Description overdue on 08.09.2012

Non-steroidal, anti-inflammatory drug . The main ingredient - Nimesulide . The drug has analgesic, anti-inflammatory, antipyretic and antiplatelet properties. Other similar drugs in this group differs selective inhibition of cyclooxygenase-2 inhibition of synthesis of prostaglandins in inflammatory foci. The drug is less likely to cause adverse reactions in mind less pronounced inhibitory effects on cyclooxygenase-1. Nimulid available in tablet dosage form, in the form of gel beads.

Indications:

Nimulid prescribed for ankylosing spondylitis (ankylosing spondylitis), and synovitis, bursitis, rheumatism, osteoarthritis When myalgia, neuralgia, pain in the spine, inflammatory lesions of the musculoskeletal system , Soft tissue inflammatory. The drug is prescribed for infectious and inflammatory diseases, followed by feverish syndrome . The drug is effective in relieving pain: after injury, while algodismenoree .

Contraindications:

Nimulid not prescribed for bleeding from the digestive tract, erosive and ulcerative lesions of the gastrointestinal tract , Nimesulide intolerance during pregnancy, when "aspirin" asthma When hepatic insufficiency system. The drug does not designate children and in breast-feeding. With diabetes   Type 2, heart failure and hypertension medicament is used with caution.

Side effect:

Nimulid may cause stomachalgia , Diarrhea, vomiting, nausea, heartburn Allergic reactions, dizziness, ulceration of the mucous walls of the digestive tract, fluid retention, anemia, elevation of liver enzymes, leukopenia , Agranulocytosis, prolongation of bleeding time. Nimulid gel can cause skin itching, irritation, rash, transient discoloration of the skin.

Mode of application:

Nimulid pills taken by mouth after eating. Each tablet contains 100 mg of active ingredient nimesulide. The granulate of one packet must be diluted in 100 ml of water, taken twice a day. It is unacceptable storage solution more than a day. Babies of drug administered in the form of suspensions. Nimulid gel is applied evenly to the affected area, without rubbing. Column gel length 3 centimeters recommended put or render not greater 4-x times per day. In depending on the total response of the patient, from the square the treated area define the frequency of of application and amount of gel. The day may be used not more than 1 gel tube (corresponds 5mg / kg).

Special instructions:

Do not use occlusive dressings after applying the gel. It is unacceptable applying to the damaged areas of the skin, mucous walls, to protect the conjunctiva. Long-term therapy requires a systematic control over the work of the renal system.

Drug Interactions:

Myelotoxic medication in most cases increase haematotoxicity NIMULID. Pharmacokinetic interaction is determined at the level of binding to plasma proteins - raises the level of concentration of drugs that compete for binding to plasma proteins.