Description overdue on 05/20/2013

Antifungal agent.   High concentrations of active ingredient have fungicidal effect   on fungi, and in small doses, the drug acts fungistatically. The main component acts clotrimazole . The active substance is a derivative of an organic compound of imidazole. The drug is used vaginally, topically, topically. The active ingredient is slowing synthesizing enzyme ergosterol   (one of the components of microbial cells), which ultimately changes the properties and structure of the microbe. Antifungol active against gram-negative flora, pathogens multi-colored lichen, molds Pathogenic dermatophytes, a gram-positive flora, yeasts,   Trichomonas , Pathogens erythrasma. The fungicidal concentrations medicament reacted with peroxidase enzymes and mitochondrial components that increases the level of hydrogen peroxide to toxic to fungal and microbial indicators. Antifungol available in tablet form (intravaginal administration), ointments, powders, solutions, lotions. One tablet contains 500 mg of active ingredient clotrimazole. Included with the product is the introduction of a special applicator for vaginal tablets.

Indications:

Antifungol ointment prescribed for fungal diseases of the skin and mucous membranes: microsporia , Athlete, tinea , Dermatomycosis, trichophytosis, a fungal paronychia, a fungal erosion of interdigital folds, stomatitis , Candidiasis, balanitis, vulvovaginitis, erythrasma, pityriasis versicolor, candidiasis vulva, colorful versicolor. Antifungol recommended for use before delivery for the purpose of redevelopment of the birth canal.

Contraindications:

Candles antifungol not indicated in the menstrual period, during gestation pregnancy, intolerance of clotrimazole. When feeding-FEEDING to young mums the medicament appoint with caution, Commending the the potential risk.

Side effect:

Ointment antifungol can cause paresthesia , Swelling, peeling, irritation, rash erythematous, burning, appearance blisters . Because of possible allergic reactions and itching rash. Intravaginal use may be accompanied by specific vaginal discharge, edema and hyperemia of the mucous walls, burning, itching, gastralgia, pain during intercourse, frequent urination, and possibly development intercurrent of cystitis .

Mode of application:

Drug Usage antifungol. It is recommended to apply solution of, lotion, ointment and a cream a thin layer of on the affected by a fungus mucous wall and plots of integuments 2-3 times a day; medication can be rubbed neat movements. The calculation of the amount of the drug: processing site, the size of a palm, it takes about 20 drops of a solution or clotrimazole cream column length of 0, 5 centimeters. Duration of antifungal therapy makes approximately 3 weeks; after the disappearance of symptoms of fungal infection treatment is recommended to continue for another 2-weeks. Treatment erythrasma   It is 2-4 weeks. Therapy multi-colored lichen   It lasts about 1-3 weeks. Stops before treatment is recommended to wash with warm soapy water, wipe with special attention interdigital spaces. After reaching the desired effect antifungal therapy is recommended to continue for 2-3 weeks. Vaginal form of preparation (gel and cream) must be inserted deep into the vagina 1 to 5 grams per day; therapy designed for 1-2 weeks. Sanation of patrimonial ways : A single injection into the vagina 1 vaginal tablet. Treatment candidiasis   vagina: by 200 mg within three days, either singly 500 mg, or within 6-7 days from 100's mg. Be sure to conduct processing of the external genitalia. Treatment urethritis : Instillation into the urethra 1% solution; therapy designed for 6 days. Not recommended the abolition of the independent clotrimazole without consulting a doctor.

Special instructions:

Treatment trichomoniasis It must be accompanied by additional intake of chemotherapy medications (eg oral metronidazole) .  Not recommended the imposition of occlusive dressings on the treated areas of the skin and mucous walls .  Vaginal applicators in exceptional cases may be used in the second and third trimester of pregnancy .  Simultaneous antifungal and antimicrobial therapy of both sexual partners to prevent reinfection .  With the ineffectiveness of ongoing antifungol antifungal therapy for 4 weeks ex conduct additional methods of inspection to determine the cause of the disease, infectious agent .  Patients with liver disease need to control the level of bilirubin, ALT and AST enzymes .  With the development of of irritation and hypersensitivity at the application site of medicament of his cancel .  Not allow any clotrimazole on mucous membranes of eyes .  Responses to the drug antifungol indicate good tolerance, high efficiency of medication in the treatment of fungal diseases .  Price antifungol depends on the region and network of pharmacies .  In case of accidental drug ingestion into developing anorexia , Nausea, stomachalgia Vomiting. In rare cases recorded hallucinations , Hypersomnia, disorders of the liver, skin manifestations of allergic response, thamuria . Recommended timely reception Activated Carbon   and supervision of the attending doctor.

Drug Interactions:

Application Nystatin . Amphotericin B , Natamycin or other polyene antibiotics   at the same time reduces the effectiveness of clotrimazole antifungol.