Description overdue on 08/19/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Tablets Host application instructions (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Synonyms
• Babies
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

Active substance - 15 mg doxylamine succinate.

Auxiliary ingredients:

• croscarmellose sodium a;
• lactose monohydrate;
• magnesium stearate;
• microcrystalline cellulose.

The film coating of tablets - opadry II White.

Product form

Film-coated tablets containing as active ingredient 15 mg doxylamine.

1 package can contain 10 or 30 tablets.

Pharmacological action

Sedatives, hypnotics, anti-allergic, antihistamine.

Pharmacodynamics and pharmacokinetics

Doxylamine refers to the group ethanolamines and has a blocking effect on H1-histamine receptors And pronounced M-anticholinergic and sedative effect.

Penetrating into the CNS has a soporific effect: making it easier to fall asleep, increasing the length and quality of sleep period, while not altering its physiological phase.

When taken orally, is well and rapidly absorbed in the digestive tract. It has a penetrating through g ematoentsefalichesky and the blood-placenta   barrier, excreted in mother's milk.

The processes of metabolism in the liver.

Doxylamine, unedited, as its metabolites derived mainly from urine and a small amount of feces.

Indications

The drug is used for treatment of Host insomnia   and conditions associated with sleep disorders.

Contraindications

• patient age of 15 years;
• Individual sensitivity to components of the drug substance;
• difficulty urinating (pathology of the prostate or urethra);
• angle-closure glaucoma;
• lactation.

Side effects

Often:

• morning drowsiness and impaired coordination of movements   (recommended dose reduction);
• ccomodation;
• dryness of the mouth;
• dizziness.

Rarely:

• urinary retention;
• constipation.

The side effects of doxylamine occur very rarely and are associated with it anticholinergic activity.

Tablets Host application instructions (method and dosage)

Instructions to determine the hosts of the drug as a remedy for oral (by mouth).

The initial dose for adult patients and patients in the age group 15 years after is 7, 5 mg - ½ tablet. The drug is recommended to take 15-30 minutes before anticipated bedtime.

Depending on the characteristics of each individual organism dose may be increased to 30 mg - 2 tablets Host. Instructions for use recommends this as the maximum dose.

Typically, an initial course of treatment is from 2 to 5 days. In case of failure of the treatment, with ongoing sleep problems, you should consult with your doctor to increase the dose or replace the drug. Maximum Sonmilom course of therapy may last for 2 months (not more).

Overdose

In overdose Sonmilom watched hypersomnia   in the daytime, anxiety, depression, tremors, incoordination, athetosis, facial flushing, mydriasis, hyperthermia.   In a few cases it was noted convulsions , and coma with cardiorespiratory collapse.

Recommends a symptomatic treatment, if necessary, the appointment of anticonvulsant drugs, mechanical ventilation (mechanical ventilation).

It should be noted that drinking large amounts of tablets Host, even in combination with alcohol, is not fatal, but it is definitely detrimental to the physical and psychological condition of the body.

Today the host of a lethal dose has not been established.

Cooperation

The inhibitory effect on the CNS ethanol, benzodiazepines, barbiturates, antipsychotics, opioids and clonidine When receiving Host may be more pronounced.

Sedation doxylamine substantially increase tranquilizers, anti-depressants   (with the exception of selective MAO inhibitors ), Cough medicines central action.

Combining the use of a Host antiparkinsonian agents holinoliticheskogo, atropine and atropine agents, antispasmodics, neuroleptics phenothiazine series, imipramine, disopyramide It increases the risk of manifestation of anticholinergic side effects ( constipation, urinary retention, dryness of the mouth ).

Terms of sale

The drug is released from a host of Russian pharmacies on presentation of a prescription.

In some countries, the drug enters the free market.

Storage conditions

Host drug store at a temperature not exceeding 25 ° C.

Shelf life

2 years.

Cautions

After taking the drug Host duration of sleep time should be less than 7 hours. Minimal during sleep can lead to morning drowsiness.

Advised to avoid sudden movements immediately after waking up, because of the possible slowing of the reaction.

It should refrain from drinking alcoholic beverages during treatment with Host.

Patients who suffer from impaired glucose uptake, lactose, galactose, be aware that the product contains lactose.

During treatment, you must take special care when driving a car or working with complex mechanisms.

Analogs

• Andante;
• Rohypnol;
• Brietal;
• Somnol;
• Imovan   etc.

Synonyms

• Sonniks ;
• Donormil;
• Sondoks.

Babies

Reliable information on the effects of doxylamine on patients aged less than 15 years, there is, therefore Host is contraindicated in this age group.

With alcohol

At the same time take the Host and alcohol is prohibited. Alcohol, even in small quantities, enhances the effects of the drug, which may lead to an overdose.

During pregnancy (and lactation)

Before using the Host, pregnant women need to undergo medical consultation, even though studies have not revealed doxylamine Phytogenic and teratogenicity   of the drug.

Doxylamine in a small amount detected in the mother's milk. Therefore, when receiving Host must give up breastfeeding or to find another drug.

Reviews Sonmile

Reviews Sonmile as a sleeping medicine, talk about the beginning of his soft steps, the practical absence of side effects and high efficiency even at a dose of ½ a tablet at a certain time interval.

Frequent use of the drug is likely to lead to an increase in the dose, and subsequently to low efficiency. Recall that the recommended course of treatment is 60 days Sonmilom.

Among the most commonly described side effects of the drug found - morning drowsiness,   passing an hour.

Price Host, where to buy

Price varies Host in Russia at the level of 110 rubles per 10 tablets and 250 rubles for 30 tablets.