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 Oletetrin
 Combination antibiotic . The active components are the tetracycline and oleandomycin. The drug has a broad spectrum antibacterial effect . With regard to microbial bacteriostatic. Teteratsiklin effective against gram-negative and gram-positive microorganisms. Oleandomycin affects gram-positive cocci , and staphylococci , Resistant to tetaratsiklina and other antimicrobials. Resistance of microorganisms to a combination of drugs is developing much more slowly than each of the components separately. Oletetrin available in tablet dosage form, in the form of capsules.

Indications:

Oletretrin prescribed for tonsillitis, pharyngitis, pneumonia, otitis media, cystitis, pyelonephritis , Cholecystitis, bronchitis, sinusitis, pneumonia, osteomyelitis, brucellosis, tularemia, gonorrhea, urinary tract infections, purulent meningitis , Erysipelas, prostatitis, endometritis , Purulent infection of the soft tissue and skin.

Contraindications:

Instructions for use of the drug is not recommended for oletetrin medication intolerance to tetracycline antibiotics, oleandomitsina at child bearing, mycosis in children's medical practice until the age of 8, when breastfeeding, severe liver disease and kidney systems.


Side effect:

Against the background of treatment may develop oletetrin epigastric pain , Diarrhea syndrome, allergic reactions in the form of eosinophilia , Skin rash and itching. Among the side effects from long-term treatment of the most frequent dyspepsia, anemia, intestinal dysbiosis, candidiasis, hypercreatininemia , Elevated liver enzyme system, azotemia, hypercreatininemia, photosensitization , Hyperbilirubinemia, hemolytic anemia, develop beriberi (vitamin K and B group).

Mode of application:

Oletetrin taken orally. The maximum daily dosage is 2 grams. Adults   prescribers 4 times a day for 0, 25 grams. For children from 8 years   daily dosage is calculated according to the scheme of 20-30 mg per 1 kg of body weight of the child, combined antibiotic take 4 times a day. Perhaps intravenous bolus dose of the antibacterial agent in 0, 2-0, 3 grams (diluted in distilled or double distilled water). Injection Speed ​​- 2 ml per minute. Oletetrin can be administered intravenously, after dissolving the drug in a solution of dextrose or sodium chloride. Drip injection rate - 60 drops per minute. The duration of antibiotic therapy is 5-10 days oletetrin (correction dosing regimen and duration of therapy is carried out depending on the severity of the infection, tolerability and efficacy oletetrin).

Special instructions:

Treatment antibacterial drug oletetrin during tooth development may cause permanent changes in their tone and color. The drug can affect the ability to drive a motor vehicle. Price oletetrin preparation varies depending on the pharmacy network (on average 100-200 rubles).

Drug Interactions:

The adsorption of the drug is reduced when taking oletetrin antacid medications , Formulations which contain iron in its composition, with the use of foods and drugs containing magnesium ions, aluminum and calcium.