Description overdue on 01.06.2012

Alpha-blocker . The main component - proroksan . The drug has a hypotensive, antipruritic, antiabstinentnoe and sedative effects. Pirroksan lowers blood pressure, peripheral vascular resistance, reduces the tone of smooth muscle in the wall of blood vessels (especially precapillaries, arterioles), improves blood flow to the mucous membranes, skin, muscle tissue. The medicament regulates the tonus sympathoadrenal It suppresses excitability diencephalic structures. Pirroksan available in tablet form, as a solution.

Indications:

Pirroksan used in withdrawal syndrome   (alcohol, morphine) at hypertensive crisis , Meniere's syndrome, diencephalic Stroke sympathoadrenal form at allergic dermatoses , Anxiety, withdrawal syndrome, for the prevention of air and sea sickness.

Contraindications:

Pirroksan does not apply in case of intolerance proroksana, atherosclerosis, heart failure, stroke, severe coronary artery disease. Elderly proroksan used with caution.

Side effect:

Angina pectoris , Bradycardia, drop in blood pressure, allergic response.

Overdose:

Manifested Orthostatic hypotension , A sharp drop in blood pressure, bradycardia . Timely maintenance of functioning of vital organs, the introduction koronarolitikov, ephedrine , Phenylephrine.

Mode of application:

Pirroksan administered subcutaneously, intramuscularly, taken orally. Relief of hypertensive crisis, diencephalic crisis: intramuscularly or subcutaneously administered at 20-30 mg proroksana (1% solution 2-3 ml). Prevention of hypertensive crises, inside 2-3 times a day for 15-30 mg. Prevention of motion sickness syndrome: a 30-minute trip to take 15 mg. Morphine abstinence: a course of 5 days, three times a day for 45 mg. Alcohol withdrawal: three times a day, intramuscularly or subcutaneously administered 30 mg, which corresponds to 3 ml of a 1% solution. Pruritic dermatoses, marked insomnia: bedtime inside proroksana 15-30 mg.

Special instructions:

The drug pirroksan required control parameters in blood sugar. Rarely recorded increase endogenous insulin .

Drug Interactions:

Antipsychotics , Butyrophenone, thioxanthene, phenothiazines, difenilbutilpiperidin reinforce the impact proroksana. CRM Index is reduced while the application procainamide.