Description overdue on 05/15/2014
- Latin name: Avamys
- ATC code: R01AD12
- Active substance: Fluticasone furoate (Fluticasone Furoate)
- Manufacturer: GlaxoSmithKline Trading (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Avamys (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One dose of the drug contains the active substance - micronized fluticasone furoate - 27 + 5 mcg adjuvants ( cellulose, polysorbate, edetate disodium, dextrose, water ).
Product form
Nasal drops Avamys produce a white suspension homogeneous. The slurry contained in vials dark orange glass, with a volume of 30, 60 or 120 doses.
Pharmacological action
Anti-inflammatory corticosteroid.
Pharmacodynamics and pharmacokinetics
Avamys (Avamys) hormonal drug or not?
The medicine contains fluorinated corticosteroid So it hormonal drug But local action.
Getting on the nasal mucosa, the drug absorbed But not completely. It is metabolized in the liver, however, when taken in small doses in the amount of blood plasma can not be measured.
More than 99% fluticasone It binds to proteins. In the body (liver) is not split up fluticasone .
The output of the active substance from an organism through alimentary canal with feces.
Patients with kidney and liver (minor), the drug does not have a destructive effect on the body.
Indications
Avamys nasal sprays are prescribed for allergic rhinitis In the complex therapy.
Contraindications
Nasal spray to use caution when:
- severe liver diseases and disorders of its functions;
- drug allergy on the components of the drug;
- Together with the admission ritonavir ;
- Children up to six years.
Side effects
- bleeding from the nose;
- anaphylaxis, urticaria, angioedema, rash, skin;
- headache ;
- very rarely observed in children growth retardation .
Instructions on Avamys (method and dosage)
Drops are used intranasally . The drug takes effect within eight hours after application, usually the desired effect is achieved in one or two days after the start of use of the spray.
According to the instructions for use Avamys:
- Adults appoint two-spray in each nostril once a day;
- children 2-11 years - one in each nostril-spraying one time per day.
Bottle with spray equipped with a protective cap on the spray gun, a special window in the torus is visible level of the drug. The bottle 120 dose level may initially be hidden and becomes visible packing after prolonged use.
Prior to starting the medication vial should be shaken well (10 seconds) and make six " idle "Injections in the air. Then, on inspiration, sending the spray to the external wall of the nasal passage and holding the bottle vertically, to produce the desired number of clicks on the button sprayer (can be two fingers). After use, exhale through the mouth with a damp cloth to wipe dispenser and close the lid.
Not recommended:
- Avoid getting moisture in the spray;
- attempt to clean the dispenser with a pin;
- leave the bottle open, to prevent it from clogging and accidentally pressed the button;
- spraying the medication in your eyes (by ingestion - Rinse with clean water).
If sprayer stopped working:
- may run out of medicine, check the level in a special window;
- check for obstruction tip (do not try to use a pin to clean it);
- possible drug body has been damaged or left without cover for a long time;
- re-make training bottle, both before the first use.
Overdose
During clinical studies, even when using 50 doses daily for 4 days, overdosing does not occur.
Cooperation
During studies were not observed.
Not recommended combination with ritonavir Avoid mutually reinforcing effects fluticasone .
Terms of sale
Prescription.
Storage conditions
In the reach of small children. At a temperature of 0 to 30 degrees. Do not freeze the medicine.
Shelf life
In the closed state - 3 years.
After the first use - 2 months.
Analogs Avamys
Tafen Nazal
Nasobek
Polydex with phenylephrine
Fliksonaze
Nasonex
Nazarel
Bekonaze
Bekonaze, nazofan, Tafel Nazal, Nasonex, Polydex with phenylephrine Fliksonaze, Nasonex sinus flutineks .
Price analogs may differ significantly from the original.
Which is better: Nasonex and Avamys in adenoids?
Nazoneks - also hormonal drug from allergic rhinitis, but its cost is slightly higher than the original. In analogue wider scope and to a lesser extent it is metabolized in the body. Both drugs are prescribed for allergies and adenoids .
During pregnancy and lactation
As a general rule, during pregnancy and while breastfeeding medication is not prescribed.
Reviews for Avamys
Reviews of spray Avamys good. On the forums say high efficacy, ease of use. Nose drops relieve swelling of the nasal mucosa and relieve discomfort. The only thing that confuses - this is a relatively high cost and the fact that the drug is a hormonal agent.
Reviews in the sinus: Although the disease is not a direct indication to the reception means, it is administered frequently. Nasal spray is well relieves congestion and swelling, allowing other agents to freely penetrate to the site of inflammation.
Reviews at the reception Children : Doctors often prescribe at Avamys adenoids in children leads to improvement. Rarely there are cases of nasal bleeding (usually after a very long reception) and ulceration of the mucosa.
Price Avamys where to buy
The average price of a spray Avamys - 520 rubles per 120 doses of the drug. Buy doses of 30 drops in Ukraine will cost - 57 UAH 60 doses - 95 UAH.