Description overdue on 04/07/2014
- Latin name: Cereton
- ATC code: N07AX02
- Active substance: Alfostserat Choline (Choline Alfoscerate)
- Manufacturer: The Russian firm "Sotex"
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Cereton (spectrum use)
- Contraindications
- Side effects
- Instructions for use Cereton (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Reviews
- Price, where to buy
Composition
One ampoule (4 ml) containing 1 gram of the active ingredient alfostserata choline . Excipient - sterile water.
Every capsule It contains 400 mg of active substance. Additional components: iron oxide yellow, water, methylparaben . glycerol , titanium dioxide, propyl Sorbitol.
Product form
The drug is available in encapsulated form and a solution . Each pack of 14 capsules or 3, 5 vials of 4 ml.
Pharmacological action
Nootropics. The active substance provides delivery Choline cells of the brain. The current component is protected from enzymatic destruction. Choline is actively used in the process of synthesizing phosphatidylcholine and acetylcholine Normalizing the work of the affected receptors, increasing the elasticity of the membrane of neuronal cells, improving neuronal synaptic transmission.
With sufficient provision brain choline enhanced cerebral blood flow Activated reticular formation Stimulated cell metabolism . After a course of treatment is recorded regression severe neurological symptoms, marked improvement of blood circulation in the affected areas of the brain, improving cognitive performance. The drug has a positive effect on the brain activity of spontaneous genesis.
Pharmacodynamics and pharmacokinetics
For parenteral administration in a dose of 10 mg / kg of the active ingredient accumulates in the tissues of the lungs, brain and liver. Indicator Absorption - 88%. Active substance easily passes through blood-brain barrier . 15% of the metabolites derived through the intestine and through the kidneys; 85% of lung tissue is excreted as carbon dioxide.
Indications Cereton (spectrum use)
- senile psevdomelanholiya ;
- cognitive impairment;
- impaired attention;
- Dementia of unknown origin;
- encephalopathy unspecified origin;
- cerebral heart attack ;
- apathy ;
- after CVA ;
- encephalopathy ;
- organic mental disorders;
- behavioral disorders of organic origin (CNS dysfunction);
- senile dementia;
- lack of initiative, lack of motivation;
- loss of coordination;
- after intracranial hemorrhage;
- after brain injury.
Additional indications for use Cereton in the elderly: psycho-organic syndrome . cerebrovascular insufficiency . multinfarktnaya dementia .
Contraindications
The drug is not prescribed in the acute phase of stroke and hemorrhage. Pills and injections are contraindicated during gestation pregnancy , You are hypersensitive to choline and auxiliary components, Lactation . The drug is not used in pediatric (age limit - 18 years).
Side effects
Skin:
- hives ;
- rash.
The digestive tract:
- ulcerative lesions of the stomach;
- constipation ;
- gastritis ;
- pharyngitis ;
- dry mucous membranes of the mouth.
Nervous system:
- dizziness;
- hyperkinesia ;
- convulsions ;
- nervousness;
- anxiety;
- aggression;
- drowsiness;
- migraine ;
- ischemic changes in brain tissue.
Rarely recorded violation of urination, diarrheal syndrome Pain at the injection site.
Instructions for use Cereton (method and dosage)
The ampules administered mostly in acute conditions. The solution is administered intramuscularly or intravenously. Parenteral medication should be administered slowly. The daily dose - 4 mL (1 vial). The duration of treatment - 10-15 days. After the acute recovery period prescribed in the capsule.
Instructions for use in tablets Cereton
On the morning of 2 pieces, 1 piece at night. Duration of treatment - up to 6 months. With cerebrovascular disease chronic genesis At dementia 1 capsule three times a day in the course of 3-6 months. Preferably, the reception - after a meal.
Overdose
Large doses increase the severity of side effects. Posindromnaya requires adequate therapy.
Cooperation
Pharmacodynamics and pharmacokinetics of drug does not depend on the use of other drugs. Adsorbents Cereton may reduce the efficiency of the adsorption of the active substance.
Terms of sale
Leave upon presentation of a medical prescription form.
Storage conditions
Room temperature.
Shelf life
Ampoules - 2 years, capsules - 5 years.
Cautions
To prevent insomnia and overstimulation is not recommended medication in the morning.
Analogs Cereton (substitutes)
Cerepro
Gliatilin
Match pharmacological effects: Mexidol . Aktovegin .
Structural analogues Cereton: Gliatilin . Cerepro .
Reviews Cereton (Overview)
Portals and forums provide positive feedback on Cereton: the drug is well tolerated and has a strong nootropic effects .
Doctors about Cereton: drug improves cognitive function, helps to restore brain function after a stroke, traumatic lesions.
Price Cereton where to buy
Price solution: 3 vials - 300 rubles, 5 ampoules - 440 rubles.
Cost Cereton tablets: 800 rubles (28 pieces). In different regions Cereton price varies depending on the pharmacy network.