Description overdue on 19.05.2012

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 Theraflu
 Combined preparation of influenza and colds . As part of the drug contains pseudoephedrine, paracetamol and chlorphenamine. Theraflu has analgesic, antitussive, sedative, vasoconstrictor, antipyretic, bronchodilator, antihistamine effects, can reduce the symptoms of colds and acute respiratory disease . Under the influence of psevdoefrina reduced congestion of the mucous membranes of the nasopharynx, nasal cavity, paranasal sinuses, local exudative manifestations, reduces swelling, narrowing the lumen of blood vessels. Chlorphenamine has antihistamine antiserotoninovym, sedative, slightly anticholinergic effects, a blocker of H1-histamine receptors. Under the influence of chlorphenamine eliminates puffiness, redness of the mucous membranes , Narrows lumen of blood vessels, decreases the severity of of allergic reactions, is suppressed rhinorrhea, sneezing Itching of the nose and eyes. Paracetamol is a non-narcotic analgesics, anti-inflammatory (poorly defined), antipyretic, analgesic effects. Terflu takes effect within 20 minutes after administration of the solution, the duration of exposure to 4 and 5 hours. Theraflu is available in the form of a sachet.

Indications:

Theraflu prescribed for sinusitis, rhinorrhea, rhinitis, colds, flu, allergic rhinitis, nasopharyngitis, hay fever, vasomotor rhinitis , Rhinosinusopathy.


Contraindications:

Theraflu is not indicated during pregnancy, intolerance of paracetamol psevdoefrina, chlorphenamine, breastfeeding, children until 12 years. In diseases of the blood, the form-closure glaucoma, congenital hyperbilirubinemia , Prostatic hyperplasia, kidney failure and liver, with Gilbert's syndrome, deficiency of glucose-6-phosphate dehydrogenase, chronic bronchitis, diabetes , Thyroid disease, Emphysema , Hypertension, comorbidity cardiovascular system, Rotor syndrome Theraflu used with caution.

Side effect:

Vomiting, insomnia, dizziness, hypererethism Pain in the epigastric area, vomiting, nausea, dry mouth, itching . mydriasis , Paresis of accommodation, urinary retention, thrombocytopenia , Increased intraocular pressure, angioedema , Pancytopenia, anemia, nephrotoxicity, aplastic anemia, hepatotoxity , Bronchospasm, allergic.

Overdose:

Overdose symptoms chlorphenamine: convulsions, agitation, depressed mood, coma, dizziness, sleep disturbances. Therapy posindromnaya. Symptoms of paracetamol overdose: increased prothrombin time, vomiting, nausea, gepatonekroz , Pale skin, eating disorders, increased liver enzyme system. Therapy aims to gastric lavage, administration of methionine, donators of SH-groups of acetylcysteine. Gastric lavage is performed to prevent late hepatotoxic effects .

Mode of application:

Theraflu are inside. The interval between doses is four hours per day is allowed to take no more than four bags. Pre-powder packets dissolve in a glass of boiling water.

Special instructions:

Invalid receiving alcoholic beverages during treatment with Theraflu. It is necessary to monitor the condition of liver, blood. Theraflu affects the speed of reaction, the reaction slows down when driving. In combination with hepatotoxic medicines Terflu capable damaging parenchyma liver.

Drug Interactions:

Theraflu enhances the effects of ethanol, sedative medications and drugs, MAO inhibitors. Antiparkinsonian, antipsychotic, phenothiazine medications antidepressants   significantly increase the likelihood of side effects in the form of constipation , Delays of urination, dryness in the mouth. In appointing glucocorticosteroids   significantly increased risk of developing glaucoma. Furazolidone , MAO inhibitors in combination with chlorphenamine lead to hyperpyrexia, excitation, hypertensive crisis. Under the influence of of paracetamol is reduced the effectiveness of urikouricheskih funds. Reception of of halothane causes a Ventricular arrhythmias And tricyclic antidepressants increase the sympathomimetic effects Theraflu. Efficiency is reduced when receiving guanethidine medicament.