Description overdue on 06/23/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use structum
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition structum

One capsule contains active substance struktum - Chondroitin sulfate   sodium   - 250 mg or 500 mg.

Excipients: talc.

The composition of the capsule shell: titanium dioxide, indigo carmine, gelatin.

Product form

The capsules of 250 mg are produced:

• 15 pieces in blister packs; 4 of the blister cardboard packaging;
• 10 pieces in blister packs; 3 of the blister cardboard packaging;
• 30 pieces in a polypropylene bottle; one such vial in a carton;
• 100 pieces in a polypropylene bottle; one bottle in a cardboard box.

Struktum 500 mg   produced 12 capsules in blister packs; 5 of blisters in a carton box.

Tablets as release form, in the manufacture of the drug is not used.

Pharmacological action

Regenerating .   hondrostimuliruyuschee, anti-inflammatory.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Chondroitin sulfate   - One of the main components of cartilage and bone, joints, it helps to preserve the integrity of the cartilage due to:

• enhancing anabolic action chondrocytes   (activation products proteoglycans );
• inhibition of harmful effects interleukin-1β   structural components of cartilage;
• inhibition of excessive cartilage degradation (by blocking elastase   in tissues, reducing the activity metalloprotease   and increasing the activity of the inhibitor metalloprotease ).

Chondroitin sulfate   It improves the balance of synovial environment due to increased production hyaluronic acid   - Thus maintaining proper viscosity and density of the synovial fluid. Chondroitin sulfate also inhibits the development of inflammatory reactions.

Pharmacokinetics

After taking the drug for more than 70 percent of it is absorbed in the digestive tract. The maximum plasma concentration occurs within 3-4 hours, in the synovial fluid - within 4-5 hours. The bioavailability is about 13%.

Indications

The drug is used in the complex therapy of degenerative diseases of the spine and joints ( intervertebral osteochondrosis . osteoarthritis ).

Contraindications

• age less than 15 years (efficacy studies were not conducted);
• reaction hypersensitivity   to the drug.

Side effects

• on the part of the digestive system: nausea . vomiting ;
• reaction hypersensitivity : hives . itch .

Instructions for use structum

Instructions for use Structum 500 mg   to take medication orally with water.

Adults and children from 15 years of a medicine administered in a dose of 1 gram per day, or 500 mg 2 times a day - it is two capsules, saying " pills "Wrongly. The optimal duration of therapy is the initial six months. The therapeutic effect of the drug remains at 3-5 months depending on the stage of the disease and its localization. If necessary the repeated courses of treatment.

Overdose

Symptoms of overdose: rarely - vomiting . nausea . diarrhea , With long-term administration of high doses may cause hemorrhagic lesions .

Treatment: symptomatic therapy.

Cooperation

If use of the drug at the same time indirect anticoagulants, fibrinolytics   and antiplatelet , The effect of recent increases.

Terms of sale

Sold by prescription in the Ukraine and in Russia without a prescription.

Storage conditions

Keep away from children. Store at temperatures up to 25 degrees.

Shelf life

Three years.

Cautions

The drug must be used with caution in patients with a tendency to bleed.

Analogs structum

The most common analogs structum: Artron Hondreks . Chondroxide . Hondrofleks . Teraflex . Alflutop . Price analogues are much lower price of the original.

Babies

Prohibited reception to persons under the age of fifteen.

During pregnancy and lactation

The drug is contraindicated during pregnancy   and lactation.

Reviews structum

Reviews structum not fundamentally different from other reviews about the preparations of identical composition. Forums containing reviews of patients structum say that drugs Chondroitin   It is most effective as part of a treatment involving the procedure increases blood flow and gymnastics. Reviews physicians indicate greater effectiveness of injectables before the release of other forms (tablets and capsules).

Which is better: arthritis or Struktum?

Based on the comparison of the formulation can be concluded that the effect of Arthritis   more complex, since it contains additional glucosamine protecting cartilage from various injuries. For the rest, it is worth remembering that the injections have greater bioavailability, and treatment of diseases of the joints should be multicomponent.

Price structum

Price struktum (60 capsules of 500 mg) in Russia ranges from 980 to 1370 rubles.

Price Struktum tablets in Ukraine on average 840 hryvnia, and even more variable depending on the region. So, buy the drug in Kharkov will cost from 513 to 940 hryvnia. Injections of similar composition and action, it is usually possible to buy below the price structum.