Description overdue on 10/24/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use fenigidin (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• During pregnancy (and lactation)
• Analogs
• Reviews
• Price, where to buy

Composition

In 1 tablet is 10 mg of the active ingredient - of nifedipine . Additional components: Tween-80, low molecular weight polyvinylpyrrolidone, potato starch, methylcellulose, acid red 2C, titanium dioxide, sugar (refined and milk).

Product form

The medicament is discharged in the form of a bilayer tablet magenta convex shape. 10 tablets in blister packs of cellular. In 1 carton packaging contains 50 tablets.

Pharmacological action

Active ingredient, as antagonist of calcium ions , Triggers a blockage calcium channels in cells cardiomyocytes and arteries. Thereby, nifedipine affects the heart and peripheral blood vessels, causing their extension. It does not affect on the tone of gladkomyshechnoj musculature veins. This reaction reduces Blood Pressure , Reduce peripheral vascular resistance (mainly arterioles), reduced oxygen demand in cardiomyocytes and, accordingly, all this leads to a significant reduction in the load on the heart as a whole. One function is as nifedipine aggregation inhibition Platelet .

Pharmacodynamics and pharmacokinetics

The medicament is characterized by a fast absorption and fast - a maximum concentration of nifedipine in the blood is recorded after ½ hour while taking per os. Period metabolize and half-life of two to four hours. Highlight products metabolism   It carried out by the kidneys in urine, partially inactive metabolites found in the feces.

Indications

Appointed fenigidin pressure, which is increasing due to the following cardiovascular diseases:

• arterial hypertension ;
• hypertrophic cardiomyopathy;
• Raynaud's disease .

The drug is used for quick relief hypertensive crisis   and prevention of attacks angina   ( ischemia of the heart).

From what fenigidin can still be used? In pulmonology drug prescribed for:

• pulmonary hypertension ;
• broncho-obstructive syndrome .

Contraindications

• reduced systolic blood pressure ( hypotension );
• heart failure   severe;
• collapse ;
• Individual hypersensitivity to the active substance or the like dihydropyridine;
• aortic stenosis ;
• cardiogenic shock ;
• myocardial infarction   in the acute stage;
• period pregnancy   and Lactation .

Side effects

• a sharp drop in blood pressure;
• swelling of the lower extremities ;
• asystole ;
• redness of the breast skin and face;
• tachycardia ;
• bradycardia.

Possible violation of the central nervous system reactions:

• moderate drowsiness ;
• sleep disorders ;
• blurred vision;
• dizziness ;
• tremor of the extremities ;
• migraine headache .

From the digestive tract:

• diarrhea ;
• nausea ;
• heartburn ;
• inhibition of liver function.

Instructions for use fenigidin (method and dosage)

The dosage is determined individually based on several factors (age, concomitant diseases, total body reaction etc.). Typically, the minimum dosage of 10 mg (in some cases, 20 mg), the number of receptions - up to 4 times a day. With stenosis of the coronary arteries minimum dose equal to 50-100 mg. Instructions on fenigidin provides maximum safety the number of pills a day - no more than 12 pieces.

For relief angina attacks   and hypertensive crisis   necessary accept a preparation sublingually until complete dissolution. Additionally, it is recommended to take prone position for at least 1 hour.

No dosage adjustment is carried out with extreme caution, gradually increasing or decreasing the amount of active substance. To avoid side effects, it is desirable to take the medication together with meal.

The course of therapy is determined under indications and usually amounts to 1-2 months. Next the attending doctor selects another scheme of treatment.

Overdose

If overdose occurs dangerous to health decrease in systolic blood pressure. Are observed the following symptoms:

• bradycardia ;
• collapse ;
• hypotension (may lead to loss of consciousness);
• dysrhythmia   and conduction of the heart;
• headache .

If symptoms of poisoning should immediately implement gastric lavage   and take Activated carbon . In severe cases, patients prescribed a 10% solution of calcium chloride intravenously.

Cooperation

The drug has a pronounced effect while taking other drugs to lower blood pressure, nitrates, diuretics, tricyclic antidepressants, Ranitidine . Cimetidine . In combination with   beta-blockers   It can cause poor circulation of the heart muscle, strengthen hypotension.

Reduces the effectiveness of nifedipine when taken with calcium,   Phenytoin . Rifampicin . Phenobarbital . Carbamazepine .

Together with the admission Digoxin . Quinidine   and Theophylline   changing the concentration of the blood plasma. Ethanol can cause an increase in the effect of nifedipine, causing dizziness, weakness, a violation of the coronary circulation.

Terms of sale

Sold in retail points with the mandatory presentation of a prescription.

Storage conditions

The drug should be stored away from young children in a dry, dark place. Optimum temperature - below room temperature (8-15 ° C).

Shelf life

Subject to proper conditions of storage - 3 years.

Cautions

Fenigidin must be used under strict medical supervision, and myocardial infarction, diabetes , Diseases of the liver system, pathology of cerebral circulation, hypovolemia, hemodialysis   - Only in a clinical setting.

The dose is increased and decreased gradually. Abrupt discontinuation of treatment may be dangerous. For elderly recommended dose reduction due to the reduced metabolism. For speedy absorption is recommended to dissolve a tablet under the tongue until completely dissolved. During treatment, no admission of alcohol and substances that reduce blood pressure.

It is not recommended during treatment to manage different types of transport mechanisms and carry out work that requires attention and concentration.

During pregnancy and lactation

Fenigidin not recommended during pregnancy and lactation, since adequate studies in this area have been conducted. Maybe embryotoxic and teratogenic effects   active substance. Nifedipine penetrates the ore milk.

Analogs

There are many unique fenigidin with a similar mechanism of action:

• Nifedipine;
• Cordipin;
• Infarction;
• Nifecard;
• Corinfar.

Reviews fenigidin

Analysis of information on medical portals has allowed to draw a conclusion, that the given preparation is considered obsolete, and the set restrictions on the use forced to of doctors appoint more than safe and modern analogues. Reviews have reported that very often there is the development of side effects. In this regard, many participants forums concerned for their health, but unanimously confirm the effectiveness of this drug, especially during angina attacks and the sharp increase in systolic blood pressure.

Fenigidin differs from other antihypertensive medications presence of additional effects, because the active substance is not only helps to reduce the blood pressure, but also has antiatherosclerotic action.   Opinions of patients at the expense of separated: someone chooses an effective drug for hypertensive crises, turning a blind eye to the severity of side effects, and for some it is preferable to receive safe products of contemporary level that not only gently lower blood pressure, but do not cause adverse reactions.

Price fenigidin where to buy

Fenigidin can buy pharmacy by presenting a doctor's prescription form. The price is an average of 14-31 rubles per 50 tablets and depends on the point of sale.