Description overdue on 07/16/2013

Combined preparation. Effectively used to treat influenza, "cold" and symptoms of SARS. The structure Antigrippin includes the following active ingredients: ascorbic acid, chlorphenamine paracetamol. Ascorbic acid has antioxidant effects Has a positive effect on the permeability of capillaries, effectively increases the overall resistance of the organism. Chlorphenamine is a histamine receptor blocker, has antiallergic effects , To reduce swelling of the mucous walls of the airways. Paracetamol has antipyretic, analgesic effects . The drug is available in powder form and in tablet dosage form. Antigrippin for children comes in the form of effervescent tablets. Antigrippin maximum, which is now manufactured under the trade name Anvi-Max, has antiviral, immunomodulatory activity. Antigrippin homeopathic manufactured under the trade name Agri (20 mg pellets in duplex package).

Indications:

Powder Antigrippin prescribed for acute respiratory viral infection, colds, flu. The medicament may be used for the symptomatic treatment of acute rhinitis. Antigrippin homeopathy can be used prophylactically during a flu epidemic.

Contraindications:

Instructions for use of the drug is not recommended for Antigrippin drugs in the form of closure glaucoma with severe liver disease or renal systems, intolerant active ingredients of the drug, with hypertrophy of the prostate. When thalassemia, hemochromatosis, kidney and liver, giperoksalaturii at sideroblastic anemia When benign hyperbilirubinemia at progressirubschih malignancies, with sickle-cell anemia, leukemia, alcoholism, viral hepatitis , Pregnancy, elderly, with alcohol-induced hepatic system Antigrippin administered with caution when evaluating the potential risks and consequences.

Side effect:

Endocrine system:   development hypoglycemia   (possible coma). Central nervous system:   sensation of weariness, migraine. Digestive system:   epigastric pain, nausea. Bodies of blood:   rarely recorded thrombocytopenia, hemolytic anemia . Perhaps the development of of anaphylactic shock, epidermal necrolysis   (toxic form), exudative erythema, pruritus, angioedema . Rarely recorded changes in metabolism, supervitaminosis .

Overdose:

Higher doses of chloramphenicol can cause convulsions , Sleep disorders, dizziness, depressed mood, agitation. Higher doses of paracetamol is accompanied by nausea, vomiting, sweating, abdominal pain, epigastric discomfort, appetite disorders. The clinical picture of an overdose of the main symptoms manifested after 6-14 hours after ingestion of high doses of the drug. Treatment should be timelier, symptomatic.

Mode of application:

Powder Antigrippin before use diluted in a glass of water. Antigrippin children administered 1-2 times a day 1 tablet. The maximum allowable amount of daily medication - 3 tablets. Antigrippin homeopathic take 5 granules (until resorption is recommended to keep in the mouth).

Special instructions:

Responses to the drug Antigrippin demonstrate high efficiency of medication in the treatment of influenza and SARS. Ascorbic acid and acetaminophen can cause distortions in the laboratory tests and studies (liver transaminases, bilirubin, uric acid, glucose, LDH). Patients with alcoholic hepatosis   the risk of drug-induced liver significantly increased against the background of treatment with maximum Antigrippin. In patients with metastatic and rapidly proliferating tumors drug may worsen the overall condition. Antigrippin recommended for children on reaching the age of five. When an excess of iron in the body Antigrippin application can only minimum dosages because of the negative effect of ascorbic acid on ion exchange. Antigrippin price varies depending on the region and network of pharmacies (on average 150-200 rubles).

Drug Interactions:

Antigrippin able to raise the level of antibiotics tetracycline and penicillin in the blood. The drug enhances and stimulates the absorption of iron supplementation (due to the transition to the divalent iron trehvaletnogo). Simultaneous treatment with deferoxamine may cause enhanced removal of iron from the body. The medicament reduces oral contraceptives , Increases the excretion of drugs that have an alkaline reaction (eg, alkaloids), slows down the process of removing acid renal system, increases the probability of formation of crystalluria in the treatment of short-acting sulfonamides and salicylates. Antigrippin able to increase the total clearance of ethanol. Simultaneous treatment reduces the severity of his isoprenaline chronotropic effect . The medicament is able to reduce therapeutic effect of neuroleptics, antipsychotics, tricyclic antidepressants , Phenothiazine derivatives. The drug interferes with the action of anticoagulants. Tricyclic antidepressants, phenylbutazone, rifampicin, ethanol, phenytoin, barbiturates and other inducers of microsomal oxidation in the liver tissue increases the production of active metabolites of paracetamol hydroxylated, which could have serious hepatotoxic effects even with small overdoses. The risk of hepatotoxicity of paracetamol significantly reduced while treating cimetidine   and other inhibitors of microsomal oxidation. Ethanol can cause acute pancreatitis, and also reduces the level of ascorbic acid. Antigrippin improves sleeping pills.