Description overdue on 04/06/2014

  • Latin name: Mezapam
  • ATC code: N05BA03
  • Active substance: Medazepam (Medazepam)
  • Manufacturer: JSC "Organic" Novokuznetsk, Kemerovo region, Russia
Photos of the drug
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  • Description of the drug
  • Pharmacological action
  • Indications
  • Contraindications
  • Side effects
  • Overdose
  • Mode of application
  • Cautions
  • Cooperation
  • Analogs
  • Reviews
  • Price, where to buy

 Medazepam

Description of the drug

Tranquillizer . Active ingredient - medazepam . The drug has an antiepileptic, anxiolytic and muscle relaxant effects. The active ingredient belongs to the group of benzodiazepines. Instructions for use mezapama provides an indication of weakly expressed timolepticheskoe effects of medication.

Pharmacological action

Medazepam interact with benzodiazepine receptors activating the formation of the brain stem (the ascending portion) and limbic . The drug eliminates psychoneurotic tension , Anxiety, Rhinestone, increased restlessness, motor excitation.

The drug stabilizes the autonomic nervous system, restores emotional balance   and an adequate assessment of their own disease. Typical benzodiazepine tranquilizers have the most pronounced hypnotic, sedative and muscle relaxant action.

Indications

When irritability, agitation, nervousness, nervous tension appoint Medazepam. Instructions for use of medicines recommends withdrawal syndrome in patients suffering from alcoholism, climacteric syndrome and for prevention of migraines. Indications mezapama in pediatrics: irritability, mental lability , "School" neuroses.

Contraindications

Pregnancy, myasthenia gravis, intolerance medazepama, "Night" Apnea Pathology of the liver and kidneys, various forms of addiction (drugs, alcohol), breastfeeding.


When organic pathology of the nervous system, cerebellar ataxia, ocular hypertension, in spinal ataxia, respiratory failure, pregnancy Medazepam pills prescribed with caution.

Side effect

The digestive tract:   increased bilirubin, ALT, AST, dyspepsia, dry mouth.

Nervous system:   stupor, headache, paresis of accommodation , Dizziness, fatigue, ataxia, confusion, aggression, confusion, dysarthria, depression, ecmnesia , Disinhibition.

Cardiovascular system:   drop in blood pressure, heart palpitations.

Respiratory system:   COPD patients for the treatment of high doses recorded alveolar hypoventilation ; when brain damage and airway obstruction marked depression of the respiratory center.

Overdose

Improper dispensing medicament, namely medazepama taking high doses can lead to tachycardia , Ataxia, catalepsy, respiratory depression, hypotension, muscle tissue, fall in blood pressure. Required assignment enterosorbents Holding general measures aimed at stabilizing the state and restoration of the vital functions of the patient. Hemodialysis and forced diuresis considered ineffective.

Mode of application

Tablets Medazepam taken 2-3 times a day, starting with the lowest dose of 5 mg; amount of medicament is gradually adjusted to a value of 30 mg / day. In rare cases, it may be receiving 40 mg medazepama per day. In the context of outpatient treatment is recommended following scheme: 5 mg in the morning and 12:66, 10 mg - in the evening. In terms of hospital treatment, the maximum daily dose may be increased up to 60-70 mg. Duration of treatment - no more than 60days. After a month, you can hold a second course.

Cautions

Maybe impaired memory and attention , Reducing the learning during treatment. Invalid etanolsoderzhashih welcome drinks. Medazepam effect on driving vehicles. It is recommended that the phasing out of the drug in the treatment of withdrawal symptoms.

Long-term therapy may lead to the formation of medication depending on medozepama.

Drug Interactions

Strengthened interaction is observed in the treatment of antidepressants , Sleeping pills, barbiturates, central muscle relaxants , Drugs for general anesthesia, narcotic analgesics, when taking alcohol. The result of concurrent therapy beta-blockers, anticoagulants , Antihypertensives central effects are unpredictable.

Medazepam enhances the action phenytoin   (may slow   metabolic processes ), Reduces the effectiveness of levodopa . Oral contraceptives slow metabolism   Mezapama, which may lead to an increase in the duration and effectiveness of the medicament. Cimetidine   Extend the term of the severity and enhances the pharmacological effect medazepama.

Analogs

Match code ATC 4th level:
  •  Medazepam
 Grandaxinum
  •  Medazepam
 Sibazon
  •  Medazepam
 Seduxen
  •  Medazepam
 Ì
  •  Medazepam
 Lorazepam

Analogs mezapama:   Rudotel, Nobritem. Substitute mezapama can only be recommended by the attending physician, is unacceptable independent receiving analog without the consent of a doctor.

Reviews of preparation

Reviews mezapama indicate a good tolerability of the medicament in compliance with doctor's instructions and dosing regimen. Community health forums talk about individual cases of drug dependence , Urinary retention, reduced potency, paradoxical reactions, chest pain, allergic reactions, dysmenorrhea .

Price, where to buy

Price Medazepam varies by region (on average - 150 rubles). Where to buy Medazepam in Moscow at any pharmacy network, presenting a doctor's prescription form.

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