Description overdue on 10.05.2012

Antiulcer agents . The main component is rabeprazole . The active substance belongs to the group of proton pump inhibitors. Principle impacts medicament founded on blocking final stage of elaboration of hydrochloric acid in the stomach, on reducing of detention stimulirovannoj, basal secretion HCl, in independence from nature of the active stimulus. Geerdin easily penetrates parietal cells   gastric wall, highly lipophilic, increases the secretion and production of hydrogen, has cytoprotective exposure . After oral administration antisecretory effect is recorded in an hour. The drug has no effect on the respiratory, cardiovascular and central jealous system. Geerdin comes in tablet form in a special, enteric film.

Indications:

Geerdin prescribed for peptic ulcer   the digestive system, with stress ulcers in the stomach, Zollinger-Ellison syndrome, reflux esophagitis .

Contraindications:

Geerdin not apply in case of intolerance rabeprazole, pregnancy, breastfeeding. In the pathology of the renal system, the children used with caution.

Side effect:

Flatulence, disturbances stool, nausea, epigastric pain, increased liver enzymes, headache, pharyngitis , Leukopenia, thrombocytopenia, fatigue, rhinitis, dizziness, cramps in the calf muscles, fever, arthralgia, dry mouth, myalgia, flu syndrome, stomatitis, depression , Decreased appetite, increased sweating.

Mode of application:

Geerdin taken in the morning on 20 mg inwardly. Duration of anti-ulcer therapy is 4-6 weeks, with relyuks esophagitis drug taking 4-8 weeks. The tablets are not recommended crush, chew.

Special instructions:

Before and after care is required to conduct endoscopy to rule out cancer pathology. The drug does not affect the metabolism of carbohydrates, work Thyroid , Prolactin, estrogen, cortisol, Testosterone , Cholecystokinin, aldosterone, renin, glucagon, growth hormone, parathyroid hormone.

Medicine:

Geerdin reduces the rate of excretion of drugs whose metabolism is carried out by of microsomal oxidation   in the hepatic system. Geerdin reduces the concentration of digoxin and ketoconazole .