Description overdue on 12/15/2014

  • Latin name: Diacarb
  • ATC code: S01EC01
  • Active substance: Acetazolamide (Acetazolamide)
  • Manufacturer: Polpharma (Poland)
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications Diamox
  • Contraindications
  • Side effects
  • Instructions for use Diamox (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Analogs
  • Diakarb children
  • Newborns
  • During pregnancy (and lactation)
  • Reviews
  • Price, where to buy

 Diakarb

Composition

The drug contains as active substances acetazolamide .

Additional ingredients: potato starch, sodium starch glycolate, talc.

Product form

Available in a round flat white tablets.

Pharmacological action

Diuretic   and decongestant   means.

Pharmacodynamics and pharmacokinetics

Tablets are Diakarb diuretic . Their diuretic effect associated with carbonic anhydrase inhibition Taking part in the exchange of carbon dioxide. Inhibition of this action enzyme   It occurs in renal tissue. As a result, it decreases the degree of re- Absorption   at blood   urine sodium ions and bicarbonate.

This drug also helps in cardiopulmonary diseases Which may appear in some lung diseases, for example, in emphysema . In addition it can be used in the excessive intracranial pressure. He inhibits carbonic anhydrase   brain, which leads to reduced formation of cerebrospinal fluid and intracranial pressure. Accordingly, cleaned and related symptoms, for example, headache .

Once in the body, the drug also inhibits carbonic anhydrase   ciliary body, which leads to its use in acute attacks Glaucoma . Its action causes a reduction in secretion of aqueous humor outflow and normalizes it.


In general, tablets are widely used in sodium and water retention in the body, as well as in the prevention edema   different genesis . Thus, they can be used in the treatment of many diseases. By helping to normalize the water-salt metabolism, they do not violate the acid-alkaline balance. The duration of action up to 12 hours.

After oral application of 500 mg maximum drug concentration in plasma is reached after 2 hours. Its action is characterized by a high degree of association with plasma proteins. The active substance penetrates placental barrier.

The drug eliminated via the kidneys in unchanged form, mainly during the day.

Indications Diamox

Only as   diuretic   Diakarb drug is rarely used, as there are more effective drugs of this series. But it is often used for diseases not related to the genitourinary system, if there are appropriate indications for use Diamox.

Not recommended on their own, without consulting a doctor to take these pills, from which they can help and how to act, know only a specialist.

Indications Diamox may include the following:

  • Edematous syndrome   (moderate or mild severity);
  • Epilepsy   (as a means of combined treatment);
  • Glaucoma ;
  • Mountain sickness ;
  • Some lung diseases, when accumulate a lot of carbon dioxide and bicarbonate in the blood.

Contraindications

Do not use the tool in case of hypersensitivity to its components, hepatic insufficiency . acidosis . Addison's disease . diabetes . breast-feeding . pregnancy . Acute renal failure . hypokalemia . gipokortitsizm . uremia .

With care it is prescribed for edema   the renal and hepatic origin and in the use of high doses of aspirin.

Side effects

Side effects while taking the drug may be as follows: hypokalemia . convulsions . paresthesia . anorexia . itch . hives . muscular weakness . hyperemia   skin sensation of tinnitus metabolic acidosis, myopia .

When long-term therapy may appear nephrolithiasis . glycosuria . leukopenia , Disorientation, drowsiness , Vomiting, allergy . hematuria . hemolytic anemia . agranulocytosis , Breach of touch, nausea, diarrhea .

If the reception of the funds were side effects, you should seek medical attention immediately.

Instructions for use Diamox (method and dosage)

Those who appointed Diakarb pills, instruction on the application reports that the dosage regimen may vary depending on the disease characteristics of the organism and the patient's age.

When edema syndrome   the initial daily dose is 250-375 mg. Accepted need to once a day. Maximum diuretic effect appears after 1-2 days of reception. Then, it is desirable to make a break for 24 hours. When you receive medication instructions for use Diamox recommends passing the therapy of circulatory failure, replenish potassium levels and comply with the restrictions on the consumption of salt diet.

With open-angle glaucoma take medicine several times a day. Dose - 250 mg. When Secondary glaucoma   appoint receiving 250 mg every 4 hours. Babies also administered 10-15 mg per 1 kg of body weight per day. The daily dose should be divided into several stages.

