Description overdue on 04/14/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Atarax (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Synonyms
• Babies
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The drug Atarax is a part of hydroxyzine hydrochloride   (active ingredient), and microcrystalline cellulose . lactose monohydrate, magnesium stearate . colloidal silicon dioxide . macrogol . titanium dioxide . hydroxypropyl .

Product form

Available in the form of tablets of elongated shape with a white envelope. They have
dividing the risk of cross on both sides. Tablets 25 mg packaged in blisters of 25 pcs., Sold in cardboard packs.

Pharmacological action

The main active ingredient of the drug Atarax - Hydroxyzine dihydrochloride   It is derived diphenylmethane . The drug is not a central nervous system depressant, but it can have a depressing effect on the activity of certain areas of the subcortical region.

Atarax has on the body antihistamine bronchodilatory and influence. If you take it in a therapeutic dose on acid-forming and secretory function of the influence occurs.

Effective influence in the course of therapy pruritus . allergic dermatitis . eczema . hives . If the patient is disturbed liver function, duration antihistaminic effect increases to 96 hours.

There simpatoliticheskoe, antispasmodic, mild analgesic influence. After taking the drug, patients reported an increase in the total duration of the sleep period, a decrease of awakenings during the night and the period, a decrease in muscle tone. Thus there is no memory impairment.

Pharmacodynamics and pharmacokinetics

Atarax drug absorbed in the intestine and rapidly enters the blood. Maximum plasma concentration observed in 2 hours after ingestion of tablets. Perooralnom reception bioavailability is 80%. Active substance hydroxyzine   It distributed throughout the body and mainly accumulates in the tissues.

Hydroxyzine can pass through the placenta and the blood-brain barrier. As a consequence, it is accumulated in fetal tissues in high concentration. Also metabolites pass into breast milk.

In the process of metabolism produced mainly hydroxyzine tsetarizin Which possesses histamine receptor antagonist properties.

Metabolites of the drug from the body is excreted unchanged in the urine.

Keep in mind that the elderly and those who suffer from impaired liver and kidney function during treatment with marked increased concentration of metabolites in the blood. So that did not show side effects, it is necessary to reduce the dose. What can take the tablets should in this case determined by the attending physician.

Indications

Tablets Atarax is indicated for the treatment of adult patients in the following cases:

• In order to eliminate manifestations of anxiety, inner tension, agitation, irritability, high in the treatment of patients with neurological, somatic, mental illness.
• In chronic alcoholism, as well as to eliminate the abstinence syndrome, which is accompanied by agitated.
• As a means of somatic during sedation.
• As a symptomatic treatment for elimination pruritus .

Indications Ataraxum determined by a physician. As a rule, the indications for use of the drug are available in a variety of skin diseases which are accompanied by severe pruritus.

Contraindications

Do not take Atarax if a person are the following diseases or conditions:

• pregnancy ;
• labors;
• breast feeding ;
• porphyria;
• high sensitivity to the components of the drug;
• High sensitivity cetirizine Derived piperazine As well as ethylenediamine   or Aminophylline .

Given that a part of funds have lactose should not take Atarax those who celebrated hereditary galactose intolerance, malabsorption of glucose and galactose.

Side effects

Atarax may provoke the manifestation of side effects due to the impact of the drug on the central nervous system. In particular, sometimes it causes inhibition of the function, the paradoxical stimulation has antihodinegichesky effect.

• Functions of the cardiovascular system : Rarely drops arterial pressure Increased heartbeat.
• Functions of : Reduction of visual acuity, disturbance of accommodation.
• Functions of the digestive tract : Feeling of dryness in the mouth, rarely - vomiting, nausea, bowel peristalsis problems and, as a consequence, constipation .
• The functions of the immune system : Hypersensitivity, may rarely develop anaphylaxis.
• The functions of the urinary system Rarely may be a delay of urine.
• Respiratory Function : Rarely - bronchospasm and dyspnea.
• Neurological disorders : Drowsiness, headache, insomnia, dizziness Rarely - seizures.
• Mental disorders   are rare: be excited, disorientation , Hallucinations.
• Skin : Itching, rash, rarely - swelling.
• General disorders Weakness, fever, fatigue.

Instructions for use Atarax (method and dosage)

Instructions on Atarax should be clearly demonstrated in the treatment of drug. The drug is taken by mouth. In the treatment of anxiety it is recommended to use 0, 05 pills daily. If the patient has severe degree of anxiety, a day can be taken 0, 3 grams of the drug.

Before surgery is recommended to take 0, 05-0, 2, the drug is given to patients one hour before surgery. Additionally you can take 0, 05 g of the night prior to anesthesia.

