Description overdue on 08/09/2014
- Latin name: Acnecutan
- ATC code: D10VA01
- Active substance: Isotretinoin (Isotretinoin)
- Manufacturer: SMB TECHNOLOGY, S.A. (Belgium)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Side effects
- Instructions for use Aknekutana (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One capsule size №3 or 1 respectively contained 8 or 16 mg. a highly active compound isotretinoin.
In addition, the drug composition includes excipients such as refined soybean oil, complexes substances Gellyutsir 50/13 ( ), As well as Span0 ( and sorbitol esters of oleic acid ).
The capsule shell contains titanium dioxide, gelatin, red iron oxide, and indigo carmine (10 mg.).
Product form
Hard gelatin capsules brown №3 (8 mg.) Or №1 (10 mg.). The contents of the capsules is a waxy paste different orange-yellow tinge. The carton can be 1, 2, 4, and 7 to 14 blisters or capsules, 2, 3, 5, 6, 9 blisters 10 or 14 capsules.
Pharmacological action
The medicament has antiinflammatory and antiseborrhoeic abilities, and provides regenerating effects on skin .
Pharmacodynamics and pharmacokinetics
Through the presence of the drug in the composition isotretinoin Aknekutan improves the clinical picture in severe forms acne Which do not lend themselves to other types of therapeutic treatment. sebaceous glands .
Since sebum - Is the best environment for the development of malware bacteria Propionibacterium acnes, which cause the formation of acne , Downsizing sebaceous glands and decrease in their activity slows down bacterial colonization of the duct.
Aknekutan influences acne Inhibiting the proliferation of sebocytes, thus restoring process Cell Differentiation, thus stimulating regeneration. Isotretinoin, contained in the composition of the drug, has a inflammatory effects on skin.
Indications
The main contraindications of the drug are:
- period Lactation ;
- pregnancy ;
- hepatic impairment;
- hyperlipidemia;
- hypersensitivity;
- hypervitaminosis A.
Aknekutan not recommended for use in the treatment of children under the age of 12. diabetes, alcoholism As well as violations , Obesity and depression .
Side effects
When using the drug may experience symptoms hypervitaminosis A , T. E. May appear xerosis . conjunctivitis . bleeding from the nasal cavity . hoarseness . intolerance to contact lenses . Aknekutan can cause such as: peeling skin, Sweating . paronychia . itch and rash . dermatitis . onihodistrofiya . photosensitization , and exacerbation of acne .
- Digestive System , eg, diarrhea, bleeding, gum disease, pancreatitis;
- CNS - nausea, headache, blurred vision, seizures, convulsions;
- senses - photophobia, xerophthalmia, keratitis, optic neuritis, impaired hearing;
- Respiratory System and expressed in bronchospasm
- circulatory system as neutropenia, anemia, leukopenia, decrease in hematocrit.
Instructions for use Aknekutana (method and dosage)
Capsules with the active drug compound is best taken with food no more than 2 times a day. Aknekutana Dosage depends on the severity of the disease and the patient's health. The recommended initial dose of 0, 4 mg. per kilogram of body weight per day.
In severe forms acne the dosage may be increased to a maximum of 2 mg. per kilogram of body weight per day. Full remission patients observed approximately 24 hours of use of the drug. Particular attention to the dosage of the drug should be paid to patients with renal failure .
Overdose
In overdose symptoms of hypervitaminosis Aknekutanom Group A. In order to eliminate the negative consequences of non-compliance with the recommended dosage of the drug should be gastric lavage, and stop using the medication.
Cooperation
Efficiency can lower Aknekutana antibiotics Belonging to tetracycline series . To avoid burns should not be taken in conjunction with the preparation of medicines, increasing photosensitivity . The risk of developing gipervitaminoza type A increases retinoids Which is also not recommended for use in conjunction with this drug.
Isotretinoin Contained in a preparation can impair the effectiveness of means Contraception with a small amount progesterone . In order to avoid irritation develops Aknekutan not apply in conjunction with keratolytic agents.
Terms of sale
Storage conditions
The drug was stored at a temperature of 25 C, in a place protected from light.
Shelf life
2 years.
Cautions
Before the actual start of and during the therapeutic treatment Aknekutanom function should be monitored liver lipids, triglycerides, and hepatic enzymes.
At the time of treatment, patients are advised to avoid direct sunlight and do not ignore the moisturizer and use tools to help prevent dry skin and lips.
dermoabrazii .
The drug can affect your concentration, so you should be wary of driving a car while taking Aknekutana.
Analogs
Among similar drugs can be identified:
- ;
- Retasol;
- ;
- Retinoic ointment;
- Erase .
What better Aknekutan or Roaccutane
The chemical composition, shape and drug release effects of these drugs are similar to each other, and the difference Aknekutana Roaccutane It is only in the number of active compound contained in a capsule formulation. AT Roaccutane can contain up to 20 mg. isotretinoin So Aknekutan considered more gentle alternative and at the same time, effective treatment against acne.
Babies
Not used in the treatment of children under 12 years.
During pregnancy (and lactation)
Aknekutan forbidden to use during pregnancy and lactation.
Reviews Aknekutane
However, not all are unanimous on this preparation, as it has many side effects. In addition, some patients' feedback, talking about short-term effect of expensive drug, cast doubt on the real benefits of this drug.
Price Aknekutana where to buy
Price Aknekutana (capsules 16 mg., 30 pcs.) In some areas can reach 2500 rubles.
Buy a Moscow drug (capsules 8 mg. 30 pcs.) Can be the average for 1100-1200 rubles.