Description overdue on 01.03.2013

Semisynthetic antibiotic. According to the group membership is ansamycins. The active component acts rifamycin . The basic substance is anti-TB drugs   first line. Otofa has a wide range of exposure. At the bacteria medication affects bactericidal. According to the mechanism of action relates to the synthesis of specific inhibitors of ribonuclease. Ear drops Otofa able to exert an antibacterial effect on the extracellular and intracellular located bacteria ( gonokokki , Pneumococci, esherihiya coli, Proteus, Streptococcus, meningococcus). The predominant activity is observed against Mycobacterium tuberculosis. High drug concentrations affect Gram-negative flora . The use of antibiotics as monotherapy leads to the rapid development of resistant strains, and therefore limit the courses of antibiotic therapy 5-6 days. Before the start of treatment is recommended to perform Otofa antibiotikogrammy . The drug acts on microbial strains resistant to cephalosporins   and semisynthetic penicillins . Otofa available as ear drops.

Indications:

Instructions for use ear drops Otofa recommends prescribers when otitis (acute and chronic), and perforation of the eardrum , Purulent isolated membrane lesions. The drug is prescribed after surgery on the middle ear.

Contraindications:

Otofa does not apply in case of intolerance rifamycin.

Side effect:

Ear drops Otofa can cause allergic reactions. Drug Usage Otofa contains information that is observed during treatment with the color change of the tympanic membrane (if otoscopy   notes pink hue).

Mode of application:

Otofa applied topically. You can use the solution to wash tympanum   using a special cannula attic. Adults   drug instilled three times a day, 5 drops of each external auditory canal. Babies   a one-time amount of the drug is reduced to three drops, use of the multiplicity stored as adults. The duration of antibiotic therapy with Otofa is 5-6 days.

Special instructions:

The bottle with the solution before use rifamycin warmed to room temperature .  Using a cold solution causes discomfort in the ear canal .  The drug is able to leave the difficult stains on fabrics and garments, and therefore it is recommended to avoid contact with clothing .  Clinical studies on the safety of treatment Otofa pregnant and lactating women have not been conducted .  Responses to the drug Otofa demonstrate high efficiency of medication in the treatment of ENT diseases .  The price of the drug Otofa varies depending on the pharmacy chain (the average cost is 200 rubles) .  The medicament is discharged in special bottles of 100 ml, which contained 2, 6 grams sodium rifamycin .  Vials containing 10 ml pipette solution .  The drug in its composition contains sulfites, ascorbic acid, macrogol, purified water, potassium metabisulfite, sodium edetate, lithium hydroxide .  Otofa drug should be stored at a temperature not exceeding 25 degrees Celsius .  Keep away from children .

Drug Interactions:

Pharmaceutically significant drug interaction Otofa with other medicines have been registered.