Description overdue on 06/19/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Fiziotenza (method and dosage)
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Reviews
• Price, where to buy

Composition

Tablets containing different amounts of the active ingredient - moxonidine   - 0, 2; 0, 3, or 0 to 4 mg.

Additionally, the medication contains povidone, hypromellose, lactose monohydrate, ethylcellulose, magnesium stearate, talc, titanium dioxide, Macrogol 6000, E171, crospovidone, E172 . INN: moxonidine .

Product form

The drug is released in the form of round, convex tablet into different colors shell. Tablets of moxonidine 0, 2 mg are pale pink color, with the content of 0, 3 mg - soft red, and 0, 4 mg - Red matte finish. Each tablet marked with the dosage.

Packages 14, 28 and 98 units (14 of one blister pack).

Pharmacological action

Antihypertensives.

Pharmacodynamics and pharmacokinetics

The active substance acts directly on imidazoline receptors CNS   located at medulla . This leads to reduced activity Mr. sympathetic. from. And arterial pressure   decreases.

Due to the fact that the low similarity in imidazole alpha-adrenoceptors Such common side effects as dry mucous membranes and pronounced practically do not arise.

All of the meal, one hour after administration, the highest concentrations of active substance in the blood. About 7% is associated with plasma proteins . In the body, metabolized guanine and 4, 5-digidromoksonidin   (they are output for 5 hours). Self moxonidine displayed per day, in the kidneys.

Pharmacokinetic parameters are changed in liver disease and kidney significantly in the elderly.

Indications

Arterial hypertension.

Contraindications

• Sensitivity and allergy on components within the vehicle;
• heart failure   and bradycardia ;
• children (under 18 years);
• liver and kidney disease;
• sick sinus syndrome .

Side effects

FEATURES:

• dryness of mucous membranes ;
• bradycardia   weakness;
• decrease in blood pressure;
• nausea ;
• allergy skin .

After the first 14 days of dosing the intensity and frequency of the symptoms is reduced.

Instructions for use Fiziotenza (method and dosage)

According to the instructions for use Fiziotenza take pills, regardless of the meal.

The daily dose of the drug is from 0 to 2 0 mg, 6 mg, taken up to 2 times. Max Fiziotenza adopted at a time - 0, 4 mg.

In kidney, the maximum single dose is 0, 2 mg, and the daily - 0, 4 mg.

Cooperation

Not recommended combination with tricyclic antidepressants , Other antigipertezivnymi   means tranquilizers . ethanol   hypnotics   and sedatives means benzodiazepine .

Terms of sale

Prescription.

Storage conditions

In a dark, cool place.

Shelf life

2 years.

Cautions

Effect on the rate of psychomotor reactions   It has not been fully investigated. It is recommended to refrain from driving and other motor vehicles requiring a high degree of concentration of activities.

The most common analogue Fiziotenza a drug called moksogama . It contains the same active ingredient.

Another analogy: tenaksum, clonidine   (of different output), estupik .

Reviews Fiziotenze

Reviews Fiziotenze good. Prolonged continuous reception is effective in reducing blood pressure. Side effects most often - headache, dry membranes of the mouth. The drug most commonly used older people take it for crises, and every day after lunch.

Price Fiziotenza (Where to buy)

The cost for the same amount of 0, 2 mg - 266 rubles.