use should weigh the benefits to the mother and the risk to the fetus.

Amoxil teratogenic effects was not identified.

A small amount of the drug is in breast milk. Appointment during lactation is possible, but is recommended for the prevention of sensitization on the treatment to stop breast-feeding.

Reviews Amoksile

Studying reviews Amoksile, we can see that it is quite affordable and effective medication. A lot of good reviews on the application at bronchitis . pneumonia   and tonsillitis As in adults, and children. Patients who used the drug, say a quick recovery.

There are also some positive responses use in streptoderma   pustular and other skin lesions.

A disadvantage is the appearance in some patients the side effects such as skin rash or gastrointestinal disorders.

The advantage is also a fact that due to security Amoxil pills are allowed to use at pregnant   and nursing.

Price Amoxil where to buy

Ukraine Amoxil is sold at an average price of 19 USD. 20 tablets of 250 mg. Price Amoxil 500mg is from 29 to 34 UAH.