Description overdue on 08.09.2011

Non-narcotic analgesic and antispasmodic. Spazmalgon   in its composition comprises Metamizole .   (myotropic antispasmodic drug) and fenpiveriniya bromide   (m-holinoblokator). Metamizole has antipyretic, analgesic, anti-inflammatory effects. Pitofenone relaxes the smooth muscles of internal organs. Fenpiveriny further relaxes smooth muscles, providing m-anticholinergic effects. The three main components of the drug in combination Spazmalgon relax and relieve pain, reduce fever, relaxes smooth muscle.

Indications:

The pain syndrome mild to moderate severity in patients with renal, hepatic colic, algodismenoree . It can be used for the purpose of symptomatic short-term treatment neuralgia, joint pain, myalgia, sciatica. It is used as an auxiliary anesthetic after diagnostic and surgical procedures. When infectious and inflammatory and respiratory diseases effectively reduces high body temperature.

Contraindications:

Allergies to components of the drug, derivatives pyrazolone . angina , Inhibition of bone marrow hematopoiesis, chronic heart failure (Art. decompensation ), Serious violations in the work of the kidneys, liver, tachyarrhythmia, prostatic hyperplasia with urinary retention, angle-closure glaucoma, granulocytopenia, megacolon, pregnancy (first trimester, 6 weeks), lactation. The drug is contraindicated in children younger than 6 years. Spazmalgon prescribed with caution in diseases of the kidney, liver systems, low blood pressure (systolic index below 100 mm Hg. V.), The propensity to bronchospasm.

Mode of application:

Adults, children older than 15L: 1-2 tablets after meals 2-3 times a day. The maximum daily dose should not exceed 6 tablets. Reception period not more than 5 days. Spazmalgon children: 6-8 L - 1/2 tablets, 9-12 liters - for ¾ tablet, 13-15 liters - of 1t. 2-3r day.

Side effects:

Dry mouth, burning sensation in epigastric . Dizziness, headache, decreased sweating, difficulty urinating, paresis of accommodation. Cyanosis . tachycardia , Lowering blood pressure. , Violation of the kidneys, anuria , Interstitial nephritis, polyuria , The color of urine red. Agranulocytosis, leukopenia, thrombocytopenia - chronic administration. Allergic reactions: bronchospasm, urticaria, anaphylaxis, Stevens-Johnson syndrome, Lyell's syndrome, angioedema .

Overdose:

Symptoms: dry mouth, vomiting, disturbance of accommodation, decreased sweating, drop in blood pressure, confusion, drowsiness, seizures, abnormalities in the kidneys and liver. Treatment is aimed at gastric lavage, activated charcoal.

Connectivity:

Spazmalgon and narcotic analgesics   while receiving may increase the toxic effects of drugs. Allopurinol , Coca tricyclic antidepressants violate Metamizole metabolism in the liver, resulting in increased toxicity. Inductors of microsomal liver enzymes decrease the effectiveness of metamizol. Tranquilizers and sedatives increase the intensity of analgesia. Simultaneous administration of cyclosporine and spazmalgona reduces the concentration in the blood first. Spazmalgon enhances the effect of ethanol. Simultaneous treatment with phenothiazine derivatives raises the body temperature. Tiamazol cytostatics and increase the risk of leucopenia. The efficacy of H2-blockers increase gistamivyh receptors, Codeine, .

Special instructions:

While taking the drug for more than 7 days is necessary to monitor patterns of peripheral blood to assess the condition of the liver. In the presence of thrombocytopenia, agranulocytosis suspected, you must terminate the application spazmalgona. During treatment, it is forbidden to drink alcohol. Spazmalgon reduces the speed of mental and physical reactions.