Description overdue on 04/29/2014
- Latin name: Neo-Penotran
- ATC code: G01AF20
- Active substance: Metronidazole (Metronidazole) + Miconazole (Miconazole)
- Manufacturer: Co. Ltd. Embil Pharma for "Sherning AG", Turkey
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Neo-Penotran : metronidazole in the amount of 1/2 r + miconazole nitrate in an amount of 1/10 g + adjuvants ( witepsol of 1, 9 grams).
Neo-Forte Penotran : metronidazole in the amount of 3/4 r + miconazole nitrate in an amount 1/5 r + auxiliaries (witepsol of 1, 5 gram).
Neo-Forte A Penotran : metronidazole in the amount of 3/4 r + miconazole nitrate in the amount of 1/5 r + Lidocaine - Excipients ( witepsol of 1, 44 grams).
Product form
Pessaries, white or yellowish, oval. Batches 7 and 14 pieces.
Pharmacological action
The antimicrobial, antifungal, antibacterial, antiprotozoal facilities.
Pharmacodynamics and pharmacokinetics
The product contains a number of components that have different effects on vaginal microflora . Found in all components of the blood plasma medicament can for 3 days.
Miconazole - Antifungal agent. It inhibits basic livelihoods pathogenic fungi , Is also active in some Gram-positive bacteria . Almost not absorbed into the bloodstream through the mucous membrane.
Metronidazole damaging to Anaerobic bacteria and some protozoa . Affects Trichomonas vaginalis And Gardnerella vaginalis . 20% of the administered dose into the blood. Excreted through the kidneys.
Part Neo-Forte A Penotran further includes Lidocaine Possessing analgesic properties. Within 4-6 minutes after the administration, the substance starts to operate. The substance inhibits the process of nerve impulses through neuronal membrane . Then metabolized in the liver and significantly eliminated via the kidneys.
Indications
Candles Neo-Penotran appoint:
- thrush ( candidiasis vulva and vagina);
- at Trichomonas vaginosis and bacterial vaginosis ;
- topical treatment vaginal infections mixed type.
Contraindications
- drug allergy Substances belonging to the vehicle;
- severe liver and kidney diseases;
- epilepsy and other serious diseases of the central and peripheral nervous system;
- pregnancy (1 term);
- Also, the drug is contraindicated in children under 14 years.
Side effects
In general, the drug has always well tolerated. But there have been cases of allergy, itching and burning in the genital area, pain in the abdomen.
It is rarely possible ataxia, neuropathy, seizures and epilepsy . leukopenia, nausea, vomiting, metallic taste in the mouth, hives .
Instructions for use (method and dosage)
Guide to Neo-Penotran
Vaginal candles injected deep into the vagina at night. 1 thing for 7 days. In severe cases, the treatment may be extended to 14 days.
Instructions Penotran Neo-Neo-Forte and Forte Penotran A
The most common drug prescribed for the 1st suppository at night. Heading 7-14 days. The package, to the drug making fingertips for a single application. They should be used when administered medications to the vagina.
Overdose
Nausea, abdominal pain, vomiting, itching, ataxia, taste of metal in mouth, anorexia, changes in urine color, stomatitis, headache, diarrhea - Symptoms peredozirovki.Esli drug was inside, should wash out the stomach and produce a therapy, according to exhibited symptoms.
Cooperation
You can not combine the drug with ethanol . Action oral anticoagulants . lithium preparations . disulfide . astemizole and terfenadine enhanced.
At reception phenytoin and phenobarbital effectiveness metronidazole decreases. In combination with cimetidine , Increasing side effects.
Terms of sale
It requires a prescription.
Storage conditions
In a dark, cool, the children, the temperature regime - no higher than 25 degrees.
Shelf life
24 months.
Cautions
The drug is not prescribed virgins and children (under 14 years).
At monthly and while taking the drug should consult a doctor. Use candles during menstruation is not recommended.
Analogs Neo-Penotran
Ginalgin
Lomeksin
Ornidazole Vero
Clione-D 100
Gyno-Pevaril
Livarol
Ginezol
Antifungol
Candide
Ginofort
Trichopolum
Flagyl
The closest analogue of vaginal suppositories: Neo-Metromikson (candles also) and Clione-D 100 .
Also analogues of the drug are: Ginalgin, Klomezol, Klevazol, Pulsiteks, Ginofort, Kandibene, Kandisan, Gravagin, ketoconazole, Livarol, clotrimazole, Metrogil Vaginal, Mikogal, Metronidazole, Econazole, Trichopolum .
Price analogues Neo-Forte Penotran It may differ significantly from the original.
With alcohol
The drug can not be combined with alcohol.
When pregnancy
Neo-Penotran during pregnancy in 1 trimester is not appointed.
Your doctor may prescribe a candle Neo-Forte Penotran during pregnancy if the benefit to the mother outweighs the perceived risk to the child.
Reviews on Neo-Penotran
Reviews for candles Penotran Neo-Forte and Forte A generally good. The drug helps a lot when dealing with thrush, especially in the chronic form. Often there is itching and intense burning as a side reaction, but the symptoms pass quickly.
Reviews pregnancy : Women are satisfied with the result of using candles during pregnancy. Most often, the drug does not harm the fetus causes and effectively combats unwanted diseases.
Price Neo-Penotran (Where to buy)
Cost Neo-Forte Penotran - About 800 rubles per 7 pieces. Buy candles №14 Neo-Penotran it is possible for 670 rubles. Cost Candles Neo-Forte A Penotran about 830 rubles per 7 pieces.