Description overdue on 08/09/2014

  • Latin name: Acnecutan
  • ATC code: D10VA01
  • Active substance: Isotretinoin (Isotretinoin)
  • Manufacturer: SMB TECHNOLOGY, S.A. (Belgium)
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications
  • Side effects
  • Instructions for use Aknekutana (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Cautions
  • Analogs
  • Babies
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

Composition

One capsule size №3 or 1 respectively contained 8 or 16 mg. a highly active compound   isotretinoin.

In addition, the drug composition includes excipients such as refined soybean oil, complexes substances Gellyutsir 50/13 ( ), As well as Span0 ( and sorbitol esters of oleic acid ).

The capsule shell contains titanium dioxide, gelatin, red iron oxide,   and indigo carmine   (10 mg.).

Product form

Hard gelatin capsules brown №3 (8 mg.) Or №1 (10 mg.). The contents of the capsules is a waxy paste different orange-yellow tinge. The carton can be 1, 2, 4, and 7 to 14 blisters or capsules, 2, 3, 5, 6, 9 blisters 10 or 14 capsules.

Pharmacological action

The medicament has antiinflammatory and antiseborrhoeic abilities, and provides regenerating effects   on skin .

Pharmacodynamics and pharmacokinetics

Through the presence of the drug in the composition isotretinoin   Aknekutan improves the clinical picture in severe forms   acne Which do not lend themselves to other types of therapeutic treatment.   sebaceous glands .


Since   sebum - Is the best environment for the development of malware bacteria Propionibacterium acnes, which cause the formation of acne , Downsizing sebaceous glands   and decrease in their activity slows down bacterial colonization of the duct.

Aknekutan influences acne Inhibiting the proliferation of sebocytes, thus restoring process Cell Differentiation,   thus stimulating regeneration. Isotretinoin,   contained in the composition of the drug, has a inflammatory effects on   skin.

Indications

The main contraindications of the drug are:

  • period Lactation ;
  • pregnancy ;
  • hepatic impairment;
  • hyperlipidemia;
  • hypersensitivity;
  • hypervitaminosis A.

Aknekutan not recommended for use in the treatment of children under the age of 12. diabetes, alcoholism As well as violations , Obesity and depression .

Side effects

When using the drug may experience symptoms   hypervitaminosis A , T. E. May appear xerosis . conjunctivitis . bleeding from the nasal cavity .   hoarseness . intolerance to contact lenses . Aknekutan can cause such   as: peeling skin, Sweating . paronychia . itch   and rash . dermatitis .   onihodistrofiya . photosensitization , and exacerbation of acne .

  • Digestive System , eg, diarrhea, bleeding, gum disease, pancreatitis;
  • CNS -   nausea, headache, blurred vision, seizures, convulsions;
  • senses - photophobia, xerophthalmia, keratitis, optic neuritis, impaired hearing;
  • Respiratory System   and expressed in bronchospasm
  • circulatory system as neutropenia, anemia, leukopenia, decrease in hematocrit.

Instructions for use Aknekutana (method and dosage)

Capsules with the active drug compound is best taken with food no more than 2 times a day. Aknekutana Dosage depends on the severity of the disease and the patient's health. The recommended initial dose of 0, 4 mg. per kilogram of body weight per day.

In severe forms acne   the dosage may be increased to a maximum of 2 mg. per kilogram of body weight per day. Full   remission   patients observed approximately 24 hours of use of the drug. Particular attention to the dosage of the drug should be paid to patients with renal failure .

Overdose

In overdose symptoms of hypervitaminosis Aknekutanom Group A. In order to eliminate the negative consequences of non-compliance with the recommended dosage of the drug should be gastric lavage, and stop using the medication.

Cooperation

Efficiency can lower Aknekutana   antibiotics Belonging to tetracycline series . To avoid burns   should not be taken in conjunction with the preparation of medicines, increasing photosensitivity . The risk of developing   gipervitaminoza type A increases retinoids Which is also not recommended for use in conjunction with this drug.

Isotretinoin Contained in a preparation can impair the effectiveness of means Contraception   with a small amount progesterone . In order to avoid irritation develops Aknekutan not apply in conjunction with keratolytic agents.

Terms of sale

Storage conditions

The drug was stored at a temperature of 25 C, in a place protected from light.

Shelf life

2 years.

Cautions

Before the actual start of and during the therapeutic treatment Aknekutanom function should be monitored liver lipids, triglycerides, and hepatic enzymes.

At the time of treatment, patients are advised to avoid direct sunlight and do not ignore the moisturizer and use tools to help prevent dry skin and lips.

dermoabrazii .

The drug can affect your concentration, so you should be wary of driving a car while taking Aknekutana.

Analogs

Among similar drugs can be identified:

  • ;
  • Retasol;
  • ;
  • Retinoic ointment;
  • Erase .

What better Aknekutan or Roaccutane

The chemical composition, shape and drug release effects of these drugs are similar to each other, and the difference Aknekutana Roaccutane   It is only in the number of active compound contained in a capsule formulation. AT Roaccutane   can contain up to 20 mg. isotretinoin So Aknekutan considered more gentle alternative and at the same time, effective treatment against acne.

Babies

Not used in the treatment of children under 12 years.

During pregnancy (and lactation)

Aknekutan forbidden to use during pregnancy and lactation.

Reviews Aknekutane

However, not all are unanimous on this preparation, as it has many side effects. In addition, some patients' feedback, talking about short-term effect of expensive drug, cast doubt on the real benefits of this drug.

Price Aknekutana where to buy

Price Aknekutana (capsules 16 mg., 30 pcs.) In some areas can reach 2500 rubles.

Buy a Moscow drug (capsules 8 mg. 30 pcs.) Can be the average for 1100-1200 rubles.

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