Description overdue on 05.03.2012

Antibiotic . It is used parenterally and orally. The active ingredient is a second-generation cephalosporin - cefuroxime . The mechanism of action is aimed at violation of of the process of synthesizing in the wall of the bacterial cell. Zinnat acts germicidally, active against strains which resistant to penicillin antibiotics. The drug is available in the form of granules, powder, tablets.

Indications:

Zinnat is prescribed for bacterial infections: lung abscess . bronchitis . empyema . pneumonia . otitis . furunculosis . pharyngitis . gonorrhea . tonsillitis . sinusitis . asymptomatic bacteriuria . cystitis . pyelonephritis . impetigo , Erysipelas, phlegmon, abrasions, septic arthritis, osteomyelitis . The drug is effective in pelvic pathology: cervicitis , Adnexitis, endometritis . The drug is prescribed for meningitis, sepsis, borreliosis, to prevent infections after surgery.

Contraindications:

Zinnat is not indicated during breastfeeding, hypersensitive to carbapenem, cephalosporin, penicillin. In the pathology of the digestive system, bleeding, premature infants and newborn babies, pregnancy, decreased immunity the drug is prescribed with caution.

Side effects and overdose:

Zinnat may trigger the development of allergies, bronchospasm . anaphylactic shock , Stevens-Johnson syndrome. At the injection site may occur   phlebitis , Infiltration, pain and irritation. Genito-urinary system : vaginitis Itching in the perineum, dysuria, irregularities in the renal system. Alimentary tract : Abdominal cramps, vomiting, diarrhea, nausea, pseudomembranous enterocolitis . candidiasis   mouth. Nervous system : Convulsions. Perhaps the development of hemolytic anemia , Hearing loss, increased liver enzymes, hyperbilirubinemia . In overdose recorded stimulation of the nervous system, convulsions. It is recommended to conduct peritoneal dialysis, hemodialysis, support vital body functions.

Mode of application:

Zinnat administered intramuscularly, intravenously, orally. Adults parenterally administered 750 mg three times a day. In severe infectious disease dosage may be increased to 1500 mg. The average dose for adults up to 6 gram of. In gonorrhea Zinnat is administered intramuscularly, once in an amount of 1500 mg. In bacterial meningitis - every 8 hours for 3 grams. When pneumonia - 2-3 times a day, 1500 mg intramuscularly, intravenously, after which the diagram change: during the week is administered at 500 mg twice a day.

Special instructions:

In persons who are prone to allergic reactions to penicillin may develop intolerance to antibiotics, cephalosporins. Antibiotic therapy requires regular monitoring over the work of the renal system. During treatment possible false positive reaction for glucose in the urine, and false-positive direct   Coombs' test . The prepared solution can be stored at room temperature for more than seven hours, and 48 hours - the refrigerator. Yellowing solution is considered suitable for use.

Drug Interactions:

"Loop" diuretics are able to slow down tubular secretion Reduce renal clearance, increase half-life of the drug Zinnat raise its concentration in the blood. Diuretics and increase the likelihood of aminoglycosides nephrotoxic effect . Zinnat incompatible with sodium chloride, lidocaine, dextrose solution, Hartman solution, Ringer Heparin.