Description overdue on 09/28/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Kondilina (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Synonyms
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

1 ml of solution for external application comprising:

• 5 mg Podophyllotoxins   - Active substance.

Auxiliary ingredients:

• 735 mg - ethanol ;
• 7, 79 mg - sodium lactate;
• 51 67 mg -   lactic acid;
• 30, 6 mg - purified water.

Product form

A solution to further external application.

Packing solution contains one vial complete with applicator.

Pharmacological action

Mestnonekrotiziruyuschee.

Pharmacodynamics and pharmacokinetics

Podophyllotoxin , Which is the active ingredient of the drug Kondilin most active ingredient podofillina Which is obtained from plant extracts. The medicament comprises standardized Podofillotoksi n   deep cleaning, about 99%.

The drug has a cytostatic effect. When applied topically exhibits mummified and cauterizing action It leads to necrosis of the outer warts.

Within 30-60 minutes after applying the 0, 01-0, 0 05 mL, 5% solution Podophyllotoxins   observed its low concentration in the blood serum.

When applications 0, 1 ml Kondilina (warts more than 4 cm2) content in serum Podophyllotoxins 60-120 minutes is 5 ng / ml, and decreased in 4 hours after the application of up to 3 ng / ml.

When using 0, 15 ml of pharmacokinetic parameters of the active substance, in contrast to previous doses show slower elimination of the drug (less than 1 ng / ml 12 hours after application).

T1 / 2 ranges from 60 minutes to 4 and 5 hours.

No cases of cumulation Podophyllotoxins   not observed.

Indications

Kondilin medicament is intended for topical use in genital warts.

Contraindications

• Hypersensitivity to Podophyllotoxins   or other ingredients of the drug Kondilin;
• concomitant use of other drugs, which include Podophyllotoxin;
• period pregnancy   and breast-feeding ;
• patient age of 12 years.

Side effects

There may be allergic reactions .

When treating Warts   large sizes preputial area Occasionally observed the development of balanoposthitis and edema.

Among the reactions of local character were identified: pain   (often ill-defined) redness   the site of application solution, ulceration of the epithelial layer warts   (usually occur early in the course of therapy for 2-3 hours of the drug).

Instructions for use Kondilina (method and dosage)

For application of the drug to Kondilin warts , You must use the supplied plastic applicator. The tip of the applicator in the form of loops recommend moisten solution so that its opening is completely filled, then produce the selected applique warts . The procedure is repeated, dampening solution preparation each remaining warts But not more than 50 times.

Instructions on Kondilin recommends a 3-day course of treatment with applications 2 times a day. After a course of treatment is necessary to take a break (at least 4 days). Further the possibility of repeated 3-day courses of therapy, but with a total duration of no more than 5 weeks.

The solution of the drug to be discharged solely on warts,   as its effects on healthy mucous membranes and skin areas can be the cause of a strong irritation and / or ulceration.

After the procedure, applications Kondilinom, place of use of the solution must be thoroughly dry in order to avoid possible irritation of healthy skin in contact with the treated acuminata.

Overdose

Keep in mind that when applied externally Kondilina in high doses it must be thoroughly washed off with soap.

In case of accidental oral (inner) taking the drug Kondilin to assign gastric lavage as well as to monitor the gas and electrolyte balance, monitor liver function and pattern of peripheral blood.

Cooperation

Avoid concurrent use Kondilina and other drugs in the same affected area.

The appointment of other drugs containing Podophyllotoxin with Kondilinom, it may increase its plasma concentration and consequently an increased risk of adverse side effects.

Terms of sale

Prescription.

Storage conditions

The temperature is not above 25 ° C.

Shelf life

4 years.

Cautions

Kondilin use the drug must be with caution.

Case of contact with the mucous membrane of eyes, wash immediately with plenty of water, because of the possible expressions of eye irritation.

Apply Kondilin to be pre-washed with soap and water and well dried the affected areas of the body.

When applying the drug should be to minimize its penetration to healthy skin and mucous membranes that surround warts . In particular, when used for the treatment solution warts,   localized in the area of ​​the labia minora and prepuce.

Local reactions (ulceration, irritation)   body areas adjacent to warts It can be prevented by applying them to preliminary zinc ointment, neutral creams, protective ointments, petroleum jelly.

With the development of balanoposthitis and / or edema   possible appointment of anti-inflammatory drugs (such as local glucocorticoids ).

Application Kondilina body surface larger than 10 cm2 can cause reactions associated with the resorptive effect of the active substance.

Recommend a survey and, if necessary, the appointment of the treatment of sex partners. During the period of treatment should refrain from sexual intercourse or use barrier contraceptives.

Analogs Kondilina

Analogs drug Kondilin presented subgroup of drugs with a similar action:

• Atsgerpin;
• Acyclovir;
• Bonafton;
• Viroleks;
• Gerpferon;
• Zovirax;
• Epigenes;
• Imiquimod   etc.

Synonyms

Synonyms drug Kondilin with the same active ingredient Podophyllotoxin: Kondilayn Nycomed (or Kondilin Nycomed) and Vartek GlaxoSmithKline.

Babies

The drug Kondilin not assigned to patients who have not reached the age of 12 years.

During pregnancy (and lactation)

Kondilin drug is contraindicated for use during the period pregnancy   and breast-feeding .

Reviews Kondiline

Reviews Kondiline talk about high efficiency of the drug and the complete disappearance of the external manifestations of the disease (warts) . At the same time there were some painful process, especially when hit on the solution not previously protected areas of the body.

Price Kondilina where to buy

Price Kondilina, depending on the region of Russia, vary from 500 to 800 rubles.

Buy this medicine in Moscow, you can, on average, for 600 rubles.