Description overdue on 08/22/2014

  • Latin name: Proproten-100
  • ATC code: N07BB
  • Active substance: Brain-specific proteins Antibodies to the S-100
  • Manufacturer: OOO "NPF" Materia Medica Holding ", Russia
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  • Composition
  • Product form
  • Pharmacological action
  • Pharmacodynamics and pharmacokinetics
  • Indications for use of the drug
  • Contraindications
  • Cautions
  • Side effects
  • Proproten 100: instructions for use (method and dosage)
  • Overdose
  • Cooperation
  • Terms of sale
  • Storage conditions
  • Shelf life
  • Analogs
  • With alcohol
  • Reviews
  • Price, where to buy

 Proproten 100

Composition

100 g of the preparation in the form of droplets contained 1 g of active ingredient - brain-specific antibodies S-100 protein .

Each tablet contained purified   brain-specific antibodies to S-100 protein   - 3 mg. As well as excipients: lactose monohydrate . MCC and magnesium stearyl m.

Product form

The drug has two forms: pills Proproten 100 for sucking, packaged 20 pieces and packed 1, 2 and 5 blisters in a pack.

And drops   for intake of 25 ml dropper vial.

Pharmacological action

The drug has anti-hypoxic, and antiabstinentnym neuroprotective effect.

Pharmacodynamics and pharmacokinetics

When treating Proprotenom 100   modifying functional activity occurs S-100 protein Which carries information and conjugation metabolic processes in the brain. Furthermore, normal synthesis of neuronal membranes, modulation of synaptic plasticity of neurons. As a result, restored the function of brain structure, eliminating the formation of alcohol addiction , Hypothalamus and others. In patients suffering from alcohol dependence, normalized impact on positive reinforcement and emotional, leading to a decrease in the frequency of samostimulirovaniya   lateral hypothalamus.

Also decreases the activity of neurons in the hippocampus, reduced the number of circulating immune complexes in the peripheral blood, marked correlating decrease in consumption of ethanol. Admission Proprotena 100 enhances inhibitory effects of GABA in the central nervous system, restores the neurotransmitter balance and conditioned reflex function . At the same time it increases the stability of the brain to toxic effects and hypoxia .


Thus, treatment according to the drug helps alleviate psychiatric disorders, such as:   anxiety, mental stress, insomnia, irritability, anxiety, mood decline, a strong attraction to alcohol . Also, therapy can reduce or eliminate somatovegetativnye disorders Exhibited: weakness, sweating, headache, tremor, palpitations, digestive disorders . This drug is actively used to reduce or eliminate symptoms alcohol "hangover" syndrome .

And noted anti-alcohol effect of the drug that reduces the craving for alcohol and reduce the likelihood of relapse.

Indications for use of the drug

The main indication for the use Proprotena-100 is a monotherapy alcohol withdrawal syndrome mild to moderate severity.

Contraindications

Do not take this medicine if:

  • lactation, pregnancy ;
  • High individual sensitivity   the components of the drug.

Cautions

As is known, the composition of the preparation includes lactose, so it is not indicated in patients with congenital galactosemia and lactase deficiency, glucose malabsorption syndrome.

Side effects

Admission Proprotena 100 can cause a rare and brief cases accommodation disturbances   - Split in the eyes lasting about 5 to 10 minutes.

Do not rule out the development of the individual reactions of hypersensitivity to the drug.

Proproten 100: instructions for use (method and dosage)

This medicine is for oral administration, apart from the food. The drug is prescribed in tablets for one thing, and a drop of 10 drops to one-time appointment. This pill is recommended to keep the mouth until they are completely dissolved.

To remove   hangover   the drug must be taken every 30 minutes. installed in a single dosage.

Patients taking drops Proproten-100, instructions to the drug recommends that upon the occurrence of sleep, resume the reception immediately after waking up. If you check the weighting of alcohol withdrawal symptoms, it is necessary to supplement the treatment with other drugs that are commonly used in detoxification.

In carrying out the prevention of relapses, it is assumed the reception of a single drug dosage form according to any 1-2 doses a day for 2-3 months. Random alcohol requires additional reception double dose 2 times a day.

Overdose

In clinical practice, cases of overdose were observed. However, taking the drug can cause dyspeptic disorders , Intolerance to substances included in its composition.

Cooperation

Simultaneous reception Proprotena 100   with other drugs, generally does not cause symptoms of intolerance.

Nevertheless, the joint reception of various preparations can weaken or strengthen each other's actions. This may cause not receive the expected effect or bring to an overdose and even poisoning.

Terms of sale

The drug is available without prescription.

Storage conditions

The drug should be stored in a dry place inaccessible to children. At temperatures below 25 ° C.

Shelf life

3 years.

Analogs

Match code ATC 4th level:
  •  Proproten 100
 Lidevin
  •  Proproten 100
 Esperal
  •  Proproten 100
 Metadoksil

The main analogue of the drug on the active substance is Tenoten.

Alcohol and Proproten 100

The drug reduces the effect of alcohol and hangover. When the drug is used to eliminate the craving for alcohol, then from the use of any alcohol-containing drugs should be avoided.

Reviews Proproten 100

It should be noted that the drug is rarely discussed in the network. At the same time feedback on Proproten 100 are diverse. Particularly noteworthy published findings, when each form of the drug used to treat different patients. In this way, reviews of drops   Proproten 100 show that this formulation has a faster action. But reviews of tablets It contains information about virtually the same efficiency as that of the droplets.

If we look at the results in detail, approximately 50% of patients report improved health, 40% noticed a small positive effect of 6% for subjects treated Proprotenom 100 proved futile.

According to experts, to reduce the craving for alcohol is of great importance sincere desire of patients to get rid of this draft. As for the drug, then many people have noted a positive effect, but often require additional reinforcement therapy.

Price Proproten 100, where to buy

In Russian pharmacies price drops Proproten 100 varies within 190-250 rubles.

Price Proproten 100 tablets is 100-270 rubles, depending on the number of tablets.

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