Description overdue on 12.12.2012

Tricyclic antidepressants . The main ingredient - pipofezine . The drug has sedative, timolepticheskoe effects. Description of the principle effects of Asaph: medication indiscriminately inhibits the process of reverse, neuronal uptake of serotonin and neurotransmitters norepinephrine Which leads to an increase in their concentration and subsequent relief of symptoms of depression. Pipofezine unlike other antidepressants have no effect on the activity of monoamine oxidase has no m-anticholinergic activity. For drug is not indicated cardiotoxic impact   on the human body. Azafen available in tablet dosage form.

Indications:

Drug Usage Azafen appoint him for depression (compared to alcohol abuse, when Exogenous depression , Endogenous depression, with anxiety and depressive states, astenodepressivnyh syndrome Depression in chronic somatic diseases occurring).

Contraindications:

Azafen not appoint diabetes, breastfeeding, liver disease and renal system, coronary heart disease, intolerance pipofezine basic substance, after suffering a stroke while taking monoamine oxidase inhibitors, when carrying a pregnancy. Babies Azafen used with caution.

Side effect:

Reviews indicate that the following side effects while taking the drug Azafen: vomiting, nausea, dizziness, headache Allergic reactions.

Mode of application:

The initial dose of the drug Azafen for adults is 25-50 mg twice daily in the morning and evening. The amount of drug may be increased background good tolerability of the treatment. The maximum daily dose is 400 mg pipofezine. The optimal dose is considered to be 0, 15-0, 2 grams. After achieving the desired therapeutic effect for the treatment of moving maintenance doses - 25-75 mg per day. Duration of treatment - up to 1 year.

Drug Interactions:

Azafen able to enhance the effect of antihistamines Ethanol, anticoagulants , Medicines, the effect of which depresses the central nervous system. The drug reduces the effectiveness of antiepileptic medicines .