Description overdue on 04.12.2011

The drug has a moderate, koronarolitichesky (vasodilator) action . The effect is achieved through stimulation of cold-sensitive receptors located in the oral cavity. Irritation of the nerve receptors has a calming effect on the nervous system. With stimulation of receptors increased production opioid peptides   (enkephalins, endorphins, dynorphin), under the influence of which normalizes vascular permeability, reduces the severity of pain, regulates the operation of the nervous and cardiovascular systems. Korvalment stimulates kininov . histamine   and other physiologically active substances. Antispasmodic, sedative effect is due to the action isovaleric acid , Which is part of the preparation Korvalment.

With sublingual drug adsorption occurs with the oral mucosa. The effective action of the drug is 5 minutes. Biotransformation means carried in the hepatic system, the metabolites are excreted in the form of glucuronide   through the urinary system. Available in a soft, pale yellow spherical capsule inside the capsule contains an oily liquid has a menthol smell.

Indications:

The capsules are prescribed for Korvalment neuroses , Easy to get started angioneurotic angina . functional angina . With air, sea sickness drug is used as an antiemetic. Korvalment relieves headache caused by intake of nitrates.

Contraindications:

Korvalment not prescribed for acute myocardial infarction in acute, severe arterial hypotension, acute stroke. The drug is not used in pediatric patients until the age of 6, when allergy to the components.

Side effect:

Rarely observed   dyspepsia , Watery eyes, nausea, dizziness. Long-term use of the drug is increased sleepiness, hypotension. The symptoms disappear spontaneously after discontinuation of the drug. If you are allergic to the components marked itching,   angioedema   and other allergic reactions. Overdose: drop in blood pressure, depression of the nervous system. It is necessary to stop taking the drug, treatment posimptomnoe.

Mode of application:

Korvalment capsule is placed under the tongue until complete dissolution hold. When the capsule crushing teeth effect is achieved quicker. Multiplicity of reception depends on the frequency and duration of angina attacks. In heart failure, it is recommended to take a sublingual capsule. The daily dosage may be up to 6 capsules in the treatment of angina in conjunction with other conditions. The course of treatment should not exceed a week with regular dosing.

Special instructions:

Korvalment not cropped attacks of severe angina. The drug is approved for use in patients with diabetes It does not contain sugar. When breastfeeding, pregnancy korvalmenta reception is allowed only in situations where the therapeutic effect is more important than the possible negative impact of the components of the drug on the fetus (baby). Experience with the drug in pediatrics there. In the early hours of the possible dizziness, drowsiness, so it is advisable to refrain from managing complex mechanisms driving transport activities requiring concentration, high concentration. Storage temperature 5-20 degrees Celsius.

Drug Interactions:

Korvalment can be used simultaneously with Riboxinum . asparkamom , Vitamin complexes and other drugs, improves metabolic processes in the body. Korvalment increases the effective action of antihypertensive drugs, opioid analgesics, psychotropic drugs, anesthetic drugs, alcohol. Integrated application with neyrotropami   It leads to the oppression of the nervous system, excessive sleepiness.