Description overdue on 09/29/2014

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Omez Insta (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The composition of the powder for suspension Insta omez   part of the active substance omeprazole And auxiliary ingredients xylitol, sodium bicarbonate, sucralose, sucrose, xanthan gum, mint flavoring.

Product form

Omez Insta made in the form of an off-white powder having a distinct odor of mint. Powder fit into sachets made of composite material. The cardboard box is embedded 5, 10, 20, 30 packages.

Pharmacological action

Omeprazole reduces the level of acid production in the body by blocking the final step of acid secretion. Under the influence of substances inhibited both basal and stimulated acid secretion irrespective of the factors which stimulate these processes. As a consequence, the symptoms Heartburn   after receiving means disappearing after 30 minutes.

Pharmacodynamics and pharmacokinetics

Inhibition of 50% of the maximum secretion of hydrochloric acid lasts for 24 hours.

If the patient is taking the drug one time per day, the night and day inhibited the secretion quickly and efficiently. The most pronounced effect was observed four days after the start of therapy, it disappears in about 3-4 days after completion of treatment.

Absorbed quickly, the highest concentration is observed after 30 minutes, bioavailability - about 30-40%. The half-life is equal to 0, 5-1 hours.

The substance is almost the end of metabolized in the liver. Because the body is derived through the kidneys (most about 80%) and in the bile.

Indications

Omez Insta prescribed to patients with such conditions and diseases :

• GERD (non-erosive and erosive forms);
• attacks Heartburn As well as other symptoms of GERD;
• NSAID-gastropathy;
• peptic ulcer   (used to prevent relapses);
• Helicobacter pylori eradication in people suffering from peptic ulcer disease (as part of combination therapy);
• hypersecretory conditions.

Contraindications

Do not take the remedy for these conditions and diseases :

• high sensitivity ;
• galactose malabsorption glucose;
• fructose intolerance;
• shortage in the body or sucrase isomaltase;
• pregnancy   and period breastfeeding ;
• children's age.

Do not use Omez Insta simultaneously with nelfinavir and atazanavir.

Carefully applied remedy for liver and kidney failure.

Side effects

Rarely when taking medication there are some   side effects :

• Thrombocytopenia, leukopenia, in very rare cases may develop agranulocytosis, pancytopenia.
• Constipation . diarrhea , stomach ache, flatulence , Vomiting, and in rare cases, may be a manifestation of dry mouth, stomatitis, rarely developing encephalopathy.
• Headache In rare cases - drowsiness . dizziness , Taste disturbance.
• Insomnia In rare cases - depression , Confusion, hallucinations .
• Vertigo, in rare cases - blurred vision.
• Myalgia, arthralgia, in rare cases - muscle weakness.
• Itching of the skin . dermatitis . hives In rare cases - photosensitivity, alopecia .
• Hyponatremia, in rare cases - hypomagnesemia.
• Perhaps the high sensitivity of the response.
• It might appear malaise, bronchospasm.

Instructions for use Omez Insta (method and dosage)

Instructions for use Omez Insta provides the drug in approximately 30 minutes before eating. The powder from the package need to pour into a bowl, add a little water (1-2 tablespoons) and mix to obtain a homogeneous suspension, and drink immediately after preparation. You can drink water.

To remove an attack of heartburn, it is enough to take one time of 20 mg of the drug.

Treatment of GERD (non-erosive form): daily, 20 mg, therapy - 4 weeks.

Treatment of GERD (erosive form): daily 2 x 20 mg therapy - 4-8 weeks.

In order to prevent aggravation of reflux esophagitis - a day to 20 mg, the duration of this treatment is set individually.

Peptic ulcer: a day to 20 mg treatment - 4-8 weeks.

Peptic ulcer disease (prevention), hypersecretory conditions: daily 20 mg taken in the morning, treatment - 4-8 weeks.

In the treatment of Zollinger-Ellison syndrome, dose selection is carried out individually, it is recommended to start the process of therapy with 60 mg per day. If assigned a higher dose of 80 mg, it must be divided into 2 times.

No need to adjust the dose for the elderly.

Overdose

In overdose Omez Insta may develop the following symptoms: confusion, dizziness, symptoms of sleepiness, headache, arrhythmia, impairment of consciousness, vomiting, dry mouth, blurred vision. In this case, stomach wash, take a tablet of activated charcoal, symptomatic treatment.

Cooperation

Because the treatment omeprazole   reduced gastric acidity, the absorption of other drugs may be reduced or increased.

In particular, while treatment decreases the absorption of itraconazole and ketoconazole.

Omez increases absorption of digoxin. When combined treatment of omeprazole 20 mg 1 time per day increases the bioavailability of digoxin, 10%.

In a joint reception omez and antiretroviral drugs (Nelfinavir, atazanavir) concentration in the blood decreases.

When combined omeprazole and saquinavir, concentration in the blood rises.

When concurrent therapy of omeprazole and phenytoin, warfarin, diazepam, cilostazol, other antagonists Vitamin K   metabolism of these drugs may be reduced.

In the treatment of both phenytoin and omeprazole is sometimes necessary to reduce the dose of phenytoin. It should monitor the level of phenytoin in plasma.

In treating both omeprazole and Tacrolimus Tacrolimus concentration in serum increases.

The combined treatment with clarithromycin, voriconazole and omeprazole may lead to increased concentration of omeprazole in blood.

In the treatment of both omeprazole and rifampin, and St. John's wort preparations concentration of omeprazole in the blood decreases.

Terms of sale

Omez Insta can be purchased by prescription.

Storage conditions

Protect the medicine from moisture and light, stored at a temperature not exceeding 25 degrees.

Shelf life

Shelf life funds - 2 years.

Cautions

Before starting treatment, should be excluded malignant gastrointestinal diseases, as in therapy may mask the symptoms of such diseases.

Can take the medicine together with food.

In the treatment of the drug may develop drowsiness and dizziness, so be careful to drive vehicles and to carry out other activities that require attention.

Analogs

Analogs Omez Insta - a drug with the same active ingredient: Gastrozol . Vero Omeprazole . Zerotsid . Demeprazol . Omeprazole . Omezol . Omekaps   and etc.

Babies

Children's age is a contraindication to receiving Omez Inst.

During pregnancy and lactation

Not appointed pregnant As well as women during Lactation .

Reviews

In a review of Omez Insta celebrated its effectiveness under constant attacks of heartburn during exacerbation ulcers . gastritis . There is also the convenience of using the drug, its quick action, the almost complete absence of adverse events.

Price Omez Insta where to buy

The price of the drug package (5 pcs.) On the average is 70-80 rubles.