Description overdue on 08/22/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Neuleptila
• Contraindications
• Side effects
• Drops Neuleptil, instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

Depending on the form of the chemical composition of the drug may vary. In a 100 ml. Neuleptila drops (4% oral solution) contains 4 grams periciazine (active drug), as well as excipients such as purified water (100 ml.), glycerol   ('15) ascorbic acid   (0, 8 g),   butter Obtained peppermint leaves (0, '04) saccharose   (25) and E150d   (caramel, 0, 2 g) tartaric acid   (1, 65) and 96% ethanol   (9, 74 g).

One capsule contains 10 mg Neuleptila.   periciazine As well as such as the auxiliary connections magnesium stearate   (3 mg.) And calcium hydrogenphosphate dihydrate   (137 mg.). As part of the capsule itself contains chemicals such as the gelatin and titanium dioxide .

Product form

As a rule, placed a carton bottle made of dark glass solution with a fluorescent yellow-brown color with a minty odor, a nominal volume of 30 or 125 ml., Intended for oral administration. For ease of use of the drug preparation is equipped with a special syringe dosing.

№4 hard gelatin capsules, containing the active compound is acting as a yellow powder without smell filled into blisters of 10 pieces and placed in a cardboard box.

Pharmacological action

The drug has   sedative, antipsychotic, sedative, antispasmodic And, moreover, antiemetic pharmacological effects on the human body.

Pharmacodynamics and pharmacokinetics

Because the drug belongs to a group neuroleptics Which, in turn, are piperidine phenothiazine derivatives , Neuleptil blocks serotonergic, adrenergic and dopaminergic D2 receptors , and m-cholinergic receptors . The drug is no incentive component has on the body   antipsychotic And furthermore, sedative, antiemetic, parasympatholytics, adrenolytic and hypothermic effect .

Medicine potentiates the activity of non-narcotic , and narcotic analgesics and hypnotics . In addition, a drug exerting on the body sedation,   It reduces the level of aggressiveness and excitability and also acts as a sleeping pills. Since Neuleptil characterized selective normalizing effect , This drug belongs to correction means the behavior of children.

Indications Neuleptila

Indications for use Neuleptila considered mental disorders , including psychopathy, psychopathic disorders and paranoid state , eg, schizophrenia , and epilepsy . violent behavior . senile and presenile diseases .

Contraindications

This drug is not recommended for use under the following conditions:

• closure glaucoma ;
• Parkinson's disease ;
• porphyria   and   agranulocytosis , Including a history;
• disease prostate .

Everything else should not be taken together with Neuleptil Levodopa   in therapy Parkinson And in case of hypersensitivity to the active actions of the United periciazine   and other ingredients. With extreme caution drug should be used in elderly patients and those suffering from hepatic or renal failure   and from diseases of the cardiovascular system .

Side effects

When receiving Neuleptila can appear side effects of the drug such as:

• dyskinesia   ( oculomotor crisis . lockjaw . spasmodic torticollis );
• anticholinergic effects ;
• depression and mood swings ;
• extrapyramidal disorders ;
• dry mouth ;
• hypotension ;
• constipation ;
• urinary retention ;
• paresis of accommodation ;
• impotence ;
• amenorrhea ;
• frigidity ;
• drowsiness ;
• galactorrhea ;
• hyperprolactinemia ;
• gipertemiya ;
• gynecomastia ;
• weight gain ;
• jaundice ;
• agranulocytosis ;
• photosensitization .

Drops Neuleptil, instructions for use (method and dosage)

First of all, it should be emphasized that the dosage of the drug, as well as a timetable for its use depends on the condition of the patient, severity of the disease, as well as doctor's appointments. In addition, not the least important release form of the drug.

In accordance with the instructions on Neuleptil drops taken orally:

• adult patients in a dosage of 30 to 100 mg. 2-3 times a day;
• children who have reached three years of age at a dose of 0, 1 to 0, 5 mg. per one kilogram of body weight.

Above certain dosages can be adjusted in the event of an acute medical need. However, the maximum daily dose of medication for adults should not exceed 200 mg. The medicament capsules used in the treatment of adult patients, and use a similar dose of 30 to 100 mg. per day.

Overdose

Failure to follow the recommendations for dosage of the drug can lead to serious consequences, which are often expressed as extrapyramidal disorders . In some cases of overdose, patients fall into Neuleptilom whom .

Cooperation

It is strictly forbidden to use this drug in conjunction with Levodopa As it established the presence of mutual antagonism between these two drugs. Efficiency Neuleptila greatly reduced by the use of alcohol, as well as the simultaneous reception Guanethidine, sultopride and other drugs belonging to the antihypertensives   and Influence ventricular fibrillation.

With great care should be taken to sharing and Neuleptila antihypertensives , Drugs affecting the nervous system, as well as antacids, anticholinergics , Including atropine .

Terms of sale

Prescription.

Storage conditions

Since Neuleptil included in List B the expiration date the drug should be stored at a temperature not exceeding 25 ° C, out of reach of children and solar light.

Shelf life

4 years.

Cautions

When such a side effect of the drug as a fever   It should immediately consult a doctor to conduct a study of blood and eliminate agranulocytosis . During treatment Neuleptilom not allowed to drink alcoholic beverages.

When using the drug in the treatment of patients with epilepsy   it is recommended to carry out constant elektroentsefalogichesky control . In addition, special attention should be paid to the treatment of periciazine following groups of patients:

• the elderly;
• people suffering from diseases of the cardiovascular system ;
• with people kidney , and   hepatic insufficiency .

Since taking the drug may occur drowsiness Especially the first time, patients should abandon any activity requiring special attention (driving or work with potentially dangerous machinery).

Analogs

Currently, the main structural analogue Neuleptila can be considered such preparation as Periciazine.

Babies

The drug is contraindicated in children under the age of 3 years.

With alcohol

During the reception Neuleptil drink alcoholic beverages is prohibited.

During pregnancy (and lactation)

Although the use of the drug during pregnancy   not prohibited in some cases, long-term therapeutic treatment of women arose Neuleptilom extrapyramidal and gastrointestinal disorders , eg, abdominal distention   and others. So first of all, it is advisable to find out whether the intended benefits of the drug greater than the potential harm.

In addition, it is recommended to reduce the duration of treatment drug during pregnancy . If medical necessity requires the use of the drug in the III trimester, it is recommended to watch for a while   nervous system   newborn.

Due to the lack of reliable data on the effect of the drug on breast milk Neuleptil not recommended during Lactation .

Reviews Neuleptile

Although an impressive list of side effects of the drug many consider a significant disadvantage, the majority of patients consider the drug effective. The drug is in compliance with all of the recommendations does not harm children, opinions about Neuleptile parents often leave positive.

Price Neuleptila where to buy

Price Neuleptila (4% solution with a syringe dosing) by an average of up to 1,300 rubles per vial nominal volume of 125 ml.