Description overdue on 08.11.2011

Acid-penicillin antibiotic. The main active ingredient is the current Amoxicillin . Flemoksin soljutab shows bactericidal activity against a broad spectrum of bacteria: Gram-negative flora, gram-positive, Clostridium, Streptococcus, esherihii, helicobacter pylori, moraksella, Vibrio cholerae, Salmonella. The principle of operation is in violation of the synthesis peptidoglycan   during the division and growth of bacteria that leads to lysis of the bacteria. Peptidoglycan is a reference polymer cell wall. The acidic environment of the stomach does not affect the absorption of amoxicillin. It is metabolized in the liver, drug metabolites do not have antimicrobial activity. The maximum amoxicillin concentration in the blood is recorded 2 hours after dosing. Flemoksin penetrates into the bone tissue, sputum, mucous membranes, intraocular fluid, creating the desired concentration of the basic substance. Displays the renal system.

Indications:

Flemoksin soljutab prescribed for infections caused by microorganisms that are sensitive to amoxicillin. The sensitivity is determined by seeding bioliquids on nutrient media. The drug is effective in infectious diseases of the gastrointestinal tract, skin, soft tissue, respiratory, genito-urinary organs. GI : salmonellonositelstvo . cholangitis . peritonitis . dysentery . salmonellosis . cholecystitis . Skin and soft tissue: impetigo . mug . Medicine   (secondarily infected). Respiratory : pneumonia . bronchitis . Genitourinary organs : pyelitis . pyelonephritis . cystitis . endometritis . gonorrhea . cervicitis . ENT organs : tonsillitis . pharyngitis . sinusitis Acute middle otitis . Meningitis . leptospirosis . Lyme disease . listeria . sepsis , Prevention of sepsis. Flemoksin approved for use in pregnant women. The main ingredient of the drug passes into breast milk, which should be considered for the prevention of allergic reactions in children.

Contraindications:

Flemoksin soljutab not prescribed for infectious mononucleosis , Leukemoid reactions of the lymphatic type, allergies, severe renal insufficiency system, breastfeeding.

Side effect:

GI : Dyspepsia, dysbiosis . diarrhea , Change in taste, glossitis . stomatitis . pseudomembranous enterocolitis , Increased liver transaminases, vomiting. Nervous system : Ataxia, anxiety, agitation, insomnia, depression, headaches, epileptic reactions, confusion, peripheral neuropathy, a change in behavior. Allergic reactions : Angioedema, urticaria, erythematous rash, conjunctivitis, rhinitis, flushing of the skin.
Forming Organs : Thrombocytopenic purpura, neutropenia , Leukopenia, anemia. It is also noted interstitial nephritis, superinfection, tachycardia, shortness of breath, vaginal candidiasis .

Mode of application:

Flemoxin Solutab taken 30 minutes before a meal or after a meal. The pellet is washed down with the required amount of liquid. Lung infections, moderate require weeks of treatment. Heavier embodiments antibacterial drug treated 2 weeks. After the disappearance of the main signs of infectious disease Flemoksin take another 2 days. The drug is taken three times a day for 0, 5 g In severe cases, the dose was increased to 0, 75 g

Overdose:

Characterized by impaired water and electrolyte balance, dyspeptic disorders. Required hemodialysis The introduction of adsorbents are effective saline laxatives .

Special instructions:

A course of treatment with Flemoksin soljutab control requires monitoring of the blood, liver and kidney systems. With the development of superinfection need to change the tactics of antibacterial therapy. In rare cases, patients with sepsis develops Jarisch-Herxheimer   (bacteriolysis). When oral contraceptives during the treatment period is recommended to use additional methods to prevent unwanted conception.

Drug Interactions:

Flemoksin incompatible with aminoglycosides . Glucosamine , Antacids, laxatives reduce the absorption and ascorbic acid on the contrary, it increases. Macrolides, tetracyclines , Lincosamides, chloramphenicol, sulfonamides are antagonists for flemoksin. Cephalosporins , Aminoglycosides, rifampicin . vancomycin   have a synergistic effect. The drug improves the efficiency of the effect of indirect anticoagulants, increases toxicity and decreases clearance Methotrexate . When concomitantly enhanced absorption Digoxin . Allopurinol , Phenylbutazone, diuretics, NSAIDs increased drug levels in the blood. Allopurinol can cause skin rashes.