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Hepatoprotectors
. Active ingredient -
ursodeoxycholic acid
. The drug has cholelitolitic, choleretic, hypocholesterolemic, hypolipidemic and immunostimulatory effects. Scientific studies have shown that the active substance reduces the hepatotoxicity of bile salts, and has a strong protective effect on the liver cells.
Medicine Ursol lowers cholesterol by reducing its absorption in the intestinal lumen. The product is capable of destroying of cholesterol gallstones. The active substance stimulates the formation and discharge of bile, as well as removal of toxic acids through the lumen of the intestine. Ursodeoxycholic acid enhances the secretion of gastric and pancreatic juice, increases the activity of lipases has hypolipidemic effect. By reducing the number of eosinophils, suppression products interleukins , Reduce the antigen expression is achieved immunomodulatory effect . Ursol The drug comes in the form of gelatin capsules with pink cap. One capsule contains 250 mg of ursodeoxycholic acid. Available in packages of 10, 50 or 100 capsules. Buy Ursol can be a pharmacy by presenting the prescription. Price Ursol in Ukraine ranges from 180 to 250 hryvnia.
Indications:
When primary biliary cirrhosis genesis recommended prolonged treatment with the drug Ursol. Instructions for use contain the following indications: the dissolution of cholesterol stones, biliary cirrhosis. Prescribers to dissolve the stones only in an existing gallbladder.
Contraindications:
Ursol not prescribed for atrophy of gallbladder , Acute pancreatitis, severe kidney and liver disease, biliary tract obstruction, non-operation in the gallbladder. In the presence of cholesterol stones larger than 2 centimeters, ursodeoxycholic acid is contraindicated. The drug is not indicated for the diagnosis of rengenokontrastnyh stones. Ursol contraindicated in liver cirrhosis (decompensated), during lactation, pregnancy, individual intolerance of ursodeoxycholic acid.
Side effect:
Treatment of biliary cirrhosis can lead to decompensated cirrhosis (docked after discontinuation of the drug). Changes in the digestive tract: diarrheal syndrome, nausea, vomiting, epigastric pain, increased ALT and AST, calcification of stones in the gall bladder, and constipation. Nervous system: dizziness, migraine. Perhaps the development of alopecia, psoriasis, myalgia, lung ailments, angioedema, and allergic reactions. Reviews on Ursol indicate good tolerability by following the doctor's recommendations.
Mode of application:
To dissolve stones: 2 capsules at night throughout the year. It is recommended to repeat the course after reaching the desired result for the prevention of re-formation of stones in the gallbladder. With biliary cirrhosis primary genesis administered 2 to 6 capsules per day (dosing depends on the weight of the patient). The calculation is made according to the scheme of 10-15 mg per 1 kg. Treatment reflux gastritis Biliary origin: 1 capsule 1 time at night. The course of treatment is calculated individually (maximum - 2 years).
Special instructions:
Analogs Ursoliva: Ursosan, Urso100, Ursofalk, Urdoksa. The drug can dissolve only stones containing cholesterol. It is important that the gallbladder was filled with not more than ½, the size of the stones does not exceed 20 mm, and the bile duct was active and passable. Mandatory control of enzymes ALT, AST, bilirubin. Recommended regular holetsistografii (every 3 months). Ultrasound should be done at least 6 months. After dissolution of cholesterol stones ursodeoxycholic acid treatment is carried out for 3 months to dissolve the debris, which can not be observed in ultrasound monitoring. If the size of the stones is not reduced within 6-12 months, the drug is cancel, and found to be ineffective therapy for a given patient. If you find nevizualiziruemaya gallbladder treatment ceased. Price Ursoliva 900 rubles.
Drug Interactions:
Estrogens, progestins, clofibrate, neomycin , Lipid-lowering drugs increase the saturation of bile with cholesterol, which can prevent the dissolution of stones in the gallbladder. Cholestyramine, antacids reduce the absorption of ursodeoxycholic acid. The medicament enhances the absorption of cyclosporine.