Description overdue on 05.03.2012

Combination antibiotic . The active components are oxacillin and ampicillin. The drug is is active against a gram-positive of flora, Gram-negative microorganisms. Oxacillin is a semisynthetic, penitsillinazaustoychivym antibiotic. Ampioks produced in the form of capsules, powder, lyophilizate.

Indications:

Ampioks prescribed for bacterial lesions: sore throat . pneumonia . sinusitis . bronchitis . otitis media . cholecystitis . cystitis . gonorrhea . pyelitis . pyelonephritis . impetigo . dermatosis . mug . The drug is indicated for the prevention of postoperative, infectious complications in surgical interventions. The drug is effective in the post-natal infections meningitis . sepsis . endocarditis .

Contraindications:

Ampioks not prescribe intolerance ampicillin, oxacillin, penicillin. Drug is contraindicated in infectious mononucleosis , Lymphocytic leukemia.

Side effect:

Ampioks can cause angioedema, hives , Fever, konyunktivit , Rhinitis, eosinophilia, arthralgia , Superinfection, change in taste, dysbiosis , Diarrhea, pseudomembranous enterocolitis , Anemia, neutropenia. When vnutrivennom antibiotics may develop periflebita   and phlebitis; intramuscular injection, tenderness, infiltrate. With the development of anaphylactic shock is administered steroids, epinephrine, antihistamines, mechanical ventilation.

Mode of application:

Oral forms Ampioks: daily dosage is 2-4 grams, the duration of treatment up to two weeks. The daily dose of antibiotic should be divided into 6 stages. Parenterally administered to adult 3-6 grams, divided into 4 doses. Intramuscular administration of vial contents must first be dissolved in water for injection 2 ml or 5. When intravenous drug Ampioks dissolved in sodium chloride, water for injection 10-15 ml. Prepared solutions do not store, use as soon as possible after dilution.

Special instructions:

Heading therapy requires monitoring of the state of the kidneys, the blood, the liver system. It is necessary to consider the possibility of superinfection. In patients with an allergy to penicillin at high risk of allergy, cross reactions when administered cephalosporins. According to the testimony antimicrobial Ampioks prescribed during pregnancy. Low concentrations of the drug are excreted in breast milk, which requires the termination of feeding during therapy. In patients with renal disease is a high risk of nervous system toxicity.

Drug Interactions:

Laxatives, Glucosamine , Antacids, aminoglycosides , Food reduced the rate and completeness of absorption of the antibiotic. When concomitant administration of ascorbic acid recorded the opposite effect. Synergistic effect observed in the appointment of bactericidal antibacterial agents; antagonistic action - with the introduction of bacteriostatic agents. Ampioks improves anticoagulants   indirect action. In the appointment of allopurinol   increases the likelihood of skin rashes.