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 Farmatsitron
 Combined preparation struggling with symptoms colds   and ARI . It has analgesic, vasoconstrictor, antihistamine, analgesic effect. In its composition comprises: paracetamol   (acetaminophen) - has a major impact on the synthesis of prostaglandins   in the CNS, blocking pain impulses conduct reduces body temperature, has a bland anti-inflammatory effect. Acetaminophen comes through placenta , Completely absorbed from the GASTROINTESTINAL TRACT, is adjudged to be into breast milk. It is metabolized in the liver system. Operates for 4 hours. Excreted by the kidneys. Pheniramine maleate   - Histamine receptor blocker, prevents swelling of the tissues, reduces vascular permeability, reduces the severity of local reactions exudative, struggling with itching in the nose, the eyes, eliminates tearing. It has good absorption, it is biotransformed in the liver. F e nilefrin hydrochloride   It constricts blood vessels and stimulates alpha arenoretseptory, reduces swelling of sinuses, nasal mucosa, is a sympathomimetic. Action of phenylephrine lasts 20 minutes. It metabolised in the GASTROINTESTINAL TRACT, the liver. Metabolite excreted by the kidneys. Ascorbic acid   It restores the body's need for vitamin C in the "common cold" infections, increases the body's resistance to the action of microorganisms. It accumulates in the cells and blood plasma, the highest concentration observed in the glandular tissue. Available in the form of granular, free-flowing powder.


Indications:

Farmatsitron prescribed for viral, infectious respiratory diseases Which are accompanied by nasal congestion, headaches, muscle aches, fever. Farmatsitron effectively relieves pain to moderate severity: neuralgia I , toothache, myalgia . migraine . arthralgia , Tuberculosis. The drug is effective in acute rhinitis, sinusitis, allergic rhinitis.

Contraindications:

Farmatsitron not prescribed for chronic alcoholism, portal hypertension , Renal failure, pregnancy. Be wary of angle-closure glaucoma, hyperbilirubinemia   (Zhilberra syndrome, Rotor's, Dubin-Johnson syndrome), prostatic hyperplasia .
Farmatsitron not appoint persons under the age of 6 years.

Side effect:

Epigastric pain, increased blood pressure, mydriasis, disturbance of sleep, accommodation paresis, dizziness, allergies, increased intraocular pressure, thrombocytopenia,   dry mouth, agranulocytosis . anemia , Urinary retention. Chronic administration of high doses Farmatsitrona develop aplastic anemia, pancytopenia, carbohemia , Hemolytic anemia, pernicious showing signs of hepatotoxic effect of paracetamol, papillary necrosis .   interstitial nephritis . glycosuria .

Mode of application:

Powder sachets diluted in a beaker (200 ml) of hot water. Multiplicity of reception - 4 times a day, not more than 5 of day.

Overdose:

Due to the effect of paracetamol on the body: gepatonekroz , Dyspepsia, pale skin, loss of appetite, increased levels of liver enzymes, increased rate of prothrombin time. Rarely develops tubular necrosis , Wears lightning-fast the character of. Recommended administration methionine And after 12 hours - N-acetylcysteine . The further tactics of determined by the state the patient's, level of paracetamol in the blood.

Special instructions:

Patients with diabetes need to take into account that 1 bag contains 20 grams of sugar. Not compatible with ethanol. Reduces the rate of reaction.

Drug Interactions:

Farmatsitron potentiates the effect of ethanol, MAO inhibitors, sedative drugs, indirect anticoagulants. At simultaneous reception antipsiholitikov, antidepressants, fetiazina derivatives, antiparkinsonian drugs increases the risk of constipation , Delays of urine, dryness in the mouth. In conjunction with glucocorticosteroids   rises the intraocular pressure. Farmatsitron reduces the effect of uricosuric drugs. Tricyclic antidepressants increase its sympathomimetic effect. In combination with with halothane probably development of ventricular arrhythmia. Farmatsitron reduces the ability of guanetidina   have hypotensive effect, but enhances the effect of adrenostimuliruyuee of phenylephrine .