Description overdue on 04.03.2013

Antibiotic polycyclic structure . The main ingredient - fusidic acid . The drug acts bacteriostatic against staphylococci , Korinobaktery, streptococci , Neisser. The medicament does not act on proteas, salmonella, Escherichia coli, mushrooms, protozoa and gram-negative microorganisms. Fucidinum T further contains in its structure glucocorticosteroid is hydrocortisone. The medicament is discharged in the form of gel, ointment, lotions, suspensions, granules and tableted dosage form.

Indications:

Drug Usage Fucidinum recommends prescribers ulcerative lesions and infected skin, bruises, burns, gidradenity, pyoderma Impetigo, sycosis, abrasions   (gel, cream and mez). The oral form of the drug is prescribed for Fucidinum osteomyelitis, otitis, pleural empyema , Lung abscess, pneumonia, bacterial endocarditis , Sepsis, infection of skin and soft tissue. Fucidinum T is prescribed for chronic simple herpes, eczema, discoid lupus erythematosus , Atopic dermatitis, neurodermatitis limited, dermatitis (allergic, simple, seborrheic, contact).

Contraindications:

Cream Fucidinum not prescribed for perioral dermatitis, syphilis, fungal and viral skin lesions, intolerance fusidic acid pink acne, primary bacterial skin diseases. In pregnancy, breastfeeding preparation should not be applied to large surfaces. The drug is not prescribed for giperprotrombinemii , Obstruction of the bile ducts, severe liver disease.

Side effect:

Vomiting, epigastric pain , Allergic reactions, diarrhea, nausea, belching, reversible jaundice , Acute hepatic failure of the system (with jaundice). Perhaps the development and periflebita phlebitis   in intravenous injection. Fucidinum ointment can cause flushing, itching.

Mode of application:

Cream Fucidinum put a thin layer to the affected skin after prior removal of necrotic and purulent mass medication is used 1-2 times a day. In case of burns ointment Fucidinum   applied 2-3 times a week. The course of treatment is 7-14 days in average, and depends on the severity of the disease, the form of pathology. Peroral forms: adults appoint thrice a day on the 0, 5 gram of. In severe cases, the first day of fusidic acid dose was increased to 2-3 grams (with a gradual decrease). When osteomyelitis average course of therapy lasts 2-3 weeks. From powder prepare grouts for intravenous infusions, diluting preparation in chloride sodium 0, 9% to a concentration 2mg / ml. The daily dose of fusidic acid is administered in 2-3 doses (vzsrolym - 1 5 grams), the infusion rate of 10-15 drops per minute. Upon completion of the infusion intravenously pour 30-50 ml of sodium chloride. The course of treatment is 3-5 days with gradual transition to oral forms of the drug Fucidinum.

Special instructions:

Fucidinum a reserve antibiotic in infectious diseases caused by penicillin-resistant microorganisms. When the need for long-term therapy in severe disease Fucidinum recommended to combine with tetracyclines, semi-synthetic penicillins. Responses to the drug Fucidinum show good efficacy of medication.

Drug Interactions:

Cholestyramine is able to reduce the level of fusidic acid in the plasma. Antacid medicines reduce the rate of absorption of the drug. A synergistic effect was observed with respect to tetracyclines, macrolides, penicillin, chloramphenicol, aminoglycosides. Efficacy reduce Fucidinum fluoroquinolones Beta-lactams and glycopeptides (mutual effect). A drug capable of potentiating effect of rifampicin in the treatment of diseases caused by certain strains. Fusidic acid is pharmaceutically compatible with carbenicillin, vancomycin , Kanamycin, gentamicin . Drug Interactions drug Fucidinum studied enough, evidence is mixed.