Description overdue on 08/10/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Pantogam asset (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

1 capsule containing 200 mg or 300 mg Hopantenic acid (D, L)   - Active substance.

Auxiliary ingredients respectively the weight content of the active substance:

• 1, 02 or 1 mg, 53 mg - magnesium stearate;
• 13, 98 or 20 mg, 97 mg -   microcrystalline cellulose.

Capsules:

• gelatin;
• titanium dioxide;
• methyl parahydroxybenzoate;
• sodium lauryl sulfate;
• glycerol;
• Propyl;
• purified water.

Product form

Pantogam active medicament is released in the form of capsules, 200 mg or 300 mg.

One package may contain 30, 50 or 60 capsules.

Pharmacological action

Nootropic.

Pharmacodynamics and pharmacokinetics

Pantogam asset, in its structure, comprising   gamma-aminobutyric acid (GABA) , A direct impact on GABA B receptor channel complex . The drug is a racemic mixture of equivalent shares Hopantenic acid in the R-form and its S-isomer, whereby improved transport and interaction with the drug GABA receptors.   The drug Pantogam asset shows a more pronounced anticonvulsant and nootropic effect than first-generation drugs containing Hopantenic acid.

Pantogam asset increases the resistance of the brain to lack of oxygen ( hypoxia ), As well as to the effects of toxic substances it activates anabolic processes in neurons of the brain It combines mild stimulant effect with a mild sedative effect. Shows light antiastenicheskuyu and anxiolytic activity. It reduces the excitability of the motor, improves physical and mental activity, regulates behavior.   It prevents abnormal increase cystic reflex   as well as violation the tone of the detrusor.

When taken orally, the active ingredient Pantogam asset is rapidly absorbed from the gastrointestinal tract.

It has the ability to penetrate through BBB.

Do not metabolized and within 48 hours is excreted unchanged by the kidneys - 70%, and the intestines - 30% adopted earlier dose.

Indications

• epilepsy (with parallel receiving anticonvulsants);
• cerebrovascular insufficiency due to atherosclerotic cerebrovascular abnormalities;
• cognitive impairment in neurological disorders   and caused organic lesions of the brain (including the effects of traumatic brain injury and neuroinfections);
• extrapyramidal hyperkinesis (Parkinson's disease, Huntington's chorea, myoclonus epilepsy, hepatolenticular degeneration and so on.), extrapyramidal syndrome therapy, which was caused by the use of antipsychotic drugs;
• reduction of physical and mental activity, psycho-emotional overload, in order to improve memory and concentration;
• schizophrenia   (used in the complex treatment);
• neurogenic voiding (enuresis, pollakiuria, imperative mochenederzhanie, urgency to urinate).

Contraindications

• hypersensitivity Hopantenic acid   capsules or other ingredients;
• severe or acute renal failure;
• period breastfeeding ;
• first trimester pregnancy ;
• patient age of 18 years (due to lack of clinical research on the effects of Pantogam active at an earlier age).

Side effects

In some cases, there is allergic reactions (rash on the skin, conjunctivitis, rhinitis) . In the case of manifestations of these symptoms recommended dose reduction or complete abolition of therapy.

Also notes the short passing symptoms: noise in the head, sleep disturbances or drowsiness.

Instructions for use Pantogam asset (method and dosage)

Pantogam active medicament is intended for oral administration (internal) administration. Typically, the drug is taken 15-20 minutes after ingestion, 2 or 3 times a day. Recommended time of reception in the morning or afternoon hours.

Normal dosage capsules in 200 mg of - 0, 2-0, 8 g (1-4 capsules) per day.

Capsules of 300 mg - 0, 3-0, 9 g (1-3 capsules) per day.

The maximum allowed daily dose Pantogam asset equals - 2, 4 g (12 capsules of 200 mg or 8 capsules of 300 mg).

The course of treatment lasts from 30 days to 4 months, in some cases, treatment is continued for 6-12 months. At the end of 3-6 months can be carried out a second course of therapy.

Overdose

If overdose Pantogam asset symptoms may increase its side effects.

Displaying   gastric lavage, enterosorbents, symptomatic therapy.

Cooperation

Pantogam asset enhances the action anticonvulsant drugs.

Potentiates the effects of drugs used to local anesthetic (Procaine).

In a joint application with barbiturates   prolong their action.

It prevents side effects Carbamazepine, phenobarbital, neuroleptics.

Combines reception Etidronic acid and glycine   Pantogam enhances the effect of the asset.

Terms of sale

Prescription.

Storage conditions

The temperature is not above 25 ° C.

Shelf life

36 months.

Cautions

In applying the drug Pantogam asset over a long period of time, concomitant use of other drugs with CNS stimulant and nootropic action , not recommended.

Analogs

• Vinpocetine;
• Glycine;
• Cavinton;
• Lutset;
• Nootropil;
• Piracetam;
• Fezam;
• Tiotsetam   etc.

Babies

It does not administered to patients under 18 years, due to the lack of clinical research on the effects of Pantogam asset in this age.

During pregnancy (and lactation)

Pantogam asset is contraindicated for use during pregnancy (I term), as well as during breastfeeding.

Reviews Pantogam asset

Reviews of patients in the active Pantogam neurotic disorders, epilepsy and schizophrenia (in the complex therapy), cognitive impairment due to brain injury, cerebrovascular insufficiency   talk about the high efficiency of the drug with minimal adverse events.

Excellent results showing its use in psycho-emotional overload, in order to improve mental performance and efficiency, as well as violations of urination   due to neurological diseases.

It should be remembered that the drug Pantogam asset designed to receive only adult patients and is contraindicated for children under 18 years. Especially for the treatment of children produced a synonym for drug Pantogam asset - Pantogam in syrup form.

Price Pantogam asset where to buy

Price Pantogam active drug in pharmacies Russia, on average - 400 rubles per 50 capsules.