Description overdue on 03/27/2013

Antibiotic . Combined tool whose main components are: sulbactam   (an inhibitor of of beta lactamases) and ampicillin (a semisynthetic penicillin an antibiotic). The drug has a wide spectrum of antimicrobial effects, are acid. The principle of operation is based on blocking synthesizing peptidoglycan component located in the cell wall of bacteria. The main impact has antibiotic ampicillin, which breaks down beta-lactamases. Sulbactam (second component drug Sultasin) allows to inhibit the action of beta-lactamases, which makes ampicillin resistant and more efficient. The antibiotic effect on Gram-positive flora, Enterobacteriaceae, Neisseria, streptococci , Peptokokki, Proteus, klebsiely, clostridia, Enterobacteriaceae, Escherichia coli, grimotritsatelnye microorganisms. Sultasin does not affect the Pseudomonas aeruginosa , Penitsillinazoprodutsiruyuschie staphylococci. The drug is available as a powder, lyophilizate.

Indications:

The antibiotic prescribed for Sultasin bacterial infections   various localization caused by susceptible to the action of microorganisms ampicillin. Respiratory system:   chronic bronchitis, lung abscess, pneumonia, pleural empyema. ENT organs: otitis media, tonsillitis, sinusitis. Urogenital:   endometriosis, cystitis, pyelitis, pyelonephritis , Prostatitis, urethritis . Soft tissue and skin:   dermatitis (secondarily infected), impetigo, erysipelas. Bile duct: development of the cholangitis, the formation of cholecystitis either exacerbation of chronic process. Gastrointestinal tract : Salmonellonositelstvo, salmonellosis , Dysentery. The drug is prescribed for peritonitis, infection of the bones and joints, with gonococcal infections, scarlet fever,   bacterial endocarditis , For the prevention of of postoperative complications after carrying out of of operative interventions on the organs of small pelvis, the abdominal cavity.

Contraindications:

Sultasin during pregnancy, severe liver disease, renal system used with caution. Instructions for use of the drug is not recommended for Sultasin medication intolerance sulbactam and ampicillin, breastfeeding, infectious mononucleosis .

Side effect:

Hemostatic system, organs of hematopoiesis : Reduced number of platelets, white blood cells, severe anemia. The digestive tract:   rarely develops in the background of treatment Sultasin   pseudomembranous enterocolitis , There is vomiting, nausea, and increased liver enzymes. Nervous system:   headaches, slight indisposition, hypersomnia. Allergic responses:   conjunctivitis, rhinitis, angioedema, urticaria, anaphylactic shock, eosinophilia, fever, redness of the skin, arthralgia, anaphylactic shock . In intramuscular medication celebrated light soreness at the injection site; with intravenous drug rarely develops phlebitis . Long-term therapy may lead to the development of candidiasis, superinfection.

Mode of application:

Sultasin administered intramuscularly, intravenous drip. Uncomplicated gonorrhea:   singly 1, 5 g Treatment of infectious diseases:   1, 5-3 grams per day (2 administration). Prevention of surgical infections:   during anesthesia is administered 1, 5-3 grams; after surgery every 6-8 hours antibiotic administered at the same dose.

Special instructions:

The price of the drug Sultasin varies depending on the network of pharmacies (to an average of $ 100). Course therapy is required to carry out under the supervision of the performance of the liver, kidney, organs of hematopoiesis. In patients suffering from hypersensitivity to penicillins observed cross allergic reactions against cephalosporins. Superimposed infection may develop due to growth insensitive microflora, in this case need to replace antibiotic. Jarisch-Herxheimer (bacteriolysis) may develop in patients with sepsis. Analogs of the drug Sultasin: unazin, Sulbatsin, Ampisid   and Sulatsillin. Buy Sultasin possible at a pharmacy without a doctor's prescription of mandatory submission form.

Drug Interactions:

Antibiotic incompatible with   aminoglycosides , Protein hydrolysates, blood products. Food, laxatives, Glucosamine , Antacids, aminoglycosides are able to reduce the quality and speed   Absorption , The opposite effect is observed at taking ascorbic acid. Synergistic effect observed against rifampicin, vancomycin, cycloserine, cephalosporins, aminoglycosides and other bactericidal antibiotics. The antagonistic effect is observed in respect of chloramphenicol, macrolides, sulfonamides, tetracyclines, lincosamides and other bacteriostatic drugs. Sultasin decreases   prothrombin index , Synthesis vitamin K, suppresses intestinal microflora, raises efficiency anticoagulants , The opposite effect is observed when taking oral contraceptives and other medicines, which are formed by the metabolism of PABA. NSAIDs, phenylbutazone, allopurinol, diuretics enhance antibiotic levels in the blood. Risk of skin rash increases with concurrent therapy with allopurinol.