Description overdue on 26.05.2012

Digestive, enzymatic drug. The main ingredient is pancreatin . Creon has amylolytic, proteolytic and lipolytic effects, the drug is able to compensate for the deficiency of enzymes necessary for normal operation pancreas.   The drug composition comprises pancreatic enzymes such as trypsin , Lipase, chymotrypsin, alpha-amylase. They normalize the digestive process, improves the functional state of the digestive tract, contribute to the breakdown of starch to sugars and dextrin, fats - into fatty acids and glycerol to, proteins - up of amino acids. Under the action of trypsin inhibits the secretion of pancreatic juice, is provided analgesic effect . The release of the pancreatic enzymes carried in the lumen of the small intestine (alkaline), the drug is protected from the damaging effects of gastric juice special coating. The highest enzymatic activity of the drug observed after 40 minutes after administration of the medicament. Creon produced in the form of tablets, dragees, capsules. Dosage: Creon 10 000 units, 25 000ED, 40 000 units.

Indications:

Creon is prescribed as replacement therapy in violation of the exocrine function   Pancreatic cancer: pancreatectomy, chronic form pancreatitis . dyspepsia , Bloating, flatulence, condition after irradiation, diarrhea infectious etiology, cystic fibrosis. The drug is prescribed for violation of assimilation of food intake, after the resection of the small intestine after gastrectomy,   with prolonged immobilization, with errors in diet (intake of low-quality food, irregular, infrequent meals, intake of a large amount of food, excessive consumption of fatty foods), the conduct of a sedentary lifestyle, the pathology of the masticatory function. Creon 10000 is assigned to the US and holding X-ray inspection   abdominal cavity. The drug is indicated for gastrocardiac syndrome   (Remhelda syndrome).

Contraindications:

Creon does not appoint an exacerbation of chronic pancreatitis, acute pancreatitis when intolerance and pancreatin.

Side effect:

Creon can trigger an allergic response, cause diarrhea or constipation, discomfort in the epigastric area. Prolonged therapy with high-dose leads to hyperuricosuria, and in patients with cystic fibrosis   the drug can lead to the formation of strictures in the ascending portion of the colon, the ileocecal region.

Overdose:

Contact with large doses may cause pancreatin hyperuricemia , Hyperuricosuria and young children are marked constipation . The therapy is based on the cancellation of an overdose of the drug Creon and posindromnom treatment.

Mode of application:

Creon 10 000 IU administered during or after a meal. The drug is washed down with plenty of water, swallow whole. Dosage of the drug is dependent on the degree of insufficiency of the pancreas and the age of the patient. The average dose for adults - 150 thousand. Units; full failure of the pancreas (exocrine insufficiency) appointed 400 thousand. units per day, which coincides with the daily requirement of an adult human lipase. The day is not more than 15-20 thousand units per 1 kg of body weight. The course of the drug Creon 10,000 units ranging from a few days (with errors in diet, digestive disorders) to several months if necessary continuous replacement therapy.

Special instructions:

When long-term therapy drug Creon necessarily appointment iron supplementation .

Drug Interactions:

Creon reduces the absorption of iron.