Description overdue on 06/19/2014
- Latin name: Eglonil
- ATC code: N05AL01
- Active substance: Sulpiride (Sulpiride)
- Manufacturer: Sanofi Winthrop Industrie, France
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications eglonil
- Contraindications
- Side effects
- Instructions on Eglonil (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- With alcohol
- Reviews
- Price, where to buy
Composition
One tablet contains over 0, 2 0 g or 05 g of active ingredient sulpiride and additional substances ( potato starch, methylcellulose, talc, lactose monohydrate, silica, magnesium stearate ).
The solution for intramuscular injection (1 ampoule) sulpiride contains 0, r + 1 sodium chloride, water and sulfuric acid .
The solution for internal application 100 ml sulpiride 0, 5 g + auxiliaries.
Product form
The drug release in the form of gelatin capsules , The solid, yellow-gray tint, in the white-yellow powder. The packages of 15 or 30 capsules.
As a tan tablets , Scored on one side and the inscription "SLP200" with other packages of 12, 60 pieces.
In the form of colorless Injection Solution Odorless ampoules. Packages of 6 vials.
Pharmacological action
Neuroleptics.
Pharmacodynamics and pharmacokinetics
The drug has a rather moderate neuroleptic effect. The active substance selectively blocks dopamine receptors , While not exerting strong sedation . As low as medicine acts as a Antidepressant and stimulator .
Depending on the dose may eliminate delirium and hallucinations or simply tone up and reduce anhedonia . In very large doses, there is sedative effect.
Half an hour later (intramuscular) or 5 hours (oral) drug action occurs. The conclusion made by the kidneys, is not metabolized, the half-life of about 7 hours.
Indications eglonil
- abulia ;
- confusion and delirium ;
- agrammatism ;
- lethargy and other psychoses ;
- neuroses ;
- creeping schizophrenia ;
- psychosomatic disease .
It is also an indication for use is eglonil gastric ulcer and duodenal .
Contraindications
Pheochromocytoma . allergy into components.
Side effects eglonil
Side effects occur infrequently, in compliance with the dosage.
FEATURES:
- drowsiness and lethargy ;
- amenorrhea ;
- gynecomastia ;
- various kinds dyskinesias ;
- galactorrhea ;
- frigidity and impotence ;
- hyperthermia ;
- hyperprolactinemia ;
- orthostatic hypotension ;
- the occurrence of excessive weight.
Instructions on Eglonil (method and dosage)
Dosage, route of administration and duration should appoint an expert.
When using tablets daily dosage may be about 0, 2 - 1 gram capsules - 0, 05-0, 15 g dose divided into 3 doses, the rate - about a month.
To achieve the effect of rapid relief of acute symptoms or prescribe injections of the drug intramuscularly .
According to the instructions for use Eglonil, when using the drug in ampoules daily dose of 0, 4 0, 8, the injection is carried out three times a day, for two weeks, then transferred to a tablet or capsule.
Drugs recommends crush no more than 4 hours before bedtime to avoid insomnia .
Overdose
It may be: dyskinesia, spasms, torticollis, visual disturbances, hypertension, nausea, and dryness of the mouth, sweating and weakness, extrapyramidal effects .
Hemodialysis It gives partial relief. Therapy - according to symptoms closely monitor breathing and heart rhythm . Possible to use centrally acting anticholinergics .
Cooperation
Contraindications simultaneous reception cabergoline kinagolida, levodopa and Eglonil .
It is not necessary to combine with other sedatives and means ethanol Avoid mutual enhancing effects.
Precautions combined with blood pressure-lowering drugs.
Medication side effects in which there is the risk of paroxysmal ventricular tachycardia Should not be combined with Eglonilom.
Not recommended simultaneous reception: pentamidine, lumefantrine, halofantrine, antifungal agents, amantadine, apomorphine, bromocriptine, entacapone, lisuride, pramipexole, selegiline, disopyramide, kinidinom, sotalol, ibutilide, dofetilide, cisapride, erythromycin, moxifloxacin, ethanol, methadone, haloperidol, chlorpromazine etc.
Terms of sale
By prescription.
Storage conditions
Dark, cool place, not above 30 degrees.
Shelf life
3 years.
Cautions
During the reception means to refrain from driving motor vehicles.
Take special care for the sick epilepsy and Parkinson's disease In the elderly.
Analogs eglonil
The closest are Restful and Sulpiride-ZN .
Other common counterparts: Sulpiride, Tiaprosan, Soleron, Betamax, Solian, Tiaprilan .
With alcohol
Alcohol and Eglonil combination is not recommended. Also, do not take drugs containing the percentage of alcohol in any quantity.
Reviews Eglonile
Reviews of doctors : Eglonil often prescribed for various degree schizophrenia, neurosis Even when depression . Thanks to a beneficial effect on the gastric mucosa, moderate sedation, justified the use in the treatment of stomach ulcers and duodenal . Social long-term medication, courses. The positive effect is seen almost immediately.
Testimonials about Eglonile : The forums are mostly good reviews. In general, the effectiveness of drugs is different for different people, all individually. However, often complain of side effects such as headaches, mastitis, the shift of the menstrual cycle in women, weight gain.
On Wikipedia, the formulation is called sulpiride .
Price eglonil (Where to buy)
Cost tablets 200 mg, 313 rubles per 12 pieces.
Purchase capsules 50 mg, 30 pieces costs about 202 rubles.
Cost drug ampules - 357 rubles for 6 pieces of 2 ml.