Tablets in dosage 500-1000 mg / day is recommended to be taken before climbing a mountain for 1-2 days. If symptoms mountain sickness   still appear, it is necessary to continue treatment for two days.

With epilepsy   adult patients yield 250-500 mg of drug per day. The course lasts for 3 days. Then you need to take a break. In turn, the instructions for use Diamox children includes the following daily dosage depending on the age:

  • 4-12 months - 50 mg;
  • 2-3 years - 50-125 mg;
  • 4-18 years - 125-500 mg.

When combined with anticonvulsant drugs initial daily dose is 250 mg. If required, it can be increased. But children should not take a daily dose greater than 750 mg.

In all indications, if the reception has been missed, the next dose should not be increased.

Overdose

In the case of the use of the drug in high doses probably increased side reactions. Treatment is symptomatic.

Cooperation

When combined with Diamox antiepileptic funds may increase osteomalacia . A cooperation with diuretics and Theophylline leads to considerable enhancement diuretic action. But this does not apply to acidifying diuretics . In this case diuretic effect, on the contrary, reduced.

The tool also increases the likelihood of toxic effects salicylates . Carbamazepine . non-depolarizing muscle relaxants , Drugs with digitalis, Ephedrine .

Terms of sale

For sale this drug only by prescription.

Storage conditions

Keep the medication you need in a dry place inaccessible to children at a temperature of 25 ° C. The tablets should be protected from exposure to sunlight.

Shelf life

Five years.

Analogs Diamox

Match code ATC 4th level:
  •  Diakarb
 Trusopt

Analogs Diamox is currently virtually absent. Some pharmacies can find a tool called Acetazolamide . In fact, it is another name for the same medication. Other analogs of the drug is not known.

Diakarb children

When Hydrocephalus   or hypertension-hydrocephalic syndrome   Diakarb often prescribed for children. It regulates the amount of cerebrospinal fluid. In addition, Diakarb children may appoint at glaucoma   or epilepsy .

Write out his prescription, as the use of this drug requires monitoring by a specialist. It is best to use it in the hospital, where monitoring of the child can be carried out at the appropriate level of quality.

However, to date there are cases when at a mild condition neurologist can prescribe the drug at home.

Parents should keep in mind that this tool can cause serious adverse reactions. It is necessary to monitor the status of the child, as they may appear cramps, nausea, muscular weakness . hypokalemia , Vomiting, allergic reactions. And with long-term treatment in children is sometimes a decrease in the number of leukocytes and hemolytic anemia . Often, if necessary long course can also assign Asparkam to reduce the output of potassium from the body.

Typically, the dosage the doctor selects himself after examining the child and the results of analyzes. According to the instructions Minimal dosage is 50 mg per day. The daily dose is given to a child receiving 1-2.

Diakarb for newborns

Babies under one year may be given the drug if epilepsy . In addition, for newborns Diakarb used in excessive increase or divergence of the skull sutures. It helps to reduce the amount of cerebrospinal fluid.

Infants, the tool is assigned a doctor. Admission Diamox requires careful monitoring specialist.

The best option - monitor the baby in the hospital throughout the course. However, this drug is often given in the home. In this case, the expert is obliged to warn parents about possible adverse reactions and to specify the exact timing of the reception (no more than 5 days). Upon completion of the course is necessary to once again pass the relevant tests.

During pregnancy (and lactation)

This tool can not be taken at pregnancy . If you need the drug during Lactation , Breast-feeding should be discontinued.

Reviews diakarb

Opinions about the drug can meet the most different. Some reviews of diakarb report that the medication helped, and in others - people complain of side effects. In the latter case, most often talk about the appearance of seizures, and muscle weakness . But on the whole, positive feedback about Diamox still occur frequently.

Some forums also wondered whether it is possible to use the tool in pregnancy. This question unambiguously experts give a negative answer. Pregnant women are not assigned to the drug.

Price Diamox where to buy

Tablets Diakarb rates are quite affordable. They can be found in many pharmacies. Price Diamox about 210 rubles. It sold the tool in Ukraine. Price Diamox tablets 250 mg (30 pieces per pack) is an average of 140 hryvnia.

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