Description overdue on 05/29/2014
- Latin name: Azitrox
- ATC code: J01FA10
- Active substance: Azithromycin (Azithromycin)
- Manufacturer: JSC "Pharmstandard-Leksredstva" Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications for use of the drug Azitroks
- Contraindications
- Side effects
- Instructions for use Azitroks (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- Reviews
- Price, where to buy
Composition
In the preparation of capsules contained azithromycin dihydrate in an amount of 250 mg or 500 mg, depending on the form of production, special auxiliaries. The suspension contains 0, 2 g of the base material.
Product form
Available in Azitroks capsules 250 and 500 mg and as suspension Which is taken orally. One pack capsules may comprise from 2 to 10 capsules, suspensions proposed in vials of 5-20 ml.
Pharmacological action
Antibiotic broad spectrum of activity.
Pharmacodynamics and pharmacokinetics
Azitroks - an antibiotic with a broad spectrum of activities related to azalides . The drug has an effect on various types of bacteria, inhibiting their synthesis and slowing growth. The bactericidal action of the drug is as against intra- and extracellular pathogens. Antibiotic activity aimed at Gram negative bacteria . gram-positive cocci Some streptococci and anaerobic microorganisms, and so forth.
But azithromycin no effect on gram-positive bacteria which are resistant to erythromycin .
After receiving antibiotics are absorbed from the gastrointestinal tract, and after 2, 5-3 hours in the composition of the plasma concentration reached a maximum. Simultaneous reception with food can slow down and reduce the absorption of the active substance.
In the body, azithromycin able to maintain 5-7 days after application of the last dose, so the permissible use of short courses of 3-5 days of therapy. When injected into the liver azithromycin able demethylated to form inactive metabolites . Active substance from plasma displays in two stages, making the periods of 14-20 hours and 41 hours.
Indications for use of the drug Azitroks
The drug is prescribed in the treatment of Infectious Diseases That cause certain microorganisms exhibiting sensitivity to Azithromycin .
Therefore, the indications for use of the drug may include various infectious lesions:
- covers skin or soft tissue;
- urogenital system;
- respiratory and otolaryngology, and so on.
Contraindications Azitroks
Contraindications include:
- high sensitivity to the presence of the drug or other means macrolide ;
- age of patients less than 12 years;
- various pathological liver and kidney.
With caution it is administered to pregnant and lactating patients, and patients suffering from arrhythmia .
Side effects
The drug can cause a variety of disorders in patients, affecting the cardiovascular and nervous system. In addition, there may be deviations in the work of the digestive tract, the development of allergic reactions and fungal infections , eg, vaginal candidiasis .
Instructions for use Azitroks (method and dosage)
This drug is recommended to be taken once a day for an hour before eating a meal or 2 hours after. A single dose is one capsule which should be taken whole, plenty of drinking water.
Instructions on Azitroks 500 mg reports that this form of the drug is prescribed for adult patients, and take the capsules for three days. Thus 250 mg of the drug is often used in the treatment of less complex forms of the disease. However, the doctor may install individual dosage and duration of treatment for a particular patient, depending on the complexity and features of the disease.
Overdose
In case of overdose may express symptoms related to side effects. It is also possible occurrence of undesirable symptoms such as violations of the chair . nausea and vomiting . Further increase of the dose is often reversible loss of hearing .
In such cases, prescribe gastric lavage Applying enterosorbents , Symptomatic therapy.
Cooperation
When treating Azitroks should observe a break of at least 2 hours between taking this antibiotic, and antacids . In addition, the observed amplification efficiency ergot alkaloids and dihydroergotamine , Synergism chloramphenicol, tetracycline , Reduce the impact of lincosamides .
Antacids, ethanol and food can slow down and reduce absorption. But if some substances and influence the effectiveness of the drug, then Heparin This antibiotic is pharmaceutically incompatible.
Terms of sale
The drug is available over the counter prescription specialist.
Storage conditions
This antibiotic should be stored in a relatively dry place, protected against the sun's rays, keeping the temperature of + 15-25 degrees C.
Shelf life
The drug is stored for 2 years, if the conditions of storage.
Analogs Azitroks
Klatsid
Klatsid CP
Rulid
Klabaks
Fromilid
Hemomitsin
Vilprafen
Rovamycinum
Roxithromycin
Clarithromycin
Azithromycin
Midecamycin
Sumamed
Drugs with similar action are: Azivok . Zitrotsin . Azitral . Sumamed and others. These analogs Azitroks also established on the basis of the active substance - azithromycin .
Alcohol and Azitroks
When the treatment of patients Azitroks use alcohol It could negatively affect the functions of the liver. The fact that in addition to the processing of the antibiotic and elimination of the decay products, and splitting must be ethanol. Alcohol also inhibits the production of enzymes that help remove harmful elements decay, and blood gets is not a cure, and harmful substances.
Reviews on Azitroks
As numerous reviews Azitroks, the drug is highly effective and thanks to its strong effect helps to treat complicated infections.
Another problem is the use of antibiotics without prescription specialist. Therefore, doctors often reviews contain information about the consequences of such a careless treatment. In any case, prior to treatment of the disease should consult a doctor first and determine the infectious agent in terms of its sensitivity to this drug.
Price Azitroks where to buy
Buy this drug from pharmacies can cost 170-290 rubles. The price Azitroks 500 mg, packaging of which includes 3 capsules in Moscow is in the range 246-290 rubles, and in Ukraine - 118-130 UAH.