Description overdue on 09/23/2013

Antibiotics penicillin. The principle is based on the impact of the suppression of the process of synthesizing the cell wall. Phenoxymethylpenicillin is bactericidal effect against most Gram-positive bacteria   (streptococcus, staphylococcus), a small portion Gram-negative cocci   (neisserial) treponem korinobakteriey, Listeria. Herbal medicine has no effect on Streptococcus spp., The main difference of which is the ability to independently produce penicillinase (specific enzyme cleaves and inactivates beta-lactam antibiotics). Phenoxymethylpenicillin no impact on the life of viruses, pathogens amoebiasis Most Gram-negative cocci, Rickettsia. The active component is considered acid-resistant, it collapses in contact with penicillinase. The medicament is discharged in the form of a syrup, granules, drops, pills, in tablet dosage form. Buy Phenoxymethylpenicillin at any pharmacy network, presenting a doctor's prescription form.

Indications:

Antibacterial drug Phenoxymethylpenicillin prescribed for infectious lesions of the oral cavity ( actinomycosis , Periodontitis, bacterial stomatitis), respiratory system (pneumonia, bronchitis), skin and adjacent soft tissues ( contagious impetigo , Cellulitis, abscess, abrasions, skin rash erythematous migratory nature erysipeloid). Instructions for use of the drug is recommended to appoint Phenoxymethylpenicillin medication at botulism , Tetanus, lymphadenitis (inflammatory disease of the lymphatic system), with diphtheria anthrax , Syphilis, gonorrhea, leptospirosis. The drug is indicated for the prevention of recurrence bacterial endocarditis , Rheumatoid arthritis, minor chorea, glomerulonephritis, rheumatism And for prevention of infection after surgery.

Contraindications:

Tablets Phenoxymethylpenicillin not prescribed for severe infectious diseases, intolerance of cephalosporins, penicillin, carbapenem and other beta-lactam antibiotics, with aphthous pharyngitis   and stomatitis, diseases of the digestive tract, accompanied by diarrhea and vomiting syndrome.

Side effect:

Antibiotics may cause allergic responses in the form of rhinitis, flushing (local redness) of the skin, angioedema, conjunctivitis, urticaria. Occasionally during treatment developed anaphylactic shock , Eosinophilia, serum sickness, fever and arthralgia. Tablets Phenoxymethylpenicillin may trigger the development of leukopenia, pancytopenia, hemolytic anemia , Thrombocytopenia and agranulocytosis. The digestive tract: vesicular cheilitis   (caused by the irritant effect of the active ingredient on the mucous wall), stomatitis, glossitis, dyspepsia (diarrhea syndrome, vomiting, epigastric discomfort and nausea), dry mouth, taste perversion of perception, loss of appetite, pseudomembranous enterocolitis   (rare). The treatment may develop pharyngitis, vasculitis, interstitial neuritis . Reviews on Phenoxymethylpenicillin show high efficacy of antibiotics in the treatment of many infectious diseases, and its good tolerability in compliance with the requirements and recommendations of the attending doctor.

Mode of application:

Tablets Phenoxymethylpenicillin taken one hour before meals, drinking plenty of fluids. Antibiotic regimen for adults and children over twelve years: 3-4 times daily 500-1000 mg (1 mg contains 1610 IU). Patients with severe renal system is recommended to take the medication at intervals of not less than 12 hours. The duration of therapy dentists on average 5-7 days. In the treatment of infectious diseases caused by beta-hemolytic streptococcus   course of antibiotic treatment is recommended to continue for three days after the stabilization of body temperature (average of 7-14 days). Suspensions and solutions intended for use in pediatric patients. Preventing attacks and small chorea rheumatic fever   achieved twice-daily 500 mg of the drug. Prior to surgery to prevent infectious complications administered 2000 mg of antibiotic, every 6 hours 500 mg within two days.

Special instructions:

Analogs of the drug Phenoxymethylpenicillin: Variolar . Kliatsil . Vepikombin . Megatsillin yelling   (coincidence on the active component). If in the first days of therapy and throughout the course of the use of antibiotic-resistant been heavily flowing diarrhea with dehydration, the attending doctor will need to conduct additional diagnostics to exclude the diagnosis " pseudomembranous colitis ". Long-term use of medication, as well as his re-appointment in the short term may lead to the development of superinfection . Price Phenoxymethylpenicillin preparation varies depending on the pharmaceutical network (an average of no more than $ 100).

Drug Interactions:

Phenoxymethylpenicillin reduces the effectiveness of oral contraceptives and medicines, which is formed in the metabolism para-aminobenzoic acid . The opposite effect is observed in concurrent therapy indirect anticoagulants . Treatment of ethinyl estradiol significantly increases the risk of bleeding "breakthrough" . When receiving allopurinol increases risk of allergic response in the form of skin rashes. Phenylbutazone, diuretic drugs, non-steroidal anti-inflammatory agents enhance the antibiotic levels in the blood by reducing the renal tubular secretion. Food, laxatives, antacids, aminoglycosides, Glucosamine   reduce the quality and rate of adsorption. The opposite effect is recorded upon receipt of ascorbic acid. Synergism observed while taking penicillin and bactericidal antibiotics   (number of cephalosporins . vancomycin . rifampicin . cycloserine ). Antagonism action indicated for the treatment of bacteriostatic antibiotics ( lincosamides . macrolides . tetracyclines . chloramphenicol ).