Description overdue on 05/19/2014
- Latin name: Papasolum
- ATC code: G04BE52
- Active substance: Bendazol and papaverine hydrochloride
- Manufacturer: Irbit chemical plant, Medisorb, Dalkhimpharm, Pharmstandard-Tomskhimpharm, Moskhimfartpreparaty them. Semashko, Pharmstandard-Ufa Vitamin Plant, Uralbiofarm (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Papazol
- Contraindications
- Side effects
- Instructions for use Papazol (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One tablet contains the pressure papaverine hydrochloride 0, 3 g, bendazol 0, 3 g + adjuvants ( potato starch, stearic acid, talc ).
Product form
Flat-shaped cylinder white or white and gray with splashes of pills. Papazol release in banks 10, 20, 25, 30, 40, 50 and 60 units and in packages made of cardboard, with or without the cells of 10 pieces. Papazol UBF - In cardboard packs of 10, 20, 30, 50 pieces, in a package with or without cells.
Pharmacological action
Antispasmodics, dilates blood vessels.
Pharmacodynamics and pharmacokinetics
Drug exposure on the body caused by set of two active substances bendazol and papaverine . Papaverine reduces vascular resistance and blood pressure because the blocked enzyme phosphodiesterase and creatine kinase in vessels. The amount of calcium inside the cell decreases, begins to accumulate cyclic AMP This causes vasodilatory effect of the drug. Papaverine has antispasmodic effect on the digestive tract and bile - and the urinary tract.
Bendazol imidazole acts directly on vascular smooth muscle receptor (their walls). Thus, as papaverine, relieves spasms, reduce blood pressure, reduce the number of intracellular calcium. The substance stimulates the activity spinal cord Propafenone and acts as immunomodulator . Intensify the process of protein synthesis, and nucleic acid Working out antibodies and phagocytosis .
Why and what medication is used?
The tool provides vasodilator, antispasmodic, vazodilatatornym . In large doses, it is weakly expressed sedation .
The drug raises or lowers the pressure?
Papazol lowers blood pressure by reducing the resistance of the vessel wall.
Indications Papazol
From what is prescribed the pill?
- of labile hypertension ;
- spasms abdominal organs;
- Bell's paralysis on the periphery;
- spasm of cerebral vessels and arteries.
From what has appointed Papazol?
Also, the indication for use can serve as a residual effects after Polio .
Contraindications
- drug allergy ;
- Respiratory depression and epilepsy ;
- Children under one year;
- AV conduction disorders ;
- liver and kidney disease;
- hypothyroidism, and traumatic brain injury;
- reduction processes intestinal motility Some diseases prostate .
With care prescribe medication in traumatic brain injury, pregnant women and lactating mothers.
Side effects
Nausea, allergies, sweating, constipation and violations in the work of the heart muscle.
Instructions for use Papazol (method and dosage)
How to take the medicine?
Orally. Instructions on Papazol UBF and instructions for use of tablets Papazol point. Generally, a daily dose is from two to six tablets a day, divided into 2-3 doses per day.
Overdose
There are dispeptichnye phenomenon and increased side effects. Treatment - according to exhibited symptoms.
Cooperation
Not recommended combination with adsorbents, binders and enveloping gastrointestinal tract drugs.
Action drug efforts in conjunction with sedatives . tricyclic antidepressants . antispasmodics . novokainamidom . diuretics . reserpine .
The drug weakens anticholinesterase agents . levodopa . neostigmine methylsulfate .
Toxic effects on the liver when used with nitrofurantoin enhanced.
Terms of sale
To purchase a prescription drug is not required.
Storage conditions
In a dark, cool place, not above 30 degrees.
Shelf life
5 years.
Analogs
Zidena
Levitra
Viagra
Impaza
Cialis
Dibazol, duzofarm, enelbin 100 retard Papazol-lhfz, vinoksim mV Papazol-Darnitsa .
With alcohol
Not recommended combination with alcohol.
During pregnancy and lactation
There is an insufficient number of clinical studies for admission Papazol during pregnancy. The drug is prescribed with caution and under the supervision of a physician.
Reviews at pregnancy Well, many have used the drug to reduce the pressure and satisfied with the result.
Reviews Papazol
In various forums on the Internet, there are positive reviews of Papazol. Typically, the drug is used in the pressure. Papazol at elevated pressure helps when it is taken by a doctor and for a long time (from one to five years). Older people with strong and rapid irregular blood pressure medication does not always help.
Price Papazol (Where to buy)
Average price Papazol and Papazol UBF 10 tablets (1 plate preparation) is from 7 to 12 rubles.