Description overdue on 01/08/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Neurox
• Contraindications
• Side effects
• Neurox, instructions for use
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• With alcohol
• Reviews
• Price, where to buy

Composition

In the 1 ml solution for intravenous or intramuscular injection contains 50 mg of active substance ( emoxypine ) And adjuvants: sodium bisulfite   - 1 mg; Water for injection - up to 1 ml.

Product form

• 1 ampoule (2 ml) at 5, 10, 20 and 50 pieces in a carton;
• 1 vial (5 ml) at 5, 10 and 20 pieces per carton.

Pharmacological action

• drug protects membranes of brain cells (neurons)   from any actions (membranoprotektivnoe action);
• It improves blood circulation in the brain neurons and reduces the need for oxygen (antihypoxic effect);
• It has a direct activating effect on mental activity (nootropic effect);
• removes anxiety . fear and voltage ;
• increases stress (anxiolytic effect);
• inhibits the development of seizures   (anticonvulsant activity).

Pharmacodynamics and pharmacokinetics

Active ingredient Neurox emoxypine (EMHPS)   It inhibits the toxic effects of free radicals produced during metabolism in the body and destroys cells and tissues. It protects the membrane (shell) of brain cells from any impact, improves their structure and function (including oxygen transport and neurotransmitters   - Substances with which information is transmitted in brain cells).

Under the action Neurox increases the concentration in the brain Dopamine Which is called the hormone of pleasure. All this leads to an increase in stress and mental abilities, reduce anxiety   and convulsive . Neurox has anti-toxic effects in acute and chronic alcohol intoxication At withdrawal syndrome   ( intoxication , Against the background of growing detachment from alcohol in patients chronic alcoholism ) And overdose agents affecting the central nervous system.

The duration of Neurox intramuscular injection - up to 4 hours. The maximum plasma concentration occurs within about 20 - 40 minutes after administration. The active ingredient is quickly transferred from the blood vessels in organs and tissues, and also is rapidly excreted in the urine, preliminary metabolizing   (decomposing into products of metabolism - metabolites ) In liver.

Indications Neurox

Indications Neurox:

• acute cerebrovascular accident, including ischemic stroke ;
• diseases associated with metabolic disturbances in brain cells ( entsefalopii );
• condition after suffering traumatic brain injury ;
• mild mental disorders on the background atherosclerosis ;
• anxiety in the background neuroses   and mental illness ;
• myocardial infarction   (as part of an integrated treatment).

Indications Neurox also include alcohol intoxication , Withdrawal syndrome with chronic alcoholism, acute intoxication by antipsychotic drugs ( neuroleptics ).

Medicine Neurox - contraindications for use

Neurox can not be used with the following diseases and conditions:

• severe disease, with acute renal impairment or hepatic ( acute renal   and hepatic insufficiency );
• pregnancy   and breast-feeding;
• hypersensitivity to the drug;
• children of all ages.

With care apply at Neurox allergic diseases   and reactions that have been patient in the past. During treatment should use caution when driving or performing other activities that require high concentration and speed of responses.

The drug Neurox - side effects

With the rapid administration (particularly when administered intravenously) may cause dryness and metallic taste in the mouth, tidal heat, sore throat and feeling short of breath. It is also possible allergic reactions .

If you use the drug rates in excess of the recommended duration, we can not rule out the emergence of nausea . increased gas in the intestines   and intestinal colic . sleepiness   or sleep disorders.

Neurox, instructions for use

Neurox administered intramuscularly or intravenously (bolus or infusion). When drip drug divorces saline (0, 9% NaCl). Dosages Neurox often selected individual physician in view of the disease state of the patient and the manufacturer's recommendations.

Instructions for use Neurox recommends starting treatment with a daily dose of 50-300 mg. The dose of 50 mg a better allocation of 2 - 3 introduction. Gradually increase the dose to produce a therapeutic effect. The maximum daily dose - 800 mg. The course of treatment depending on the patient and the dosage can vary from 5 to 30 days.

Drug is administered intravenously very slowly for at least 5 minutes, drip - with a speed of 40-60 drops per minute.

Injections Neurox - Is it possible overdose?

In overdose may occur insomnia   or, alternatively, sleepiness . If the drug is administered intravenously, it may be some rise blood pressure (BP)   for 90 - 120 minutes after administration. After this time, the symptoms of blood pressure comes back to normal on their own, being restored within days.

With insomnia   sometimes prescribed drugs from the group tranquilizers   (eg, Diazepam ) Minimal dosage.

Neurox Interaction with other drugs

Neurox potentiates (increases) action benzodiazepine tranquilizers   (eg, Diazepam ) antiepileptic   ( Carbamazepine ) antiparkinsonian   ( Levodopa ) And Medicine Nitrate   ( Nitroglycerine ). It reduces the toxic effects of alcohol.

Terms of sale

The pharmacy Neurox available only by prescription.

Storage conditions

The vials Neurox should be stored out of the reach of children, dry, dark place at a temperature no higher than 25 ° C.

Shelf life

The drug is stored for 3 years, subject to the above conditions.

Analogs Neurox

Analogs - a variety of dosage formulations groups which are used to treat the same disease. Analogs Neurox:

• agents from the group nootropics   ( Pyracetam . Phenibut );
• agents from the group benzodiazepine tranquilizers   ( Nozepam . Sibazon );
• agents from the group antiepileptics   ( Carbamazepine );
• preparations improving cerebral circulation   ( Vinpocetine );
• agents from the group antioxidants   ( vitamin C   and E ).

Alcohol and Neurox

Neurox reduces the toxic effect of alcohol.

Reviews Neurox

Reviews Neurox different, about half of them are positive, half - negative. The positive responses observed in the main effect of combined treatment of different Neurological Disorders , Which included including Neurox.

Negative comments about Neurox related to the lack of therapeutic effect after the course of treatment. Obviously, in many ways the effectiveness of this drug is associated with the correctness of his appointment and selected dosage.

Price Neurox

Price Neurox in Moscow depends on the dosage of the drug in a vial and the number of vials in the package:

• 10 vials of 2 ml - from 306 to 378 rubles;
• 50 vials of 2 ml - from 1066 to 1274 rubles;
• 5 vials of 5 ml - 287 - 349 rubles.

Price Neurox injections will depend on the chosen doctor dose and duration of treatment. Price Neurox tablets can not be determined, since this drug is not released in tablets.