If we treat the itching, the patient was initially recommended to use 0, 025 g of the drug. If necessary, this dose may be administered Ataraxum 3-4 times per day. The largest dose, taken simultaneously, must not exceed 0, 2 g, and the dose per day should not exceed 0, 3 g

In the treatment of pruritus in children of preschool age (3 years) used a daily dose of 0, 001-0, 0025 g / kg body weight of the child.

Wikipedia shows that the dose is most often picked individually. It depends primarily on how the body responds to the treatment.

Overdose

With an overdose of the drug can be observed such phenomena:

• strengthening of anticholinergic effects;
• paradoxical stimulation or depression of the central nervous system;
• manifestations of spontaneous motor activity;
• nausea, vomiting;
• impairment of consciousness and hallucinations;
• hypotension, arrhythmia ;
• In rare cases, severe overdose - convulsions . tremor . disorientation .

When you receive too much of the drug is important to induce vomiting, gastric lavage. Practice measures that are aimed at supporting vital functions. The patient is monitored until until disappear all the symptoms of intoxication.

Cooperation

The impact of the drug on the body is enhanced if taken in conjunction with drugs that suppress the central nervous system function. If you need to take the drugs at the same time, the selection of doses doctor spends individually.

It should not simultaneously receive Atarax and preparations which belong to the group MAO inhibitors   and holinoblokatoram .

If at the same time taking Cimetidine   and Atarax, hydroxyzine enhanced concentration in plasma concentration of metabolites decreases.

Atarax violates the metabolism of substrates for preparatov- uridine diphosphate   and glyukuroniltransferazy .

When receiving Ataraxum potentiated the effect of drugs that inhibit the central nervous system: barbiturates . Opioid analgesics . tranquilizers , Hypnotics, ethanol.

Atarax suspend the pressor effect epinephrine   ( adrenaline ) And the anticonvulsant effect phenytoin It prevents exposure betagistina   and cholinesterase blockers .

Terms of sale

Pharmacies can be purchased by prescription.

Storage conditions

Keep Atarax must be in a dark, dry place where the temperature is not more than 25 degrees Celsius.

Shelf life

Store the drug can be 5 years.

Cautions

If the patient needs to spend allergological tests, drug treatment is stopped for five days prior to the survey.

Patients who are driving should take into account that the drug may have a note on the reaction rate and concentration.

If the patient has a history of convulsions appear, the drug treatment should be conducted very carefully.

Given the fact that Atarax has anticholinergic effects, be careful to use it for the treatment of patients with glaucoma . constipation . myasthenia . dementia . It should refrain from taking sedatives in the treatment of this drug.

Carefully prescribed the drug to patients with cardiac arrhythmia Those who applies antiarrhythmics. In the treatment of older people initially appointed half the dose.

Analogs

The network of pharmacies can buy analogues of this drug. One of the analogs of the drug is Hydroxyzine . The price of this product is lower (about 260 rubles per pack of 25 tablets). Other analogues of the drug are not completely the same composition.

Which is better: Phenibut or Atarax?

Phenibut   - Is a drug providing antihypoxia and nootropic effects. This drug effectively relieves anxiety, tension, normalizes sleep. The cost of the package Phenibut (20 pcs.) Is about 160 rubles. However, this drug is not a complete analog as the active ingredient Phenibut - aminofenilmaslyanaya acid . So make a decision on the replacement of one drug by another doctor can only.

Synonyms

Hydroxyzine.

Babies

The medicine is used to treat children from the age of one year, but you must strictly adhere to the specified dosage and Atarax used only after a doctor's prescription.

With alcohol

Alcohol and combining Atarax is impossible, as the use of alcohol increases the impact of the drug. Application Ataraxum alcohol causes significant inhibition of the central nervous system. Such a combination may enhance the state of intoxication, reduce blood pressure, cause allergic reactions.

During pregnancy and lactation

Atarax should not be used to treat pregnant women or during labor. The drug crosses the placenta and enters directly into the body of the fetus. During delivery   the drug can disrupt labor, as it relaxes the smooth muscles of the uterus and prevents its reduction. Breastfeeding Atarax enters the mother's milk, and the child under one year treatment with this agent is not carried out.

Reviews for Atarax

Reviews physicians about Atarax and feedback on the forum who have practiced this means of treatment is usually positive. Patients say that pills are effective in reducing the state anxiety, helps normalize sleep, relieve panic attacks. However, sometimes the medication causes constant sleepiness, lethargy, loss of ability to work. Reviews of reception children show that the correct dosage and admission under medical supervision tool helps eliminate the allergic reaction causing severe itching.

Price Atarax where to buy

Pharmacies price tablets in packs of 25 pieces on average from 310 to 330 rubles. 25 mg, 25 pcs. In Ukraine, you can buy the drug at a price of 50-60 USD. Buy in Moscow, and the drug can be at a lower price.