Description overdue on 16.12.2011

The preparation metazon   It refers to the group alpha-agonists . Its active substance is Phenylephrine . Metazon applied during subduralnogoi inhalation anesthesia, local anesthesia during both vasoconstrictor In acute circulatory failure, neurogenic shock, anaphylaxis . hypotension , Secretory prerenal anurii . paroxysmal supraventricular tachycardia , Reperfusion arrhythmias . iritis . iridocyclitis .

Preparation metazon applied subcutaneously, intramuscularly, intravenously (bolus administered should be slowly or infusion) for intravenous bolus injection of 10 mg metazona dissolved in 9 ml of water. To perform an intravenous infusion of 10 mg metazona added to 500 ml of 0 9% sodium chloride or 5% glucose. At moderate hypotension intravenous 0 2 mg, with between injections must be at least 10-15 minutes. In severe hypotension and shock metazon drug administered intravenously. In paroxysmal supraventricular tachycardia is injected intravenously, and the initial dose should not exceed 0, 5 mg. For exposure metazona as a vasoconstrictor in Regional Analgesia - to anesthesia solution added metazon 1 mg per 20 ml.

Contraindications and side effects:

Do not use the drug metazon people who have been highly sensitive to its components. Also contraindications include severe form hypertension , Ventricular tachycardia, bradycardia A tendency to angiospasm Shock during myocardial infarction. The drug is not used in decompensated heart failure, conduction disorders, atherosclerosis , Severe coronary artery disease, cerebral arterial lesions, acute pancreatitis   and hepatitis . hyperthyroidism . arterial thrombosis Hypertrophy of the prostate. Metazon is contraindicated in pregnant women, children under 15 and seniors.

As a manifestation of the possible side effects of headache, agitation, irritability, feelings of dizziness and weakness, pain in the heart, hypertension . bradycardia . Arrhythmia , Respiratory depression, acidosis . tremor , Local ischemia skin location where injection of necrosis and scab formation, provided the product enters the tissue.

With an overdose of the drug may occur ventricular premature beats   and paroxysms of ventricular tachycardia. Also, there is a heaviness in the head and limbs, a sharp increase in blood pressure. To remove these conditions produced by intravenous administration alpha-blockers   and beta-blockers .

Specific recommendations:

The pressor effects metazona increases if you take it along with Oxytocin , MAO inhibitors, tricyclic antidepressants, ergot alkaloids, simpatomimetikami . Not to be combined with the use of metazona oksitotsinsoderzhaschimi drugs to induce labor. During therapy should be carefully monitored blood pressure, do an electrocardiogram, blood circulation to carry out control, wedge pressure in the pulmonary artery. Before you start treatment metazonom should be adjusted hypovolemia . acidosis . hypoxia . hypercapnia . If during therapy dramatically increased blood pressure, there are cases of bradycardia or tachycardia, arrhythmias, treatment should not continue. It is impossible to engage in detail, coupled with the need to speed reactions and physical activity.