Description overdue on 06/24/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications tsifran
• Contraindications
• Side effects
• Instructions for use tsifran (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• With alcohol
• Reviews
• Price, where to buy

Composition

One tablet contains 250, 500 or 1000 mg of active ingredient ciprofloxacin . Additional material : talc, hydroxypropylmethylcellulose, sodium alginate, magnesium stearate, crospovidone, colloidal silica anhydrous basis, sodium.

TSifran CT   further comprising 600 mg tinidazole .

100 ml of a solution containing 200 mg of ciprofloxacin lactate.

Product form

The drug is available in tablet form and in solution form.

Pharmacological action

TSifran, an antibiotic or not?

Yes, the principle of antimicrobial effects   based on prevents bacterial growth that leads to the death of microorganisms. The drug acts on Gram-positive bacteria   and Gram-negative flora Resistant to aminoglycosides , Penicillin and cephalosporins . The antimicrobial effect is observed in all organs and systems, suppressing inflammation and infectious process that allows you to use an antibiotic for toothache.

The active ingredient in the formulation is Tsiprolet Ciprofloxacin So actually Tsiprolet   and TSifran same for pharmacological action.

TSifran OD   - A long-acting extended-release ciprofloxacin.

Pharmacodynamics and pharmacokinetics

In regard to gram-negative flora   manifests a bactericidal (kills) the effect of a phase of division and the rest (the active substance affects the enzyme DNA gyrase, and causes death, lysis). In gram-positive flora TSifran 500 takes effect only during division. The missing enzyme macroorganism DNA gyrase It is making ciprofloxacin low toxicity to humans. Parallel development of resistance to other antimicrobial drugs ( tetracyclines . aminoglycosides ) During treatment was observed. Resistance is formed very slowly.

Indications tsifran

From what TSifran pills? The drug is prescribed for bacterial infections Caused by microorganisms that are sensitive to the antibiotic ciprofloxacin.

Diseases of the respiratory system:

• cystic fibrosis ;
• pneumonia;
• bronchitis (acute and chronic);
• bronchiectasis .

ENT diseases:

• tonsillitis;
• otitis media;
• sinusitis;
• sinusitis ;
• pharyngitis.

Diseases of the urinary tract:

• adnexitis;
• cystitis;
• pyelonephritis;
• endometritis;
• salpingitis;
• gonorrhea;
• chlamydia;
• oophoritis;
• tubular abscess;
• chancroid.

Infections of the abdominal cavity:

• cholera;
• typhoid fever;
• shigellosis;
• peritonitis;
• salmonellosis.

From what can still be assigned TSifran: burns, abscess, septic arthritis . osteomyelitis . infected ulcers .   sepsis .

TSifran CT   prescribed for heavily flowing mixed infection : empyema . sinusitis . bedsores . dysentery .

Contraindications

• intolerance active ingredient ciprofloxacin;
• vynashivanie pregnancy ;
• lactation .

When mental illness expressed atherosclerotic changes in the brain, epileptic syndrome, renal pathology of the drug is prescribed with caution, weighing the possible complications and expected outcomes. It is not recommended to use for elderly persons.

Side effects (adverse reactions)

Cardiovascular system:

• drop in blood pressure;
• heart palpitations;
• arrhythmias.

The digestive tract:

• cholestatic jaundice (more common in susceptible individuals);
• violation of appetite;
• diarrheal syndrome;
• nausea;
• epigastric pain;
• gepatitgepatonekroz .

Nervous system:

• anxiety;
• headache;
• fatigue;
• sleep disorders;
• peripheral paralgeziya   (violation of the perception of pain);
• rash;
• various psychotic reactions.

Senses:

• violation of auditory perception;
• noise in ears;
• impaired color perception, diplopia ;
• taste perversion.

Urinary tract:

• crystalluria ;
• hematuria;
• dysuria;
• glomerulonephritis;
• interstitial nephritis.

Possible allergic response in the form of urticaria, drug fever, epidermal necrolysis . Rarely recorded   myalgia , Arthralgia, tendon rupture, changes in the blood.

Instructions for use tsifran (method and dosage)

How to take the drug:   to increase the bioavailability of strongly advised to take the tablets on an empty stomach. During the entire period of treatment required increased use of water. Infusion administering intravenously a solution is possible only for 0, 5-1 hours.

Treatment of uncomplicated urinary tract pathology:   every 12 hours, 250 mg.

Treatment of prostatitis, severe diseases of the urinary system: twice daily at 500 mg.

Treatment of ENT diseases, respiratory system diseases, typhoid fever:   500 mg every 12 hours. In severe cases, parenterally administered drug recommended by the scheme: 200 mg (100 ml vial) was slowly intravenously twice a day (single dose may be increased to 400 mg).

Instructions on TSifran ST: Tablets should be taken after a meal, without destroying the integrity of the containment. Recommended dosage -250 \ 300 mg (ratio of active substances ciprofloxacin and tinidazole) twice a day, 2 tablets.

Instructions for use TSifran OD: the medication on an empty stomach accelerates anti-bacterial effect. Recommended regimen: 250 mg 2-3 times a day.

Overdose

High doses of the medication increase the severity of adverse reactions. It is recommended that induction of vomiting, adequate hydration Holding posimptomnoy therapy. No specific antidote developed.

Cooperation

The level of theophylline is increased while treatment ciprofloxacin . It recommended withstanding 4-hour window between doses tsifran and preparations containing zinc, iron, magnesium, sucralfate, aluminum. Anti-inflammatory, non-steroidal agents enhance the stimulating effect of medication on nervous system . It requires mandatory monitoring coagulation while taking warfarin.

Terms of sale

The Holiday prescription form .

Storage conditions

In the dry mode, the temperature - 25 degrees.

Shelf life

2 years. When precipitation in a solution of medication found to be unsuitable.

Cautions

To prevent crystalluria requires an adequate fluid intake during treatment. It is recommended to avoid sun exposure .

Analogs tsifran CT

Substitutes have a combined preparation TSifran CT   no. Analogues of drugs TSifran: Tsiprinol . Tsiprobay . Tsiprolet .

Compatible with alcohol

Record the slowing of psychomotor reactions. Alcohol increases hepatotoxic effects   medicament.

Reviews on TSifran

Medical portals and forums contain only positive feedback about the drug.

Reviews on TSifran OD   characterize medicine as a highly effective broad spectrum antibiotic with good tolerability.

Reviews on TSifran CT   show the effectiveness of the drug in the treatment of dysentery and diarrhea syndrome.

Price TSifran where to buy

The cost of medication is determined by the region in sales and a dose of the active substance. The price of the tablet TSifran OD   1000 mg in Moscow is 300 rubles. Price TSifran CT   500 mg - 350 rubles. The minimum price for the antibiotic is 180 rubles. Find out how much preparation and you can buy it at any pharmacy in your area.