Description overdue on 07/11/2013

Antibiotic . Active Ingredient - Amoxicillin . Principle effects aimed at inhibiting transpeptidase, to suppress the generation of peptidoglycan (an important component of the cell wall) during growth and division, which causes the death of the bacterial cell. The drug is bactericidal effect. Microorganisms capable of producing penicillinase resistant to the active ingredient. The drug affects the Salmonella , Shigella, Neisseria, streptococci Aerobic gram-positive strains, Gram-negative bacteria staphylococci . As bifidogenic factor in a formulation used lactulose   (polysaccharide synthetic origin), in the molecule which are the remains of fructose and galactose. This polysaccharide is not capable of self-absorbed from the stomach and upper gastrointestinal tract, so lactulose is not hydrolyzed. Ekobol comprises a polysaccharide, which stimulates the development and growth of lactobacilli and bifidobacteria. Under the action of the medicament is enhanced formation of organic acids in the lumen of the colon. Acetic, lactic, formic acid, suppress the growth of pathogens in the gut and reduce the absorption of toxic nitrogen compounds. Thus, the polysaccharide lactulose, intestinal microflora protects against the adverse effects of antibacterial agents amoksifillina. Buy Ekobol can be in the form of tablets (dosage: 125, 250 and 500 mg). The blister pack of 20 tablets. Price Ekobol depends on the dosage, the region, the pharmacy network.

Indications:

Ekobol prescribed for infectious lesions. Diseases of the digestive tract:   cholangitis, typhoid fever Enterocolitis, cholecystitis. Diseases of the urinary tract:   cervicitis, pyelitis, gonorrhea, urethritis, endometritis , Cystitis. Diseases of the respiratory system, upper respiratory tract:   pneumonia, sinusitis, tonsillitis, otitis media, bronchitis, pharyngitis. Drug Usage Ekobol recommends prescribers when leptospirosis,   impetigo , Roger, dermatosis of infectious origin, with borreliosis, listeriosis, salmonellosis, dysentery. The drug is indicated for prevention of endocarditis.

Contraindications:

Ekobol contraindicated in hay fever, asthma, allergic diathesis If hypersensitivity to amoxicillin, cephalosporins, penicillins, carbapenems. The drug is not prescribed for lymphocytic leukemia, infectious mononucleosis , Breastfeeding, in colitis caused by antibiotics. The drug is not indicated for children up to 3 years. In allergy, the propensity to bleeding, kidney diseases and child bearing Ekobol prescribed after consulting several specialists.

Side effect:

Nervous system:   changes in behavior, anxiety, ataxia , Agitation, depression, convulsions, peripheral neuropathy, confusion, headaches, dizziness. The digestive tract:   perversion of taste perception, nausea, goiter, glossitis,   stomatitis , Increased levels of enzymes ALT, AST, vomiting, pseudomembranous enterocolitis, diarrhea.   Hematopoietic system:   neutropenia, a decrease in the number of white blood cells, anemia, thrombocytopenic purpura . Allergic responses: rhinitis, edema, erythema, flushing, exfoliative dermatitis , Eosinophilia, flushing of the skin, rare - anaphylaxis. Possible tachycardia, superinfection (with immunodeficiency), vaginal candidiasis, interstitial nephritis . Reviews on Ekobol indicate a good tolerability of the drug in pill before or after meal.

Overdose:

Manifested by diarrhea, violation water and electrolyte balance , Vomiting and nausea. Requires gastric lavage, saline laxatives, restoring fluid and electrolyte balance. Good results show hemodialysis.

Mode of application:

Ekobol taken orally. Guided: three times a day at 500 mg. In severe cases, appoint 750-1000 mg per reception. Treatment of acute uncomplicated gonorrhea flow:   mono- 3 grams. Women are required to repeat the course in 2 weeks. Treatment of gynecologic diseases of infectious origin, typhoid and paratyphoid:   three times a day or 1500-2000 mg four times daily 1000-1500 mg. Treatment of leptospirosis:   4 times a day for 500-750 mg, the rate of 6-12 days. Therapy salmonellonositelstva:   three times a day at 1500-2000 mg course 2-4 weeks. For small surgical interventions for prevention endocarditis   1 hour prior to manipulation appoint 3-4 grams of amoxicillin. Chance of readmission after 9 hours. Babies medication reduces the amount of 2 times.

Special instructions:

With the development of resistance to amoxicillin increases the risk superinfection . In such cases it is advisable to replace antibiotics. In patients with bacteremia can develop endotoxic shock . In some cases cross allergic responses recorded with cephalosporins in patients with hypersensitivity to penicillins. When diarrhea is not recommended to combine intake Ekobola with antidiarrheal medicines that suppress intestinal motility. After the disappearance of the main symptoms of an infectious disease is recommended to take amoxicillin for 3 more days. Price Ekobol is 50-100 rubles.

Drug Interactions:

Absorption is reduced when taking Ekobola aminoglycosides . glucosamine , Antacid medications, laxatives. The opposite effect is observed in relation to ascorbic acid. Synergy is registered for the treatment of bactericidal antibiotics (vancomycin, aminoglycosides, rifampin, cephalosporins). The opposite effect - when taking bacteriostatic antibiotic (tetracycline, chloramphenicol, macrolides, sulfonamides, lincosamides). Ekobol reduces production Vitamin K Suppresses intestinal flora increases the effects of anticoagulants Reduces the efficiency of contraceptives Containing estrogen. The concentration of amoxicillin increases by lowering tubular secretion when taking non-steroidal anti-inflammatory drugs origin, phenylbutazone, allopurinol, dureticheskih medicines, oxyphenbutazone and drugs that block the secretion into the renal tubule. In the treatment of allopurinol recorded skin rashes. Ekobol raises absorbability Digoxin . By reducing the clearance enhanced toxic effect Methotrexate .