Description overdue on 05.02.2012

It reduces the intake of calcium into the cell, reduces the level of calcium in the depot plasmolemma reinforces vasodilatory effect of carbon dioxide, reduces the tone of smooth muscle of the arterioles. Cinnarizine has vasodilator effect It has no effect on blood pressure. Antihistamine Activity   the drug is moderate, lowers the tone of the sympathetic nervous system, moderately reduces the excitability of the vestibular apparatus. Cinnarizine is effective in patients with latent embodiment failure cerebral circulation At an initial form of atherosclerosis of cerebral vessels, after stroke . In patients with peripheral circulatory disorders improves the nutrition of tissues, organs, infarction, improves post-ischemic vascular lumen extension. Cinnarizine index decreases blood viscosity, moderately increases erythrocyte deformability, positively affects the elasticity of the membranes. Cinnarizine is available in capsule form, in tablet form.

Indications:

Cinnarizine prescribed after ischemic stroke , After suffering brain injuries, vascular encephalopathy, Meniere's disease , Vestibular disorders, for the prevention kinetoses. The drug is effective in Raynaud's disease, thromboangigitis obliterans , Senile dementia, migraine, sea and air sickness, obliterating atherosclerosis . thrombophlebitis , Angiopathy, paresthesia, trophic disorders.

Contraindications:

Cinnarizine is contraindicated during lactation during gestation pregnancy. In Parkinson's disease administered with caution.

Side effect:

Nervous system:   fatigue, drowsiness, extrapyramidal disorder , Depression, hyperkinesia, tremor of the extremities, headaches. Digestive system: cholestatic jaundice , Dyspepsia undergoing epigastric pain, dry mouth. Rarely observed sweating, allergies, drop in blood pressure, Lichen planus Obesity.

Overdose:

Drowsiness, vomiting, coma, excessive drop in blood pressure, tremor. Recommended intake adsorbents posimptomnaya therapy. Antidote is not developed.

Mode of application:

Cinnarizine is taken orally. In violation of the blood supply to the brain: three times a day by 25-50 mg. In violation of the peripheral circulation: three times a day by 50-75 mg. Prevention of sea and air sickness: 30 minutes prior to the event taking 25 milligrams. Labyrinth disorders: three times a day to 25 milligrams. Children dose is reduced by half. The effect is achieved by continuous treatment.

Special instructions:

Cinnarizine may cause false positive doping control in athletes. This effect is attributed to the action of antihistamine drug. Long-term use requires control over the work of the liver, kidneys, blood condition. Permissible to take the drug while breastfeeding. It affects transportation management.

Drug Interactions:

Cinnarizine enhances the action nootropics Sedatives, vasodilators, antihypertensives, ethanol. Reduces the effectiveness of hypertensive agents .