Description overdue on 08/08/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use of sumatriptan (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

As part of a single tablet contains 140 mg of sumatriptan. actively acting drug compound sumatriptan succinate .

In addition to preparation contains adjuvants such as: mannitol, calcium hydrogen phosphate dihydrate, giproloza, magnesium stearate, microcrystalline cellulose , and croscarmellose sodium.

The structure of the shell consists of a tablet makrolog, selekout AQ-02003 , and titanium dioxide .

Product form

Sumatriptan is produced in the form of tablets, coated with a film coating. In one carton, usually a blister contains two tablets.

Pharmacological action

The drug belongs to serotonergic group drugs that have protivomigrenoznoe impact.

Pharmacodynamics and pharmacokinetics

Activity Action drug compound sumatriptan Contained in the chemical composition of the drug, it refers to the specific selective agonist of 5-HT1 serotonin receptors Concentrated mainly in cerebral vessels . The medicine affects certain subtypes serotonin receptors , eg, 5-HT 2-7   and thereby promotes vasoconstriction arterial bed , The expansion of which leads to swelling and causes migraine .

It should be noted that sumatriptan not exert any significant effect on blood flow in the brain   and thus suppresses excessive activity receptors of the trigeminal nerve Which leads to lower discharge sensory neuropeptides at . The drug is rapidly eliminating migraine symptoms begin nausea , and photophobia .

The drug can effectively suppress migraine attacks   already after a single application dose up to 100 mg. Sumatriptan takes effect after a maximum of half an hour after its ingestion.

Indications

The drug compound is recommended for use when migraine   for the relief of acute attacks of the disease and further stabilization.

Contraindications

Use of the drug compound is prohibited when:

• oftalmoplegicheskoy, hemiplegic,   and basilar migraine form ;
• hypersensitivity ;
• coronary heart disease ;
• hypertension;
• myocardial infarction;
• diseases peripheral arterial disease Wearing occlusive character;
• renal insufficiency;
• stroke;
• epilepsy;
• liver failure;
• pregnancy And between Lactation ;
• angina .

In addition, the drug is not recommended to use in the treatment of patients under 18 years of age or elderly people over 65 years.

Side effects

During use, drug side effects may be expressed:

• the sudden decline and then raising Blood Pressure ;
• in development tachycardia and bradycardia;
• at heart rhythm disorders ;
• in the event of   nausea ;
• increase in activity liver transaminases ;
• in development dysgraphia , and ischemic colitis ;
• at dizziness , and   sleepiness   and weakness ;
• at seizures ;
• at   diplopia   and   decreased visual acuity;
• in the event of   skin rash Accompanied by   itching or anaphylactic reactions .

In some cases, may trigger the development of sumatriptan Raynaud's syndrome And symptoms myalgia .

Instructions for use of sumatriptan (method and dosage)

In accordance with the instructions on sumatriptan, a drug taken orally immediately after the beginning of the attack migraine . If necessary, the relief of acute attacks of adult patients can take 50-100 mg. drug pills washed down with water.

Repeated attack migraine   It can be taken once the minimum recommended dose of sumatriptan (50 mg.) after at least 2 hours after the first use of the drug. It should be noted that the maximum permitted dose of medical drugs should not exceed 300 mg / day.

Overdose

With an overdose of the drug in patients having adverse reactions described above. In such cases, immediately should contact your doctor and stop using the medication.

Cooperation

To avoid development serotonin syndrome , Increasing bioavailability of moclobemide, additive risk of hyperstimulation And the development of side effects of Sumatriptan should not be used in conjunction with   lithium salts, moclobemide, rizatriptanom Hypericum .

Terms of sale

We need a doctor's prescription.

Storage conditions

Sumatriptan should be stored at a temperature no higher than 25 ° C in a place protected from light and the reach of children.

Shelf life

3 years.

Cautions

The drug is not designed to prevent attacks migraine . It is worth remembering that after taking sumatriptan may develop allergic reaction patients with   hypersensitivity   on sulfonamides.

As the use of the drug may have a negative impact on Cardiovascular system , The drug is not prescribed to patients of the so-called risk groups (factor for coronary heart disease, men over 40 and women postklimatichesky period ) Without prior examination.

Before prescribing the drug for the first time to exclude others neurological diseases   patients. Everything else, it should be remembered that patients with migraine   may develop stroke, which hurt blood circulation in the brain .

During use of the drug should be approached with extreme caution to the management of vehicles, as well as any other activities that require attention.

Analogs of sumatriptan

The main counterparts of sumatriptan include drugs such as:

• Amigrenin;
• Sumitran;
• Rapimed;
• Migrepam;
• Sumamigren;
• Sumatriptan Teva;
• Trimigren;
• Imigran;
• Sumarin.

Babies

Do not use the drug in the treatment of children under the age of 18.

During pregnancy (and lactation)

Sumatriptan is contraindicated for use during the period pregnancy . It is not recommended to continue   breast-feeding   24 hours after the use of the drug.

Reviews of sumatriptan

While some patients are satisfied with the drug and leave good reviews about sumatriptan, the other as a negative factor, note the presence of fairly impressive list of side effects. So many refuse effective in the fight against migraine   drug only to avoid the development of side ailments and diseases.

Price sumatriptan, where to buy

Sumatriptan Price depends primarily on the region and the nominal volume. However, the average cost of the drug (50 mg pack.) Does not exceed 140 rubles.

Buy Teva sumatriptan (50 mg.) May be at an average price in the 110-130 rubles.