Description overdue on 30.07.2014
- Latin name: Stresam
- ATC code: N05BX
- Active substance: Etifoxine (Etifoxine)
- Manufacturer: BIOCODEX, France
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Strezama
- Contraindications
- Side effects
- Stresa instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Reviews
- Price, where to buy
Composition
The structure 1 includes a capsule 50 mg etifoxine hydrochloride .
Auxiliary substances include: lactose monohydrate , Talc, microcrystalline cellulose, colloidal silica, magnesium stearate.
The shell composition includes titanium dioxide (E 171), indigotine (E 132), gelatin.
Product form
50 ml white powder without additives of any foreign smell and color in gelatin, shiny, smooth, capsules. The capsules have a white body and a blue cap.
The capsules are placed in contour cell blisters. In each carton pack is a guide to the instructions for use of the drug.
Pharmacological action
Anxiolytic ( sedative ).
Pharmacodynamics and pharmacokinetics
The main active ingredient in sedation is Stresam etifoxine hydrochloride Which has anxiolytic impact . Due to the fact that etifoxine hydrochloride has no effect on psychomotor speed, it can be used as a day tranquilizer .
Absorption
Etifoxine hydrochloride is rapidly absorbed from the gastrointestinal tract (within 2-3 hours).
Allocation
Etifoxine hydrochloride freely crosses the placental barrier.
Metabolism
The process metabolism It occurs in the liver with the formation of metabolites (dietiletifoksin).
Withdrawal
T1 / 2 of the basic substance ( etifoxine hydrochloride ) Is 5 - 6 hours, and the T1 / 2 metabolite ( dietiletifoksina ) - About 20 hours. Withdrawal of the drug in the urine and bile in an unchanged form (a small amount) in the form of metabolites.
Indications Strezama
Sedatives used to eliminate symptoms such as:
- alarm ;
- fear ;
- apathy ;
- reduced activity ;
- internal stress ;
- increased irritability ;
- depressed mood against the background of systemic diseases.
Additional indications for use:
- anxiety and phobic disorders ;
- autonomic dysfunction .
Contraindications
Do not use this anxiolytic Stresam at:
- hypersensitivity to the components of the drug;
- shock ;
- myasthenia ;
- severe violations of liver or kidney function;
- Congenital galactosemia ;
- malabsorption syndrome glucose / galactose ;
- lactose deficiency;
- pregnancy or breast-feeding .
Also, the drug can not be used in treatment of children and adolescents up to 18 years.
Side effects
Early treatment may be slight dizziness Which disappear on their own after a few days of taking sedative drug.
Sometimes Stresam may cause allergic reactions ( hives . angiodermit ).
Stresa instructions for use (method and dosage)
The duration of the course of treatment and the dose anxiolytic individually determined by a physician, as it depends on the patient's condition.
Stresam take 1 capsule (50 mg etifoxine hydrochloride ) Three times a day, or 2 capsules (100 mg of etifoxine hydrochloride ), 2 times a day. The capsules should be taken before meals and drink small amounts of water. The course of treatment may vary from a few days to 3-6 weeks. Instructions for use Strezama indicates that the maximum duration of the course - 12 weeks.
Overdose
In overdose symptoms hypotension . To eliminate these symptoms should be done as soon as possible gastric lavage with plenty of water.
No specific antidote.
Cooperation
Stresam enhances the effect of oppressive central nervous system. Caution should be used with this medication opioid analgesics . barbiturates . sleeping pills . antihistaminics . neuroleptics .
The drug also potentiates the effects of ethanol .
Terms of sale
Stresam can be purchased at the pharmacy with a prescription.
Storage conditions
Store at a temperature not exceeding 25 ° C.
Shelf life
Stresam kept for 3 years when stored.
Analogs
Anvifen
Afobazol
Phenazepam
Phenibut
Noofen
Tenotome
The main counterparts are tablets of the drug Stresam Trankvilara (Trancvilar) and Oksilidina (Oxylidinum). The most popular anxiolytics They are also Meprobamate (Meprobamat), Temazepam (Temazepam) and Amizil (Amizylum).
Reviews Strezame
Average rating reviews Strezame forums is 4 on a 5-point scale. Ins product forum visitors find:
- a mild sedative effect;
- absence sleepiness ;
- rapid elimination of anxiety.
On the downside of the drug panellists include:
- Highest price Strezama.
After analyzing the responses of physicians Strezame, we can conclude that this drug should pay particular attention to people who have a strong sedatives cause drowsiness . This drug does not cause this side effect, but, nevertheless, doctors are advised to follow when driving during treatment with the utmost vigilance and control of complex mechanisms and did not refuse.
Also, doctors are advised to use this drug for the treatment of sedation anxiety and phobic disorders in children and adolescents who have not yet reached the age of 18 years.
Information about the preparation Stresam Wikipedia there.
Price Strezama where to buy
The average price of a sedative Stresam in Ukraine vary between 136 and 145 USD.
Buy Stresam in Moscow can be over 195 rubles. (24 pcs.) And 450 rubles. (60 pcs.)