Description overdue on 06.11.2011

It has antipyretic, analgesic and antihistamine effect. In its composition contains paracetamol , Phenylpropanolamine, caffeine   and chlorphenamine. The therapeutic effect is achieved through the interaction of the components Flyukolda. Paracetamol inhibits cyclooxygenase, which leads to reduced production prostaglaninov , Arachidonic acid, thromboxane   and prostacyclin . It is a non-narcotic analgesic . It has a slight anti-inflammatory effect, but a pronounced anti-pyretic and analgesic effect. Lowers prostaglandins   in the CNS, thermoregulatory center of the hypothalamus. Phenylpropanolamine   and chlorpheniramine   eliminate the swelling of the nasal mucosa, fight rhinorrhea   and facilitate breathing through the nose. Chlorpheniramine blocks histamine H1-receptors, has m-anticholinergic and sedative effect. Caffeine is neuroleptic It enhances the therapeutic effects of NSAIDs, improves memory, attention, improves performance, stimulates the central nervous system. Flyukold absorbed in the digestive tract, metabolites are excreted in urine. The components of the drug through the blood-tested and blood-brain barriers, get into breast milk.

Indications:

Flyukold relieves symptoms of colds, acute respiratory disease: rhinorrhea, nasal swelling, headaches, fever, myalgia, and others.

Contraindications:

Flyukold not prescribed to patients with hypertension, renal failure, heart failure, liver failure, coronary heart disease, pregnancy, pediatrics (under 6 years). Allergies.

Side effect:

Flyukold well tolerated. Side effects are rare. Gastrointestinal tract : Dyspepsia, epigastric pain, dry mouth , Violations of the chair. FROM erdechno-vascular system : Increased blood pressure, thrombocytopenia, leukopenia, heart rhythm disturbances, neutropenia, carbohemia . Central nervous system : tremor of the extremities . migraine , Irritability, insomnia, emotional lability, dizziness. Allergies.

Mode of application:

Flyukola tablet not chewed, swallowed whole, washed down with water. The drug is taken three times a day 1 tablet. Between doses should be at least 4 hours. At 5 hours no more tablets are not longer than a week.

Overdose:

Epigastric pain, dyspepsia, tremor   limbs, tachycardia Sleep disorders. Notes nephrotoxic and hepatotoxic effects of high doses of paracetamol. 10 grams of paracetamol cause encephalopathy with risk of death. In addition to the adsorbents introduced methionine . N-acetylcysteine .

Special instructions:

If the reception Flyukolda temperature drops more than 3 days, and the pain does not subside over 5 days, it is recommended to consult a doctor. To use caution in patients with diabetes. The drug reduces the rate of reaction.

Drug Interactions:

Ascorbic acid, codeine, propyphenazone, scopolamine enhance the therapeutic effect of the drug Flyukold. Ethanol, sedative drugs, tricyclic antidepressants, barbiturates   increase the half-life of the drug. Not recommended combined with drugs in the composition containing paracetamol.